Epigallocatechin-3-gallate shows positive therapeutic effects on various digestive system diseases in animal models
Green tea compound shows potential for several digestive diseases
This meta-analysis of 63 preclinical studies involving 738 animals indicates that Epigallocatechin-3-gallate (EGCG) has a positive therapeut…
A review of animal studies suggests a green tea compound could help treat various cancers and digestive conditions.
HLA-B*57:01-guided abacavir prescribing is the clearest preventive paradigm from HLA associations
HLA genes shape HIV and hepatitis vaccine responses and drug reactions
This narrative review examines HLA polymorphisms in HIV, hepatitis C, and hepatitis B. The clearest preventive paradigm is HLA-B*57:01-guide…
A review finds that HLA genes strongly influence how people respond to HIV and hepatitis vaccines and how they react to certain medications.
Chronic HCV infection drives T cell dysfunction, regulatory T cell accumulation, and metabolic defects that persist after viral clearance
Immune defects in hepatitis C may last after the virus is gone
This narrative review examines immune mechanisms in patients with chronic hepatitis C virus infection. The authors describe how prolonged an…
A review explains how chronic hepatitis C causes lasting immune changes that persist even after the virus is cleared, suggesting new treatme…
One in six blood donors in Cameroon carries Plasmodium infection, meta-analysis finds
1 in 6 blood donors in Cameroon carries malaria parasite
A systematic review and meta-analysis of 18 studies (~12,500 donations) found a 16.6% pooled prevalence of Plasmodium spp. in Cameroonian bl…
A review of 18 studies finds 16.6% of blood donations in Cameroon contain Plasmodium, the malaria parasite.
Narrative review on ICIs in patients with viral infections and solid tumors
Cancer Immunotherapy Works Differently in Viral Infections
This narrative review synthesizes evidence on immune checkpoint inhibitors in patients with viral infections and solid tumors.
Cancer immunotherapy can still work—and sometimes even control viruses like hepatitis or HIV—but doctors must watch for dangerous flare-ups.
Meta-analysis of 55 studies assesses HCV prevalence trends across Eastern Mediterranean Region populations
HCV Rates Drop in High-Risk Groups After 2015
This umbrella review synthesizes data from 55 meta-analyses evaluating hepatitis C virus (HCV) prevalence in the Eastern Mediterranean Regio…
Imagine walking into a doctor's office and feeling a knot of worry in your stomach.
Randomized trial shows ribavirin increases mutational load and specific transition signatures in HCV
Ribavirin linked to increased hepatitis C virus mutations in trial
This secondary analysis of a randomized trial in HCV-infected participants found ribavirin exposure significantly increased total mutational…
Ribavirin treatment linked to increased hepatitis C virus mutations in a trial, though real-world impact on cure rates remains unclear.
Meta-analysis of 9 studies estimates HCV seroprevalence of 3.63% among African refugees and displaced persons
Hidden Virus Threats Among Displaced People
This systematic review and random-effects meta-analysis of 9 studies estimated hepatitis C virus (HCV) seroprevalence among refugees, asylum…
A new look at data shows hepatitis C is very common among refugees and displaced people in Africa, where they often face huge barriers to ge…
Machine learning models predict SVR in comorbid HCV patients treated with sofosbuvir, daclatasvir, and ribavirin in Pakistan
Can a computer predict your hepatitis C cure?
This retrospective cohort study evaluated machine learning prediction models in 221 comorbid HCV patients in Pakistan.
A new computer tool can spot which hepatitis C patients are likely to fail treatment before they even start taking pills.
Global acute hepatitis C incidence declined overall but increased after 2015, analysis shows
Is hepatitis C making a comeback? Global cases rose after 2015
An observational cohort analysis of global and Chinese populations from 1990 to 2021 found the global age-standardized incidence rate (ASIR)…
Global hepatitis C infections rose after 2015, reversing years of progress and creating a new public health challenge that experts must addr…
CDC issues new guidance for completing hepatitis C virus testing
CDC updates guidance for completing hepatitis C testing to improve diagnosis
The CDC has published new guidance for completing hepatitis C virus testing.
