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Anesthesiology & Pain Medicine
Meta-analysis
External Oblique Intercostal Plane Block reduces postoperative opioid consumption by 19.55 mg compared to standard analgesia
New nerve block reduces opioid use after abdominal surgery
This meta-analysis of 899 adults undergoing thoracoabdominal surgery found that the External Oblique Intercostal Plane Block (EOIPB) signifi…
A specific nerve block technique significantly lowers the amount of opioids patients need during recovery from complex abdominal surgeries.
Aug 4, 2026
Anesthesiology & Pain Medicine
RCT
Opioid Safety Toolkit increases naloxone requests (OR 2.5) and overdose knowledge compared to standard information
Interactive safety tools help patients request life-saving overdose medication
This randomized controlled trial of 314 adults prescribed opioids for non-cancer pain found that an interactive Opioid Safety Toolkit increa…
A new interactive safety toolkit significantly increased the number of patients requesting naloxone to combat opioid overdose risks.
Aug 4, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Opioids provide clinically important pain relief for short durations but lack long-term efficacy in osteoarthritis
Opioids provide short term relief for chronic back pain
This meta-analysis of 27 trials evaluated opioid use for chronic low back pain and osteoarthritis. Findings indicate opioids are more likely…
Opioids may offer meaningful pain relief for back issues in the first month, but their effectiveness drops off significantly after 12 weeks.
Aug 4, 2026
Diabetes & Endocrinology
Sys. Review
External oblique intercostal block provides greatest opioid-sparing effect for laparoscopic sleeve gastrectomy patients
Specific nerve blocks may reduce opioid use after weight loss surgery
This network meta-analysis of 2,005 adults undergoing laparoscopic sleeve gastrectomy found that the external oblique intercostal (EOI) bloc…
New research suggests specific regional nerve blocks can significantly lower morphine needs and nausea for patients undergoing stomach sleev…
Aug 1, 2026
Orthopedics & Sports Medicine
Meta-analysis
ERAS pathways may reduce opioid exposure and shorten hospital stays in flap reconstruction
ERAS Pathways May Reduce Opioid Use in Reconstruction Surgery
This structured narrative review synthesizes the impact of ERAS protocols on outcomes for patients undergoing flap-based reconstruction. The…
Newer recovery pathways may help patients undergoing flap reconstruction get home sooner while reducing their exposure to opioid medications…
Frontiers
Jul 30, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Epidural analgesia may reduce pain during movement after laparoscopic abdominal surgery compared to PCIA
Epidural Analgesia May Reduce Pain After Abdominal Surgery
This systematic review and meta-analysis of 34 studies for quantitative analysis indicates that epidural analgesia may slightly reduce pain …
Epidural analgesia might lower pain levels after abdominal surgery, but it may also cause common side effects like low blood pressure.
Jul 24, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Percutaneous Cervical Cordotomy reduces pain and opioid consumption in patients with severe cancer pain
Procedure Shows Relief for Severe Treatment Resistant Cancer Pain
This meta-analysis of randomized controlled trials evaluates percutaneous cervical cordotomy (PCC) for managing treatment-resistant cancer p…
A surgical procedure called percutaneous cervical cordotomy may reduce severe cancer pain and lower the amount of opioids needed by patients…
Jul 8, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Intercostal nerve cryoablation reduces inpatient opioid consumption by 102 morphine milligram equivalents
Cryoablation reduces opioid use after thoracic and cardiac surgery
This meta-analysis of 18,465 patients undergoing non-pectus repair thoracic or cardiac procedures found that intercostal nerve cryoablation …
A new analysis shows that freezing specific nerves before chest surgery can significantly lower the amount of opioid pain medication patient…
Jun 13, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Systematic review finds ketamine offers no pain advantage over opioids in prehospital trauma care settings
Ketamine works as well as opioids for trauma pain
Analysis of eighteen studies shows ketamine provides similar pain relief to opioids for trauma patients. While heart rate rose slightly, adv…
For traumatic injuries, ketamine relieves pain just as well as opioids, with a modest heart rate increase.
Jun 1, 2026
Emergency Medicine
Sys. Review
ERAS protocols may reduce opioid use and shorten stays for patients undergoing orthognathic surgery
ERAS protocols show promise for orthognathic surgery recovery
This narrative review examines the application of Enhanced Recovery After Surgery (ERAS) protocols in orthognathic surgery. The authors synt…
Enhanced Recovery After Surgery protocols may reduce opioid use and shorten hospital stays for patients undergoing jaw surgery.
Frontiers
May 30, 2026
Rheumatology
Meta-analysis
Meta-analysis shows VR reduces pain in adult ICU patients receiving conventional care
Virtual reality headsets lower pain scores for adults in the ICU
This meta-analysis and systematic review evaluated virtual reality technology in adult ICU patients. The analysis pooled data from 979 patie…
A review of five studies found that virtual reality headsets with nature scenes significantly reduced pain scores for adults in the ICU.
Frontiers
May 19, 2026
Geriatrics & Aging
Cohort
Hybrid NLP and LLM system extracts deprescribing recommendations from electronic health records for older hospitalized patients
New tool helps doctors stop unnecessary drugs for older hospital patients
This retrospective cohort study evaluated a two-stage hybrid system combining rule-based natural language processing and open-source large l…
A new computer system accurately finds advice to stop antibiotics and painkillers for older adults. This helps hospitals reduce risky medici…
medRxiv
May 1, 2026