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Home › Conditions › Cataract

Cataract

13 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Cataract

188 trials tracked for Cataract: 64 in phase 3 or 4 and 5 with published results. The most-cited published study has 281 citations.

188Trials tracked
64Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 33 Phase 3 31 Phase 2 9 Phase 1 2 Other / NA 113
  1. Phase 3 Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-1) Completed · 281 cited
  2. Phase 3 Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-2) Completed · 281 cited
  3. Phase 3 S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000 Completed · 50 cited
  4. Phase 3 Clinical Study of the Efficacy of the Ophthalmic Emulsion PRO-145 for Inflammation and Pain After Phacoemulsification Completed · 4 cited
  5. Phase 3 Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification. Completed · 3 cited
  6. Phase 4 Dropless vs. Standard Drops Contralateral Eye Study Completed
Show 44 more trials
  1. Phase 4 Sedation Methods During Cataract Surgery Completed
  2. Phase 4 Clinical Investigation of the Bi Flex M Multifocal IOL Completed
  3. Phase 4 Prophylactic Treatment: Lessdrops™ vs Standard Drops Regimen Completed
  4. Phase 4 Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL. Completed
  5. Phase 4 No Drop Post-Op Cataract Surgery Completed
  6. Phase 4 Symfony vs Vivity in Dim Light Completed
  7. Phase 4 Effects of Bromfenac on Macular Thickness After Phacoemulsification Surgery Completed
  8. Phase 4 In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery Completed
  9. Phase 4 A Real-world Study of DEXYCU in the Treatment of Inflammation After Cataract Surgery Completed
  10. Phase 4 Intraoperative Dexamethasone Implant Improves Outcome of Cataract Surgery With Diabetic Macular Edema Completed
  11. Phase 4 Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3 Completed
  12. Phase 4 Clinical Evaluation of a New Aspheric Intraocular Lens. Completed
  13. Phase 4 Intraoperative Floppy Iris Syndrome Completed
  14. Phase 4 Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens Completed
  15. Phase 4 Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction Completed
  16. Phase 4 A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs) Completed
  17. Phase 4 Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery Completed
  18. Phase 4 ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL) Completed
  19. Phase 4 A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at Kaduna, Nigeria Completed
  20. Phase 4 Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL Completed
  21. Phase 4 Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1 Completed
  22. Phase 4 Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA Completed
  23. Phase 4 Evaluation of 3 Intraocular Lenses Following Lens Extraction Completed
  24. Phase 4 A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms Completed
  25. Phase 4 Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL) Completed
  26. Phase 4 DisCoVisc Versus DuoVisc, Healon5 and AmVisc Plus Completed
  27. Phase 4 Presbyopia-Correcting Intraocular Lenses (IOLs) Completed
  28. Phase 4 Pharmacokinetic Evaluation of Moxifloxacin in Vigadexa® in Aqueous Humor Samples Following Preoperative Antibiotic/Steroid Dosing in Cataract Surgery Patients Completed
  29. Phase 4 A Comparison of Three Different Formulations of Prednisolone Acetate 1% Completed
  30. Phase 4 Co-Axial Micro-Incision Versus Co-Axial Small Incision Cataract Surgery Using the Stellaris Enhancement System Completed
  31. Phase 4 To Compare the Ability of DiscoVisc® OVD to Protect the Corneal Endothelium and Maintain Anterior Chamber Space With Healon® and Amvisc® PLUS During Cataract Surgery. Completed
  32. Phase 4 Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof Completed
  33. Phase 3 Nepafenac Once Daily for Macular Edema - Study 2 Completed
  34. Phase 3 Nepafenac Once Daily for Macular Edema - Study 1 Completed
  35. Phase 3 Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss Completed
  36. Phase 3 Study to Evaluate the Safety for the Treatment of Inflammation Associated With Cataract Surgery Completed
  37. Phase 3 Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children. Completed
  38. Phase 3 LE Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery Completed
  39. Phase 3 Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery Completed
  40. Phase 3 Mapracorat Ophthalmic Suspension for the Treatment of Ocular Inflammation Following Cataract Surgery Completed
  41. Phase 3 Loteprednol Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery Completed
  42. Phase 3 Loteprednol Etabonate Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery Completed
  43. Phase 3 Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery Completed
  44. Phase 3 Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery Completed

Showing the 50 most-cited and recently-updated of 188 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Review describes reverse optic capture technique for IOL fixation in complex cataract surgery
Ophthalmology Cohort
Review describes reverse optic capture technique for IOL fixation in complex cataract surgery Review describes reverse optic capture technique for complex cataract surgery cases
A review article describes the reverse optic capture (ROC) surgical technique for intraocular lens fixation in complex cataract surgery case…
Surgeons use reverse optic capture to fix lenses when the eye's back capsule breaks or lenses twist out of place.
Frontiers Apr 3, 2026

Questions about Cataract

How do smoking and aging affect my risk for cataract and macular degeneration?

Smoking and aging both increase your risk for cataract and macular degeneration, with smoking amplifying the age-related risk, especially after age 75.

Full answer →
Will a hybrid extended depth-of-focus lens improve my near vision?

Yes, hybrid extended depth-of-focus (EDF) lenses improve near vision compared to standard monofocal lenses, but near vision may not be as sharp as with multifocal lenses.

Full answer →
Which biomarkers are linked to my history of cataract surgery?

Inflammatory-nutrition biomarkers Ln-AISI, Ln-NAR, and Ln-MAR are linked to cataract surgery history, along with CRP, smoking, and aging.

Full answer →