The CDC released new guidance to help healthcare providers complete hepatitis C testing steps to confirm diagnoses.
CDC Recommends Universal Hepatitis C Screening for Adults and All Pregnant Women
Should all adults get tested for hepatitis C? New guidelines say yes
The CDC has issued new recommendations for hepatitis C screening.
CDC now recommends a one-time hepatitis C blood test for all adults and screening for every pregnant woman to catch hidden infections early.
Research across Hepatitis
Related studies from across the Hepatitis family.
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
PEG-IFN plus novel agents may boost functional cure in chronic hepatitis B
Combination therapies may improve functional cure rates for chronic hepatitis B
This narrative review examines combining pegylated interferon-α with novel immunotherapies (antigen-reduction strategies, therapeutic vaccin…
A review suggests combining pegylated interferon with new immunotherapies could help achieve functional cure in chronic hepatitis B patients…
Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
New antiviral strategies show promise for chronic hepatitis B infection
This narrative review synthesizes evidence on antiviral and immunotherapeutic strategies for chronic hepatitis B. The authors highlight func…
A review of new treatments suggests combination therapies may offer future value for managing chronic hepatitis B, cirrhosis, and liver canc…
Meta-analysis identifies genetic variants linked to HBV susceptibility and HCC risk
Genetic Keys Unlock Why Some Get Liver Cancer From Hepatitis B
This meta-analysis of East Asian cohorts examined genetic variants associated with hepatitis B virus infection and hepatocellular carcinoma …
New research shows specific gene changes help explain why some people get Hepatitis B while others stay healthy.
Systematic review and meta-analysis of biopsy-guided versus clinically guided withdrawal in autoimmune hepatitis
Biopsy-guided withdrawal shows no benefit over clinical guidance for autoimmune hepatitis
This systematic review and meta-analysis evaluated relapse rates after treatment withdrawal in patients with autoimmune hepatitis.
A meta-analysis of 518 patients found that biopsy-guided withdrawal did not lower relapse rates compared to clinically guided withdrawal in …
HEV 239 vaccine induces durable humoral and cellular immunity in Bangladeshi women
Hepatitis E vaccine shows durable immunity in women
This longitudinal cohort study in 1480 women aged 16-39 years in Bangladesh found that HEV 239 (Hecolin) vaccination led to significantly hi…
A hepatitis E vaccine kept women protected for up to 3 years, with stronger immune memory than a comparison group.
Pegylated interferon alpha associated with HBsAg clearance in postpartum women with chronic HBV infection
New treatment clears hepatitis B in 3 out of 10 women after childbirth
This prospective cohort study evaluated 263 postpartum women with chronic hepatitis B virus infection and baseline HBsAg levels ≤3000 IU/mL.
A new treatment clears hepatitis B markers in nearly 30% of women after childbirth, offering fresh hope for a functional cure during a uniqu…
Hepatic steatosis prevalence and impact in autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis
Fatty liver makes autoimmune hepatitis and PBC worse, but not PSC
This systematic review and meta-analysis of 19,898 patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing c…
A large review found fatty liver is common in autoimmune liver diseases and makes outcomes worse for some patients, but not others.
