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Sleep-disordered breathing

Part of Sleep Disorders, Intrinsic

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for sleep-disordered breathing

37 trials tracked for sleep-disordered breathing: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 11 citations.

37Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 1 Phase 2 5 Other / NA 31
  1. Phase 4 Sleep and Breathing in the General Population - Chemical Stimuli Completed · 11 cited
  2. Phase 2 Role of Mirtazapine in Ameliorating Sleep Disordered Breathing Completed
  3. Phase 2 To Characterize the Performance of the Nasal Dilator Strip in Lowering Nasal Resistance During Sleep, Promoting Nasal Route Breathing and Reducing the Signs and Symptoms of Sleep Disordered Breathing in a Group of Chronic Nocturnal Nasal Congestion Sufferers Who Report Trouble With Their Sleep. Completed
  4. Phase 2 Chronic Evaluation of Respicardia Therapy Completed
  5. Phase 2 A Pilot Study of the Effects on Sleep Disordered Breathing (SDB) When Using the Drug Liraglutide for 4 Weeks Completed
  6. Phase 2 Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI Completed
Show 31 more trials
  1. N/A A Multi-Center Study to Assess the Performance of Saturation Patterns. Completed
  2. N/A Belun Ring Platform With an Improved Algorithm for OSA Assessment Completed
  3. N/A Peak(R) vs. Electrocautery in Children Undergoing Tonsillectomy With Adenoidectomy Completed
  4. N/A Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome Completed
  5. N/A CPAP vs ASV for Insomnia Completed
  6. N/A Treatment of Predominant Central Sleep Apnoea by Adaptive Servo Ventilation in Patients With Heart Failure Completed
  7. N/A Sleep Disordered Breathing, Obesity and Pregnancy Study (SOAP) Completed
  8. N/A Oxygen Monitoring of Patients After Surgery on the Hospital General Care Floor Completed
  9. N/A Comparison of 2 Different Hook-up Protocols to Perform Home-based Polysomnography Completed
  10. N/A ApneaLink Air Home Sleep Testing (HST) Device Validation Study Completed
  11. N/A Determination of the Predictors of Nocturnal Desaturation in Postpartum Women Completed
  12. N/A Respicardia, Inc. Pivotal Trial of the remedē System Completed
  13. N/A Sleep-Disordered Breathing and PAP in Perinatal Depression Completed
  14. N/A Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy Completed
  15. N/A Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders Completed
  16. N/A Pediatric Adenotonsillectomy Trial for Snoring Completed
  17. N/A Adenotonsillectomy for Obstructive Sleep-Disordered Breathing in Childhood:The Chania Community Oximetry-Based Study Completed
  18. N/A Evaluation of a "Fast Track" Respiratory Therapy Clinic for Patients With Suspected Severe Sleep-Disordered Breathing Completed
  19. N/A Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea Completed
  20. N/A Impact of Exenatide on Sleep in Type 2 Diabetes Completed
  21. N/A Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism Completed
  22. N/A Effect of Treatment of Sleep Apnea in Patients With Paroxysmal Atrial Fibrillation Completed
  23. N/A Alice PDx User/Validation Extended Trial Completed
  24. N/A Heart Function in Patients Assessed for Sleep Apnoea Completed
  25. N/A Evaluation of Software Enhancements to the Respironics BiPAP Auto Servo Ventilation (AutoSV) Device Completed
  26. N/A Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm Completed
  27. N/A Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention Completed
  28. N/A User Preference/Validation Evaluation of the New Philips Respironics Positive Airway Pressure Application Completed
  29. N/A Treatment of Sleep-disordered Breathing in Patients With SCI Completed
  30. N/A Apnea Hypopnea Index Severity Versus Head Position During Sleep Completed
  31. N/A Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease Completed

Showing the 37 most-cited and recently-updated of 37 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Sleep Disorders, Intrinsic

Related studies from across the Sleep Disorders, Intrinsic family.

