Phase 3 trial of Ad5-nCoV vaccine shows no increased short-term HIV infection risk in 44,247 participants.
Ad5 COVID Vaccine Cleared of HIV Risk in 44,247-Person Trial
This Phase 3 randomized controlled trial evaluated the association between the Ad5-nCoV vaccine and HIV infection risk in 44,247 HIV-negativ…
A decades-old worry that certain vaccine delivery systems might raise HIV risk does not apply to the Ad5 COVID vaccine, based on a trial of …
Nirmatrelvir-ritonavir reduced viral production by approximately 55% in SARS-CoV-2 BA.2-infected patients in Shanghai.
Your COVID Pill May Work Better—Or Worse—Than You Think
This cohort study of 48,243 SARS-CoV-2 BA.2-infected patients in Shanghai evaluated nirmatrelvir-ritonavir exposure. The analysis indicated …
How well your Paxlovid works depends heavily on your age and vaccination status.
mRNA-1273 shows greater COVID-19 protection than NVX-CoV2705 in retrospective US cohort study
New Data Shows One Vaccine Type Works Better
A retrospective matched cohort study of 103,710 US insured adults found mRNA-1273 vaccination was associated with lower rates of medically-a…
In a head-to-head comparison, the mRNA COVID-19 vaccine was more effective at preventing severe outcomes than the protein-based vaccine duri…
Autoantibodies neutralizing type I interferons linked to severe COVID-19 pneumonia in myasthenia gravis patients
A Hidden Immune Flaw Makes COVID Far More Dangerous for Some Patients
An international cohort study of 85 unvaccinated, untreated SARS-CoV-2-infected MG patients found that those with autoantibodies neutralizin…
Doctors have discovered why some people with a common nerve disease face a terrifying risk from COVID-19, pointing to a simple way to keep t…
Household SARS-CoV-2 exposure linked to transmission in Turkish families with children.
Kids at Home: How Simple Habits Stop Virus Spread
This ambispective community-based observational cohort study examined 119 households in Zonguldak, Türkiye, comprising 501 individuals, all …
Keeping masks on and separating sick family members is the best way to protect kids and adults alike.
Prolonged prone positioning shows oxygenation benefit but inconclusive mortality effect in COVID-19 ARDS
Longer prone positioning may improve oxygen levels in COVID-19 ARDS patients
A meta-analysis of 996 COVID-19 patients with moderate-to-severe ARDS compared prolonged (>24 h/session) to standard (≤24 h/session) prone p…
Prolonged prone positioning for severe lung failure showed a trend toward lower death rates but increased pressure injury risks in COVID-19 …
Extended prone positioning associated with lower mortality but more pressure injuries in COVID-19 ARDS
Could longer time spent face-down help more COVID-19 patients on ventilators survive?
A meta-analysis of 2412 adults with moderate-to-severe COVID-19 ARDS found extended prone positioning (≥24 h) was associated with reduced mo…
Keeping COVID-19 patients face-down longer than 24 hours lowers death risk but increases pressure sores, with no change to ventilator time.
COVID-19 mRNA vaccines show sustained effectiveness against hospitalization in U.S. veterans
Did COVID-19 vaccines keep protecting veterans from hospitalization?
An observational study of U.S. veterans at five VA Medical Centers found COVID-19 mRNA vaccine effectiveness against hospitalization remaine…
COVID-19 mRNA vaccines kept protecting veterans from hospitalization even as the Delta variant surged in the summer of 2021.
Observational study finds COVID-19 mRNA vaccines effective against infection in frontline workers, with reduced protection during Delta spread.
Did COVID vaccines work against infection? Yes, but less so against Delta.
An observational study of frontline workers in eight U.S. locations found COVID-19 mRNA vaccines were effective against SARS-CoV-2 infection…
COVID-19 mRNA vaccines prevent infection in frontline workers, but protection drops as the contagious Delta variant spreads.
Case series describes first 100 COVID-19 patients in Zambia and national response efforts.
What happened to Zambia's first 100 COVID-19 patients?
A case series provides an overview of the first 100 individuals diagnosed with COVID-19 in Zambia and the subsequent national mitigation and…
Zambia's first 100 COVID-19 patients sparked immediate mitigation efforts as health authorities documented the virus's early arrival on the …
Observational report describes COVID-19 prevention strategy at four overnight camps in Maine
How did summer camps keep COVID-19 from spreading in 2020?
An observational report describes a COVID-19 prevention and mitigation strategy implemented for attendees and staff at four overnight camps …
Four Maine camps shared their 2020 summer safety plans to stop COVID-19 spread, though the report describes the strategies without sharing f…
HIV outbreak reported among persons who inject drugs in Kanawha County, West Virginia
HIV outbreak reported among people who inject drugs in West Virginia county
A descriptive outbreak investigation report documented an HIV outbreak among persons who inject drugs in Kanawha County, West Virginia, duri…
Health officials report an HIV outbreak among people who inject drugs in Kanawha County, West Virginia, during the pandemic.