Radiomics features on MRI discriminate sellar LCH from tumor marker-negative GCTs with an AUC of 0.81
AI Scan Helps Doctors Spot Confusing Brain Tumors
This retrospective cohort study evaluated 93 patients with sellar region tumors to discriminate between Langerhans cell histiocytosis (LCH) …
A new computer system helps doctors tell two similar brain tumors apart using MRI scans.
Nivolumab plus ipilimumab versus nivolumab in advanced neuroendocrine carcinoma phase II trial
New Combo Shows Modest Promise for Hard-to-Treat Neuroendocrine Cancers
This randomized phase II trial enrolled 185 patients with advanced neuroendocrine carcinoma refractory to platinum-based chemotherapy.
For patients with rare, aggressive neuroendocrine cancers that resist initial treatment, this study offers a new, though modest, combination…
Narrative review offers practical recommendations for implementing PET-guided therapy workflows in clinical practice
PET scans now guide your radiation treatment
This narrative review synthesizes evidence regarding the implementation of PET-guided therapy workflows.
Imagine standing in a doctor's office waiting for radiation therapy.
Meta-analysis identifies germline susceptibility loci for rare cancers including MDS and GIST
Genes linked to rare cancers found in large study of over 480,000 people
This meta-analysis of observational cohorts from over 480,000 individuals identified novel germline susceptibility loci for rare cancers.
A huge study of over 480,000 people found new genes that raise the risk of several rare cancers, offering clues for families and doctors.
Review examines multi-omics approaches to enhance diagnostic precision and treatment decisions in pediatric neuroblastoma
The AI Tool That's Changing How Doctors Fight Childhood Cancer
This narrative review evaluates the application of multi-omics approaches, including transcriptomics and radiomics, for children with neurob…
A new AI tool combines genetic tests and imaging to help doctors diagnose and treat unpredictable childhood cancer called neuroblastoma more…
Phase II RCT finds no benefit for adding capecitabine to 177Lu-Dotatate in advanced NETs
Adding a Drug Actually Hurted These Patients
A Phase II randomized controlled trial in 111 patients with advanced somatostatin receptor-positive GEP or bronchopulmonary NETs compared…
Adding a common chemotherapy drug to cancer treatment actually made tumors grow faster and reduced survival time for these patients.
Surgical excision for neonatal teratoma and cryptorchid testis showed high maturity rates and no recurrences in 10 cases
A Rare Newborn Tumor Doctors Almost Missed
This case report and literature review evaluated 10 cases of neonatal mature teratoma, intra-abdominal cryptorchid testis, or testicular tor…
A routine prenatal ultrasound found a rare newborn tumor twisting inside a baby's belly before birth, leading to quick surgery and a full re…
Pheochromocytoma misdiagnosed as allergic vasculitis in a 36-year-old male led to ulcer healing but required toe amputation
24 Years of Leg Ulcers Led Back to a Hidden Tumor
This case report describes a 36-year-old male with pheochromocytoma initially misdiagnosed as allergic vasculitis.
A man's 24-year leg ulcer mystery ended when a hidden adrenal tumor was found, proving the wrong diagnosis kept his wounds from healing.
PD-L1 expression shows subtype-specific prognostic value in skin neoplasms, meta-analysis finds
Does a common cancer marker predict survival in skin cancers? It depends
A meta-analysis of 24 observational studies found PD-L1 expression was not significantly associated with overall survival (HR=0.89, 95% CI: …
A common skin cancer marker doesn't predict survival for everyone, but it does for specific types like Merkel cell carcinoma and melanoma.
Endoscopic plasma resection shows excellent outcome in single pediatric tongue root schwannoma case
Single case report describes successful removal of rare tongue tumor in teen
A case report with literature review describes a 17-year-old male with tongue root schwannoma treated via endoscopic-assisted low-temperatur…
Doctors removed a rare tongue tumor from a 17-year-old boy through his mouth using a specialized technique that caused no external cuts or c…
FDA Approves Zynyz (retifanlimab-dlwr) for Metastatic Anal Canal Cancer and Merkel Cell Carcinoma
FDA approves new drug Zynyz for two rare and aggressive types of cancer
The FDA has approved Zynyz, a PD-1 blocking antibody, for two indications: first-line treatment of inoperable locally recurrent or metastati…
FDA approves new drug Zynyz to treat two rare and aggressive cancers: advanced anal cancer and Merkel cell carcinoma.
Higher TFF1 Expression Linked to Lower Bilateral Retinoblastoma Risk
Could a simple test help identify retinoblastoma risk in children?
In a meta-analysis of 521 retinoblastoma patients, higher TFF1 expression was linked to reduced bilateral involvement (RR=0.57, p=0.0041) an…
A new test for a protein called TFF1 could help doctors spot retinoblastoma risk in children and predict if the cancer will affect both eyes…
Research across Cancer
Related studies from across the Cancer family.
