Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
Traditional Chinese medicine metabolites protect brain cells from damage
This review examines the utility of Traditional Chinese medicine (TCM) metabolites for neurological conditions including Alzheimer's disease…
A review shows Traditional Chinese medicine metabolites protect brain cells through anti-inflammatory and anti-oxidative stress actions, off…
Systematic review of neural progenitor cell transplantation for spinal cord injury
New review shows stem cell treatments for spinal cord injury are still in early testing stages
This systematic review synthesized evidence from 19 clinical trials on neural progenitor cell transplantation for spinal cord injury. The au…
A review of nineteen trials from ten countries found that stem cells might help spinal cord injury patients recover movement. However, no tr…
Systematic review and meta-analysis of resveratrol for spinal cord injury in animal models
Resveratrol shows promise for spinal cord injury in animal studies
This systematic review and meta-analysis of 38 preclinical animal studies found that resveratrol significantly improved locomotor recovery a…
A review of animal studies suggests resveratrol may improve movement and reduce damage after spinal cord injury, but human trials are needed…
Case report details vitamin B12 treatment for nitrous oxide induced neurological damage
Nitrous oxide linked to lasting brain fog and nerve damage
This case report describes a patient with protracted encephalopathy associated with nitrous oxide use who received vitamin B12 supplementati…
Chronic nitrous oxide use can cause lasting brain fog and nerve damage, and a new case report shows vitamin B12 may help but long-term plans…
Case report and review of TTMV::RARA-positive APL with spinal cord compression in a child
Doctors treated a boy with rare leukemia and spinal pressure using special drugs
This is a case report with a systematic review of 11 published cases of TTMV::RARA-positive acute promyelocytic leukemia (APL). The authors …
A nine-year-old boy had rare leukemia and spinal cord pressure. Doctors used specific drugs that helped clear the disease and fix his spine.
Systematic review and meta-analysis links injury severity and infection to hyponatremia in acute spinal cord injury patients
Spinal injury patients face higher hyponatremia risk with certain factors
This systematic review and meta-analysis evaluated factors associated with hyponatremia in 2,355 patients with acute spinal cord injury. The…
A major review found that specific injury types and infections raise the chance of low sodium in spinal cord patients. Targeted monitoring i…
Narrative review explores ferroptosis-immune crosstalk in CNS diseases as therapeutic target
New hope for brain diseases by targeting a deadly cell death cycle
This narrative review synthesizes evidence on the interplay between ferroptosis and immune responses in CNS disorders including Alzheimer's,…
Scientists found a way to stop a deadly cell death cycle that makes brain diseases worse, offering new hope for patients with Alzheimer's an…
Case report and literature review of thymoma associated with stiff person syndrome and myasthenia gravis
A Rare Muscle Stiffness Link to Thymoma Tumor Explained
This case report and literature review examines the association between thymoma and autoimmune syndromes including stiff person syndrome and…
A rare mix of muscle stiffness and weakness was traced to a thymoma tumor, with new genetic clues pointing to a shared immune cause.
Systematic review and meta-analysis links prior flap reconstruction and injury level to pressure injury recurrence in SCI patients
Prior flap surgery raises complication risk for spinal cord injury patients
This systematic review and meta-analysis evaluated risk factors for acute postoperative complications and pressure injury recurrence in 1976…
Past flap reconstruction surgery significantly increases the risk of complications and pressure injury recurrence for spinal cord injury pat…
Earlier salivary melatonin onset associated with respiratory symptoms in early amyotrophic lateral sclerosis
Sleep Timing Could Predict Survival in Early ALS
This prospective longitudinal observational study assessed salivary dim-light melatonin onset in 50 people living with amyotrophic lateral s…
New research suggests sleep timing predicts how fast ALS gets worse and who survives longer without extra help.
Network meta-analysis compares pharmacological and biological therapies for amyotrophic lateral sclerosis
New ALS Therapy Combo Shows Promise For Slowing Functional Decline
This network meta-analysis synthesized data from 109 trials involving 16,353 participants to evaluate pharmacological and biological therapi…
A major analysis suggests combining cell therapy with neuroprotective drugs may help ALS patients maintain physical function longer, though …
Reeldesemtiv showed no impact on device use in ALS trial terminated early for futility
Wheelchair access varies wildly, and drug trial ended early without benefit for ALS patients
This Phase 3 randomized clinical trial enrolled 482 participants with amyotrophic lateral sclerosis (ALS) across 83 sites.
Access to wheelchairs differs greatly by region, and a major drug trial for ALS stopped early because it did not help patients.
All Spinal cord disorders Articles
- Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
- Systematic review of neural progenitor cell transplantation for spinal cord injury
- Systematic review and meta-analysis of resveratrol for spinal cord injury in animal models
- Case report details vitamin B12 treatment for nitrous oxide induced neurological damage
- Case report and review of TTMV::RARA-positive APL with spinal cord compression in a child
- Systematic review and meta-analysis links injury severity and infection to hyponatremia in acute spinal cord injury patients
- Case report and literature review of thymoma associated with stiff person syndrome and myasthenia gravis
- Narrative review explores ferroptosis-immune crosstalk in CNS diseases as therapeutic target
- Systematic review and meta-analysis links prior flap reconstruction and injury level to pressure injury recurrence in SCI patients
- Earlier salivary melatonin onset associated with respiratory symptoms in early amyotrophic lateral sclerosis
- Network meta-analysis compares pharmacological and biological therapies for amyotrophic lateral sclerosis
- Reeldesemtiv showed no impact on device use in ALS trial terminated early for futility
- Secondary analysis of pooled ALS trial data reveals entropy-based functional domain trajectories
- Early transanal irrigation improves constipation and independence in spinal cord injury patients
- Retrospective study links SMA type 1 to higher hip instability prevalence in children
- Meta-analysis finds rTMS improves neuropathic pain in spinal cord injury patients
- Systematic review and meta-analysis of Danshen for spinal cord injury in animal models
- Narrative review discusses exosomes for spinal cord injury without reported outcomes or safety data
- Cross-sectional CSF proteomic analysis identifies ALS-specific biomarker signature
- Masitinib 4.5 mg/kg/day associated with survival in ALS post-hoc analysis
- Meta-analysis links speech features to severity in Parkinsons, cerebral palsy, and ALS
- Systematic review finds gut microbiome dysbiosis associated with ALS progression
- Observational study finds no association between ZFHX3 GGC repeat expansions and ALS risk
- REDDI pipeline improves balanced accuracy for classifying MCI, MS, Parkinson's, and ALS using MEG data
- Systematic review validates iPSC-derived organoids as models for ALS pathology compared to traditional 2D or animal models
- Canadian policies for spinal cord injury supplies vary widely, often relying on means-testing rather than medical need
- Pilot RCT finds Cognitive Multisensory Rehabilitation may improve sensorimotor function in spinal cord injury
- Muscle ultrasonography shows high diagnostic accuracy for fasciculation detection in ALS
- Narrative review examines autonomic modulation strategies for spinal cord injury recovery
- FDG-PET reveals dysregulated glucose metabolism as a common feature across late-onset neurodegenerative diseases with unique patterns
- Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury
- First-in-human case study of BCI-spinal stimulation shows hand function gains in chronic tetraplegia
- Spinal cord injury linked to altered cortical excitability response to repeated tDCS
- Hypnotic cognitive therapy reduces pain intensity in adults with spinal cord injury
- Spinal cord ischemia recovery after TAAA repair improves from 35% at 3 months to 63% at 24 months
- Meta-analysis finds no significant association between statin use and ALS survival outcomes