Absence of antiviral therapy and multiple chemotherapeutic agents increase HBV reactivation risk after TACE
No Antiviral Meds Raise Liver Cancer Risks After Chemo
This retrospective cohort study of 168 HBsAg-positive HCC patients undergoing TACE found that absence of prophylactic antiviral therapy (OR …
Many liver cancer patients with hepatitis B face avoidable risks during chemo—because they’re not getting a simple antiviral pill most alrea…
HBV-positive status linked to higher surgical conversion in unresectable HCC receiving triple therapy
HBV-positive linked to better outcomes in liver cancer triple therapy
This single-center retrospective cohort study evaluated triple therapy with TACE, lenvatinib, and PD-1 inhibitors in 190 patients with initi…
In unresectable liver cancer, triple therapy with TACE, lenvatinib, and PD-1 inhibitors worked better in HBV-positive patients, a small retr…
Integrative review of Epimedium flavonoids in hepatitis and cirrhosis shows preclinical promise but lacks clinical validation
Ancient Herb Shows New Promise for Liver Scarring and Hepatitis
This integrative review synthesizes data from 33 high-impact studies regarding Epimedium species and its bioactive flavonoids, icariin and i…
This research suggests a traditional herb may offer a new way to protect the liver, but more work is needed to prove it’s safe and effective…
Narrative review synthesizes evidence on NAFLD, NASH, and viral hepatitis management without reported trial data
Your Liver Has an Immune Army — and It Can Turn Against You
This narrative review addresses management considerations for nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH),…
Your liver's own immune cells can turn on itself to cause permanent scarring, but scientists are now mapping these cells to stop the damage …
Questions about Hepatitis C
How should healthcare workers follow up after an acute Hepatitis C Virus infection?
Healthcare workers with acute HCV should undergo baseline and serial HCV RNA testing, with follow-up for at least 6 months to confirm clearance or initiate treatment.
Full answer →Why is the CDC recommending universal screening for Hepatitis C for pregnant women?
The CDC recommends universal Hepatitis C screening for all pregnant women because infection rates have doubled in the US since 2009, many cases go undiagnosed, and screening is now considered cost-effective.
Full answer →Does taking ribavirin for Hepatitis C cause more genetic mutations in the virus?
Yes, ribavirin increases genetic mutations in HCV, as shown by a randomized trial that found higher mutational load and specific nucleotide changes in the virus.
Full answer →How has the rate of Hepatitis C changed among younger adults in the US?
Hepatitis C rates have increased dramatically among younger US adults, driven by the opioid epidemic and injection drug use.
Full answer →All Hepatitis C Articles
- Epigallocatechin-3-gallate shows positive therapeutic effects on various digestive system diseases in animal models
- HLA-B*57:01-guided abacavir prescribing is the clearest preventive paradigm from HLA associations
- Chronic HCV infection drives T cell dysfunction, regulatory T cell accumulation, and metabolic defects that persist after viral clearance
- One in six blood donors in Cameroon carries Plasmodium infection, meta-analysis finds
- Narrative review on ICIs in patients with viral infections and solid tumors
- Meta-analysis of 55 studies assesses HCV prevalence trends across Eastern Mediterranean Region populations
- Randomized trial shows ribavirin increases mutational load and specific transition signatures in HCV
- Meta-analysis of 9 studies estimates HCV seroprevalence of 3.63% among African refugees and displaced persons
- Machine learning models predict SVR in comorbid HCV patients treated with sofosbuvir, daclatasvir, and ribavirin in Pakistan
- Global acute hepatitis C incidence declined overall but increased after 2015, analysis shows
- Updated guidance for hepatitis C virus exposure and acute infection in healthcare personnel
- Hepatitis C cases increasing dramatically in US population, especially among younger adults
- CDC Recommends Universal Hepatitis C Screening for Adults and All Pregnant Women
- National trends show rising Hepatitis C and opioid use disorder rates in pregnant women at delivery
- Updated PHS guidelines recommend HIV, HBV, and HCV testing for pediatric transplant candidates under 12
- Hepatitis C treatment patterns examined in insured US adults
- CDC issues hepatitis C testing recommendations for perinatally exposed infants and children
- CDC issues new guidance for completing hepatitis C virus testing
- 8-week glecaprevir/pibrentasvir shows 96.2% SVR12 in acute HCV treatment-naïve adults
- HCV treatment with direct-acting antivirals linked to reduced alcohol use in people who inject drugs