DaVinci Single-Port transoral robotic surgery is feasible across multiple indications including oncology and sleep apnea
Oncology Meta-analysis
DaVinci Single-Port transoral robotic surgery is feasible across multiple indications including oncology and sleep apnea Single-Port Robot Shows Promise for Sleep Apnea Surgery
This systematic review and meta-analysis of 479 patients evaluates the feasibility of DaVinci Single-Port (SP) transoral robotic surgery (TO…
A new analysis finds single-port robotic surgery for sleep apnea is feasible, with short operating times and low blood loss.
Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
Nutrition & Obesity Medicine Meta-analysis
Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults Pre-existing health conditions may slightly reduce weight loss after surgery
A meta-analysis of twenty-three studies reveals that mental illness, diabetes, and sleep apnea are associated with slightly lower weight los…
Adults with mental illness or diabetes before surgery saw slightly less weight loss. Other conditions like high blood pressure did not affec…
1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds
Pulmonology & Critical Care Meta-analysis
1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds 1 in 7 COPD patients decline or stop breathing therapy
This systematic review and meta-analysis of patients with COPD newly prescribed long-term noninvasive positive airway pressure (PAP) therapy…
A new analysis finds 14% of COPD patients decline or stop long-term breathing therapy, often within six weeks.
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
Rheumatology Sys. Review
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia Non-invasive ventilation may help patients with Madelung's disease and respiratory failure
This case series describes non-invasive ventilation using a total face mask in two patients with Madelung's disease who experienced acute re…
A small case series suggests non-invasive ventilation can manage acute respiratory failure in patients with Madelung's disease, though more …
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
Cardiology Meta-analysis
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients Renal denervation may help resistant hypertension patients with heart issues
This systematic review and meta-analysis evaluated renal denervation in patients with resistant hypertension. The pooled analysis included 8…
A meta-analysis suggests renal denervation improves heart and sleep markers in patients with resistant hypertension, though larger trials ar…
Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients
ENT (Otolaryngology) Meta-analysis
Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients Radiation for head and neck cancer may raise sleep apnea risk
This scoping review with exploratory meta-analysis of 13 studies found no significant association between radiotherapy or chemotherapy and i…
A review of 13 studies suggests a possible link between radiation for head and neck cancer and mild sleep apnea, but the evidence is too wea…
Non-surgical weight loss reduces AHI by 11.10 in adults with obstructive sleep apnoea
Primary Care & Family Medicine Meta-analysis
Non-surgical weight loss reduces AHI by 11.10 in adults with obstructive sleep apnoea Non-surgical weight loss lowers sleep apnea severity and blood pressure in adults
This systematic review and meta-analysis evaluated non-surgical weight loss interventions in adults with obstructive sleep apnoea. The poole…
Non-surgical weight loss significantly reduced sleep apnea severity and blood pressure in adults, though long-term results remain uncertain.
MAD shows modest BP benefit over CPAP in OSA patients
Neurology Meta-analysis
MAD shows modest BP benefit over CPAP in OSA patients Mandibular advancement devices lower blood pressure better than CPAP for some patients
A meta-analysis found mandibular advancement devices slightly outperform CPAP for lowering daytime blood pressure in obstructive sleep apnea…
For patients with obstructive sleep apnea, a new analysis shows mandibular advancement devices reduced daytime blood pressure more than CPAP…
Delayed arousal timing links to higher mortality in sleep apnea patients
Pulmonology & Critical Care Meta-analysis
Delayed arousal timing links to higher mortality in sleep apnea patients Timing of breathing pauses predicts death risk in obstructive sleep apnea
A meta-analysis found that each one-second delay in post-apnea arousal peak time was associated with increased all-cause and cardiovascular …
New analysis shows how late a breathing pause wakes you up predicts higher death risk for men with obstructive sleep apnea.
Meta-analysis links moderate-to-severe obstructive sleep apnea to higher metabolic syndrome risk in patients
ENT (Otolaryngology) Meta-analysis
Meta-analysis links moderate-to-severe obstructive sleep apnea to higher metabolic syndrome risk in patients Patients with worse sleep apnea face higher risks for diabetes and high blood pressure compared to those with milder cases
This meta-analysis evaluated the association between obstructive sleep apnea syndrome (OSAS) severity and metabolic syndrome risk. The poole…
A large review of over ten thousand patients shows that worse sleep apnea greatly increases the chance of getting metabolic syndrome, high b…
Meta-analysis finds obstructive sleep apnea associated with sarcopenia in adults
ENT (Otolaryngology) Meta-analysis
Meta-analysis finds obstructive sleep apnea associated with sarcopenia in adults Sleep apnea linked to higher muscle loss risk in many adult groups studied
This meta-analysis of 13,331 participants found a significant association between obstructive sleep apnea syndrome and sarcopenia. The assoc…
A large review of 13,331 adults found that sleep apnea is connected to losing muscle mass. The link is especially strong in older people and…
Systematic review and meta-analysis shows Twin-Block appliance reduces AHI in pediatric obstructive sleep apnea
Pediatrics Meta-analysis
Systematic review and meta-analysis shows Twin-Block appliance reduces AHI in pediatric obstructive sleep apnea New analysis shows Twin-Block appliance helps children with sleep breathing problems reduce bad sleep scores significantly
This systematic review and meta-analysis evaluated the Twin-Block appliance for pediatric obstructive sleep apnea. Data from 259 patients ac…
A review of eight studies found that a special mouth appliance called Twin-Block helps children with sleep apnea. It lowers breathing stoppa…

Questions about sleep-disordered breathing

Do children with sleep-disordered breathing benefit from turbinate ablation?

Adding turbinate ablation to adenotonsillectomy does not provide extra benefit for children with sleep-disordered breathing compared to adenotonsillectomy alone.

Full answer →
Can machine learning detect sleep-disordered breathing events as well as experts?

Machine learning models can detect sleep-disordered breathing events with accuracy comparable to expert human scorers, though performance varies slightly depending on the specific task.

Full answer →