Percutaneous Cervical Cordotomy reduces pain and opioid consumption in patients with severe cancer pain
Procedure Shows Relief for Severe Treatment Resistant Cancer Pain
This meta-analysis of randomized controlled trials evaluates percutaneous cervical cordotomy (PCC) for managing treatment-resistant cancer p…
A surgical procedure called percutaneous cervical cordotomy may reduce severe cancer pain and lower the amount of opioids needed by patients…
Intercostal nerve cryoablation reduces inpatient opioid consumption by 102 morphine milligram equivalents
Cryoablation reduces opioid use after thoracic and cardiac surgery
This meta-analysis of 18,465 patients undergoing non-pectus repair thoracic or cardiac procedures found that intercostal nerve cryoablation …
A new analysis shows that freezing specific nerves before chest surgery can significantly lower the amount of opioid pain medication patient…
Systematic review finds ketamine offers no pain advantage over opioids in prehospital trauma care settings
Ketamine works as well as opioids for trauma pain
Analysis of eighteen studies shows ketamine provides similar pain relief to opioids for trauma patients. While heart rate rose slightly, adv…
For traumatic injuries, ketamine relieves pain just as well as opioids, with a modest heart rate increase.
ERAS protocols may reduce opioid use and shorten stays for patients undergoing orthognathic surgery
ERAS protocols show promise for orthognathic surgery recovery
This narrative review examines the application of Enhanced Recovery After Surgery (ERAS) protocols in orthognathic surgery. The authors synt…
Enhanced Recovery After Surgery protocols may reduce opioid use and shorten hospital stays for patients undergoing jaw surgery.
Meta-analysis shows VR reduces pain in adult ICU patients receiving conventional care
Virtual reality headsets lower pain scores for adults in the ICU
This meta-analysis and systematic review evaluated virtual reality technology in adult ICU patients. The analysis pooled data from 979 patie…
A review of five studies found that virtual reality headsets with nature scenes significantly reduced pain scores for adults in the ICU.
Hybrid NLP and LLM system extracts deprescribing recommendations from electronic health records for older hospitalized patients
New tool helps doctors stop unnecessary drugs for older hospital patients
This retrospective cohort study evaluated a two-stage hybrid system combining rule-based natural language processing and open-source large l…
A new computer system accurately finds advice to stop antibiotics and painkillers for older adults. This helps hospitals reduce risky medici…
Narrative review discusses perioperative local anesthetics and regional anesthesia in cancer care
Local Anesthetics May Slow Cancer Spread
This narrative review examines the role of perioperative local anesthetics and regional anesthesia compared to opioids within comprehensive …
Using local anesthesia instead of just opioids during surgery might help stop cancer from spreading after the operation.
Narrative review contrasts pediatric and adult pain management in emergency settings
ER Doctors Are Rethinking Pain Care for Kids vs Adults
This narrative review synthesizes global emergency department pain management strategies for pediatric versus adult patients.
It starts with a child clutching a broken arm.
In a cohort of 561 individuals with chronic pain, sex and gender identity influenced repeated prescription refill odds
Your Pain Meds May Depend on Who You Are, Not Just What Hurts
This observational cohort study examined 561 individuals living with chronic pain using public and private prescription claims data over one…
Chronic pain treatment isn’t one-size-fits-all; new research shows your personal identity plays a major role in the prescriptions you receiv…
Systematic Review Analyzes Pharmacometric Modeling of Opioids and Fentanyl in Pregnancy
Opioid Dosing in Pregnancy May Need a Rethink
This systematic review evaluates pharmacometric modeling approaches, including population pharmacokinetic and physiologically based pharmaco…
Pregnancy speeds up how the body processes pain meds, meaning standard doses may leave moms in pain or risk baby safety.
Report estimates state-level economic costs of opioid use disorder and fatal overdose
Report estimates state-level economic costs of opioid use disorder and overdose
A report estimated state-level economic costs of opioid use disorder and fatal opioid overdose in the United States.
A new report estimates the economic costs of opioid use disorder and fatal overdoses for every state in the United States in 2017.
Case series identifies 38 medetomidine-involved opioid overdoses in Chicago
Chicago health officials identify overdoses involving veterinary sedative mixed with opioids
A case series in Chicago identified 38 individuals with medetomidine-involved opioid overdoses (12 confirmed, 26 probable).
Chicago officials warn that a veterinary sedative is now mixed with opioids in street drugs, causing 38 overdoses in the city.