Biochemical marker decline may not indicate clinical stability in intracranial growing teratoma syndrome
Tumor Markers Drop But Mass Grows: A Case Report
This case report describes two pediatric patients with suprasellar mixed germ cell tumors who experienced biochemical success despite radiol…
In two children with brain germ cell tumors, tumor markers fell sharply while the tumor itself enlarged, a rare condition called growing ter…
Radiomics and deep learning provide promising tools for precise assessment of adrenal masses
AI and radiomics show promise for adrenal tumor diagnosis
This systematic review evaluates the utility of radiomics and deep learning (DL) techniques in assessing adrenal masses including pheochromo…
A new review finds AI-powered imaging analysis could improve how doctors diagnose adrenal masses, but clinical use is still far off.
SDHD Variant Carriers Face High Penetrance and Multifocal Tumors
SDHD Genetic Variants Linked to Increasing Risk of Tumors Over Time
A meta-analysis of SDHD pathogenic variant carriers reveals age-specific penetrance rising to 82% by age 60, with 75% developing multifocal …
New data shows that the risk of developing tumors increases significantly with age for people carrying specific SDHD genetic variants.
Laryngeal obstruction as initial sign of MEN2B in two pediatric cases with RET mutations
Rare genetic disorder first shows as breathing trouble in children
This case report describes 2 pediatric patients with MEN2B presenting with laryngeal obstruction and progressive respiratory compromise as i…
Two children with a rare genetic condition first showed breathing trouble from nerve growths in the airway, not the usual symptoms.
Concurrent primary aldosteronism and micro-pheochromocytoma can coexist in patients with paroxysmal hypertension
Surgery helps woman with complex high blood pressure and tumors
This case report describes a 65-year-old woman with paroxysmal hypertension who presented with concurrent primary aldosteronism and a micro-…
A 65-year-old woman found to have two different types of adrenal gland issues was successfully treated after surgery.
Phase II pilot study of hu14.18K322A plus chemotherapy in 153 children with high-risk neuroblastoma
New Antibody Boosts Survival in High-Risk Neuroblastoma
This Phase II pilot study enrolled 153 previously untreated children with high-risk neuroblastoma. The study assessed hu14.18K322A combined …
This study shows that combining a new antibody with standard chemotherapy may improve survival rates for children with high-risk neuroblasto…
Case report and literature review describes imaging features of fetal oral cavity immature teratoma
Fetal Oral Tumor Imaging Reveals Rare Teratoma Clues
This case report and literature review describes a fetus with an immature teratoma in the oral cavity. The authors synthesize multimodal ima…
A rare tumor in a baby’s mouth shows clear imaging signs that help doctors tell it apart from other growths.
Systematic review and meta-analysis of intra-arterial chemotherapy for pediatric retinoblastoma outcomes
Meta-analysis links intra-arterial chemotherapy to better outcomes for pediatric retinoblastoma
This systematic review and meta-analysis evaluated intra-arterial chemotherapy (IAC) versus intravenous chemotherapy (IVC) for pediatric ret…
A meta-analysis of twelve studies suggests intra-arterial chemotherapy improves survival and eye salvage compared to intravenous chemotherap…
Radiomics features on MRI discriminate sellar LCH from tumor marker-negative GCTs with an AUC of 0.81
AI Scan Helps Doctors Spot Confusing Brain Tumors
This retrospective cohort study evaluated 93 patients with sellar region tumors to discriminate between Langerhans cell histiocytosis (LCH) …
A new computer system helps doctors tell two similar brain tumors apart using MRI scans.
Nivolumab plus ipilimumab versus nivolumab in advanced neuroendocrine carcinoma phase II trial
New Combo Shows Modest Promise for Hard-to-Treat Neuroendocrine Cancers
This randomized phase II trial enrolled 185 patients with advanced neuroendocrine carcinoma refractory to platinum-based chemotherapy.
For patients with rare, aggressive neuroendocrine cancers that resist initial treatment, this study offers a new, though modest, combination…
Narrative review offers practical recommendations for implementing PET-guided therapy workflows in clinical practice
PET scans now guide your radiation treatment
This narrative review synthesizes evidence regarding the implementation of PET-guided therapy workflows.
Imagine standing in a doctor's office waiting for radiation therapy.
Meta-analysis identifies germline susceptibility loci for rare cancers including MDS and GIST
Genes linked to rare cancers found in large study of over 480,000 people
This meta-analysis of observational cohorts from over 480,000 individuals identified novel germline susceptibility loci for rare cancers.
A huge study of over 480,000 people found new genes that raise the risk of several rare cancers, offering clues for families and doctors.
Research across Cancer
Related studies from across the Cancer family.
