Tirofiban plus aspirin associated with lower early neurological deterioration in branch atheromatous disease
Early tirofiban plus aspirin linked to fewer early neurological declines in branch atheromatous disease patients
A retrospective single-center cohort study in patients with acute branch atheromatous disease found early tirofiban plus aspirin was associa…
Early tirofiban plus aspirin reduced early neurological decline from 55.1% to 10.1% in branch atheromatous disease patients compared to stan…
Lp-PLA2 activity does not significantly modify dual antiplatelet therapy efficacy in minor stroke/TIA with CYP2C19 loss-of-function alleles
Blood enzyme levels don't change which stroke prevention drug works better, study finds
This subgroup analysis of the CHANCE-2 RCT examined 5919 patients with minor stroke/TIA and CYP2C19 loss-of-function alleles. Lp-PLA2 activi…
A simple blood test for inflammation doesn't predict which stroke prevention drug works best for patients with a specific genetic trait.
Protocol for argatroban plus clopidogrel versus aspirin plus clopidogrel in acute minor ischemic stroke
Study will compare two blood thinner combinations for minor strokes
This is a study protocol for a randomized controlled trial of 464 patients with acute minor ischemic stroke (NIHSS ≤5) within 72 hours. It w…
A new trial will test if adding argatroban to clopidogrel leads to better recovery than aspirin plus clopidogrel for minor stroke patients.
Post hoc analysis finds cilostazol reduces stroke recurrence without lowering systolic blood pressure
Study finds cilostazol reduces stroke recurrence without lowering blood pressure
A post hoc mediation analysis of an RCT in 1,795 patients with noncardioembolic ischemic stroke found dual therapy with cilostazol plus aspi…
Cilostazol lowers stroke recurrence risk in patients with prior noncardioembolic strokes without working by dropping their blood pressure.
Adjuvant NSAIDs associated with improved DFS in resected PIK3CA-mutated colorectal cancer
NSAID therapy after surgery may help prevent colorectal cancer recurrence in some patients
A meta-analysis of 789 patients with resected PIK3CA-mutated colorectal cancer found adjuvant NSAID therapy (aspirin or COX-2 inhibitors) wa…
Taking anti-inflammatory drugs like aspirin after colorectal cancer surgery may lower the risk of the cancer returning in patients with a sp…