Observational study identifies sensory perception differences in schizophrenia and first-episode psychosis
Simple tests reveal unique sensory signs for early psychosis types
This observational study investigated psychophysical differences in pictorial size perception and auditory discomfort among patients with sc…
New low-cost tests can spot unique sensory changes that help doctors tell schizophrenia apart from bipolar disorder in early psychosis cases…
Meta-analysis on psychological interventions and early psychosis care for depression and psychosis
Psychological interventions cut major depression risk by 43% after treatment
This meta-analysis synthesizes evidence on psychological interventions for subclinical depression and early intervention for first-episode p…
Early psychological help for subclinical symptoms lowers major depression risk by 43% after treatment and 33% a year later, a meta-analysis …
Criminal legal involvement correlates with baseline symptoms and substance use in US first-episode psychosis patients.
Early psychosis care may lower the risk of arrest
This secondary analysis of a cluster randomized controlled trial examined criminal legal involvement (CLI) in 381 US patients with first-epi…
When psychosis is caught and treated sooner, people are less likely to end up tangled in the legal system during recovery.
Systematic review finds immune markers IL-1β and TNF-α associated with negative symptoms in first episode psychosis
Inflammation Linked to Low Energy in Early Psychosis
A systematic review of 7 case-control studies found individuals with first episode psychosis generally showed elevated peripheral blood immu…
High levels of inflammatory markers in the blood are linked to the low energy and lack of motivation seen in people with early psychosis.
Extended early intervention service improves functioning in first-episode psychosis versus standard care
Extending early intervention services may improve functioning for some young people with first-episode psychosis.
A randomized controlled trial of 400 individuals with first-episode psychosis found that extending early intervention service (EIS) for one …
Extending early intervention care for young people with first-episode psychosis leads to higher employment rates and better social functioni…
Corticolimbic Glutamate-Functional Connectivity Associations Found in Antipsychotic-Naive CHR-P Individuals
Could early brain changes in psychosis risk be linked to specific chemical connections?
An observational study of antipsychotic-naive clinical high-risk for psychosis (CHR-P) participants (n=22), healthy controls (n=23), and fir…
People at high risk for psychosis show weaker brain chemical connections before symptoms appear, unlike those who have already developed the…
12-year follow-up of extended early intervention for first-episode psychosis in Hong Kong
Long-term study tracks recovery rates for people with first psychosis episode
A 12-year follow-up of an RCT in Hong Kong compared a 1-year extension of early intervention (3-year EI) to 1-year step-down care (2-year EI…
Twelve years after a first psychosis episode, only 25% of patients regained daily functioning, though extra early care helped control sympto…