Routine lab indicators help differentiate typical from incomplete Kawasaki disease and predict coronary lesions
Lab indicators may help identify Kawasaki disease risks
This retrospective study of 131 children with Kawasaki disease found that total protein was the only independent factor differentiating typi…
Routine blood markers could help doctors better identify Kawasaki disease types and predict potential heart complications in children.
Genetic burden in PI3K–AKT–mTOR pathway linked to microscopic polyangiitis susceptibility in Chinese cohort
Genetic markers linked to higher risk of microscopic polyangiitis in Chinese patients
This observational cohort study in a Chinese population examined genetic burden across the PI3K–AKT–mTOR pathway and susceptibility to micro…
A specific genetic load tied to a key cell pathway raises the risk of microscopic polyangiitis, offering new clues for prevention and care.
Machine-learning model predicts coronary artery lesions in Kawasaki disease
Kids with rare heart condition may get faster help
This retrospective cohort study from a Chinese hospital developed a CatBoost machine-learning model to predict coronary artery lesions in Ka…
This tool could help doctors spot which kids face the highest risk of heart damage from Kawasaki disease — before it happens.
Prednisolone plus standard treatment did not significantly reduce coronary-artery lesions in newly diagnosed Kawasaki disease patients
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients
This multicenter, open-label, randomized, controlled trial evaluated 3208 participants with newly diagnosed Kawasaki disease in China.
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients, as lesion rates remained nearly the same.
Systematic review evaluates anti-IL-5 and anti-IL-5Rα biologics for eosinophilic respiratory and systemic diseases
New Asthma Drugs Target the Real Troublemakers Hiding in Your Lungs
This systematic review examined the use of anti-IL-5 and anti-IL-5Rα biologics in patients with severe eosinophilic asthma, chronic rhinosin…
New asthma drugs target the specific immune cells causing swelling and mucus in severe asthma, nasal polyps, and rare eosinophil diseases.
Infliximab in IVIG-resistant Kawasaki disease with cholestatic hepatitis: case report
Can a new drug stop heart damage in Kawasaki disease when standard treatments fail?
A case report describes a 2-year-old Han Chinese male with IVIG-resistant Kawasaki disease and cholestatic hepatitis treated with infliximab…
In a two-year-old boy with Kawasaki disease, the drug infliximab quickly stopped his fever and liver trouble, yet his heart artery damage ke…
Expert review outlines diagnostic and therapeutic management strategies for eosinophilic granulomatosis with polyangiitis
Rare Lung and Blood Disease Gets a Smarter Treatment Map
This expert review addresses the management of patients with eosinophilic granulomatosis with polyangiitis (EGPA), focusing on glucocorticoi…
A new expert roadmap shifts treatment for rare EGPA disease from steroids to targeted biologic drugs for patients with stubborn asthma and o…
Surgical resection associated with spontaneous remission in Toxocariasis-linked vasculitis case
A Common Parasite May Be Quietly Triggering Autoimmune Disease
A systematic review of a single case report describes a 45-year-old woman with Toxocariasis-associated small-vessel vasculitis.
A common roundworm infection may trigger serious autoimmune blood vessel inflammation, offering a potential cure for unexplained rashes and …
ANCA-associated vasculitis associated with higher mortality and cardiovascular events in retrospective cohort analysis
New data links rare blood vessel diseases to higher death and heart risks
This retrospective cohort study analyzed 20,422 patients with granulomatosis with polyangiitis and 5,907 with microscopic polyangiitis using…
People with rare blood vessel diseases face nearly three times the death risk and higher heart attack rates compared to healthy people.
Meta-analysis finds 7% incidence of suspected carotid atheromas on dental panoramic radiographs
Dental X-rays May Show Calcified Artery Plaque in Some Patients
This systematic review and meta-analysis of 34 cross-sectional studies in dental practice synthesizes evidence on calcified carotid artery a…
About 7% of dental X-rays show signs of artery plaque, meaning routine scans might reveal hidden heart risks that need medical attention.
Meta-analysis of DOACs versus conventional anticoagulation in Kawasaki disease with giant coronary artery aneurysms
Simpler Blood Thinners May Protect Kids' Damaged Heart Arteries
This systematic review and meta-analysis evaluated 594 children younger than 19 years with Kawasaki disease-associated giant coronary artery…
Children with the most serious heart complication of Kawasaki disease may soon swap daily shots for a once-a-day pill, with no drop in safet…
Therapeutic plasma exchange in pediatric autoimmune diffuse alveolar hemorrhage shows 5 of 6 survival
Kids' Lungs Bleeding: Early Blood Swap Saves Lives
A retrospective cohort study of 6 pediatric patients with autoimmune diffuse alveolar hemorrhage requiring intensive care found that therape…
Early blood swaps saved six critically ill children with autoimmune lung bleeding, avoiding death in all cases treated with this urgent ther…