Meta-analysis finds frozen section reliable for tumor-free margins in OSCC
Surgeons rely on frozen sections to ensure clean cuts for oral cancer patients
This systematic review and meta-analysis of 19 studies (9 with complete data) assessed frozen section analysis for detecting tumor-free marg…
A new review confirms that frozen section analysis is a highly reliable way for surgeons to check if oral cancer has been fully removed duri…
SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer
Combination therapy improves survival in older esophageal cancer patients
This phase III multicenter RCT compared simultaneous integrated boost radiotherapy plus oral S-1 (CRTCT) to radiotherapy alone in patients a…
Adding chemo to radiation boosts 5-year survival from 24% to 34% in older patients with inoperable esophageal cancer.
Review of multimodal deep learning model for esophageal squamous cell carcinoma diagnosis
New AI tool spots esophageal cancer early with expert accuracy
This review synthesizes a model development and validation study for esophageal squamous cell carcinoma.
A new AI system matches expert doctors in spotting early esophageal cancer. This could change how patients get diagnosed.
Review of PBMC processing conditions in head and neck squamous cell carcinoma treatment-naive patients
New blood test method avoids risky biopsies for cancer patients
This observational study review examines peripheral blood mononuclear cell (PBMC) processing conditions for treatment-naive patients with he…
A new blood processing method lets doctors track immune health without risky biopsies for head and neck cancer patients.
Narrative review discusses targeting ferroptosis and cuproptosis in oral squamous cell carcinoma
New ideas target cell death pathways for oral cancer
This narrative review explores the potential of targeting ferroptosis and cuproptosis in patients with oral squamous cell carcinoma.
A review explores fresh ways to fight oral cancer by targeting specific cell death pathways. This approach offers new hope for patients with…
Deep learning segmentation with CT elasticity features predicts right recurrent laryngeal nerve metastasis in esophageal cancer
AI Can Spot Hidden Cancer Spread in the Neck Before Surgery
This retrospective cohort study of 415 patients with esophageal squamous cell carcinoma evaluated a deep learning-based segmentation model w…
This research could help surgeons avoid damaging a vital nerve during esophageal cancer surgery, making operations safer and more precise.
Iron and oxidative stress biomarkers linked to oral cancer recurrence after surgery
Iron levels and oxidative stress linked to cancer return in oral squamous cell carcinoma patients
This retrospective cohort study of 240 patients with oral squamous cell carcinoma who underwent radical surgery found that 36.7% experienced…
Among 240 oral cancer patients, high iron and oxidative stress markers were more common in those whose cancer came back after surgery.
Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
Combination therapy may help overcome resistance in esophageal cancer
This Phase 3 RCT in 55 patients with locally advanced esophageal squamous cell carcinoma compared neoadjuvant chemotherapy alone versus comb…
A small trial suggests combination therapy might help overcome resistance in esophageal cancer by targeting specific immune cells.
Personalized swallowing rehab improves outcomes after oral cancer surgery
New Swallowing Therapy Helps Oral Cancer Patients Eat and Speak More Easily
This randomized controlled trial in 300 patients with oral squamous cell carcinoma found that a personalized swallowing rehabilitation progr…
Personalized swallowing therapy helps oral cancer patients recover faster, eat more naturally, and avoid dangerous complications like pneumo…
High NSUN3 expression linked to poor survival in oral squamous cell carcinoma
High NSUN3 protein makes oral cancer spread faster
This cohort study of 60 oral squamous cell carcinoma patients found that upregulated NSUN3 expression is an independent risk factor for poor…
Imagine waking up with a sore in your mouth that won't heal.
Becotatug vedotin shows 20.9% objective response in recurrent head and neck squamous cell carcinoma after prior therapy
For patients with advanced head and neck cancer, a new drug showed a 21% response rate in early testing
This multicenter, Phase IIa trial evaluated intravenous becotatug vedotin in 67 patients with recurrent or metastatic squamous cell carcinom…
A new drug shrank tumors in 21% of patients with advanced head and neck cancer who had run out of standard treatment options.
Review links oral microbiome dysbiosis to malignant transformation in oral lichen planus
Bacteria That Turn Harmful Mouth Sores Into Cancer
This narrative review synthesizes evidence regarding oral microbiome dysbiosis as a potential driver of malignant transformation in oral lic…
Changing the bad bacteria in your mouth could stop a painful sore from becoming cancer.