National trends show rising Hepatitis C and opioid use disorder rates in pregnant women at delivery
Study finds rising Hepatitis C and opioid disorder rates among pregnant women in the U.S
An observational study of pregnant women at delivery hospitalization in the United States from 2000-2015 found significant increases in both…
Hepatitis C and opioid use disorder rates rose significantly among U.S. pregnant women delivering in hospitals between 2000 and 2015.
Updated PHS guidelines recommend HIV, HBV, and HCV testing for pediatric transplant candidates under 12
U.S. updates guidelines for HIV and hepatitis testing in young transplant candidates
Updated U.S. Public Health Service guidelines recommend testing for HIV, Hepatitis B, and Hepatitis C in transplant candidates under age 12.
U.S. doctors now must test children under 12 for HIV and hepatitis before organ transplants to protect both the patient and the donated orga…
Hepatitis C treatment patterns examined in insured US adults
Study examines hepatitis C treatment patterns among insured U.S. adults
An observational study examined hepatitis C treatment patterns among insured adults in the United States.
Hepatitis C treatment patterns for insured adults in the United States are now described, yet success rates and side effects remain unreport…
Updated guidance for hepatitis C virus exposure and acute infection in healthcare personnel
Updated guidance for hepatitis C testing and treatment after healthcare exposures
This guidance document provides updated recommendations for laboratory testing, follow-up, and treatment of acute hepatitis C virus infectio…
Health authorities released new steps for doctors and nurses to follow after potential hepatitis C exposure from infected blood or fluids.
Hepatitis C cases increasing dramatically in US population, especially among younger adults
Why are hepatitis C cases rising dramatically, especially among younger adults?
A report on hepatitis C epidemiology in the United States indicates cases are increasing dramatically, with particularly notable increases a…
A new report shows hepatitis C cases are rising dramatically in the United States, especially among younger adults.
CDC issues hepatitis C testing recommendations for perinatally exposed infants and children
CDC updates hepatitis C testing guidelines for infants and children exposed at birth
The CDC has published recommendations for hepatitis C testing in perinatally exposed infants and children in the United States.
CDC updated hepatitis C testing rules for babies born to infected mothers to help doctors catch infections early.
8-week glecaprevir/pibrentasvir shows 96.2% SVR12 in acute HCV treatment-naïve adults
Can a short treatment course cure most cases of acute hepatitis C?
A single-arm Phase IIIb study of 286 treatment-naïve adults with acute HCV found 96.2% achieved SVR12 with an 8-week glecaprevir/pibrentasvi…
A short eight-week treatment cured 96.2% of adults with new hepatitis C infections, with a perfect success rate for those who completed the …
HCV treatment with direct-acting antivirals linked to reduced alcohol use in people who inject drugs
HCV treatment linked to reduced alcohol use in people who inject drugs
A secondary analysis of a pragmatic RCT in 755 people who inject drugs (PWID) found that achieving sustained virological response (SVR) was …
People who inject drugs and cured of hepatitis C showed lower alcohol use scores at every follow-up visit compared to their baseline.
Research across Hepatitis
Related studies from across the Hepatitis family.
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
Epigallocatechin-3-gallate shows positive therapeutic effects on various digestive system diseases in animal models
Green tea compound shows potential for several digestive diseases
This meta-analysis of 63 preclinical studies involving 738 animals indicates that Epigallocatechin-3-gallate (EGCG) has a positive therapeut…
A review of animal studies suggests a green tea compound could help treat various cancers and digestive conditions.
PEG-IFN plus novel agents may boost functional cure in chronic hepatitis B
Combination therapies may improve functional cure rates for chronic hepatitis B
This narrative review examines combining pegylated interferon-α with novel immunotherapies (antigen-reduction strategies, therapeutic vaccin…
A review suggests combining pegylated interferon with new immunotherapies could help achieve functional cure in chronic hepatitis B patients…
HLA-B*57:01-guided abacavir prescribing is the clearest preventive paradigm from HLA associations
HLA genes shape HIV and hepatitis vaccine responses and drug reactions
This narrative review examines HLA polymorphisms in HIV, hepatitis C, and hepatitis B. The clearest preventive paradigm is HLA-B*57:01-guide…
A review finds that HLA genes strongly influence how people respond to HIV and hepatitis vaccines and how they react to certain medications.
One in six blood donors in Cameroon carries Plasmodium infection, meta-analysis finds
1 in 6 blood donors in Cameroon carries malaria parasite
A systematic review and meta-analysis of 18 studies (~12,500 donations) found a 16.6% pooled prevalence of Plasmodium spp. in Cameroonian bl…
A review of 18 studies finds 16.6% of blood donations in Cameroon contain Plasmodium, the malaria parasite.
Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
New antiviral strategies show promise for chronic hepatitis B infection
This narrative review synthesizes evidence on antiviral and immunotherapeutic strategies for chronic hepatitis B. The authors highlight func…
A review of new treatments suggests combination therapies may offer future value for managing chronic hepatitis B, cirrhosis, and liver canc…
Meta-analysis identifies genetic variants linked to HBV susceptibility and HCC risk
Genetic Keys Unlock Why Some Get Liver Cancer From Hepatitis B
This meta-analysis of East Asian cohorts examined genetic variants associated with hepatitis B virus infection and hepatocellular carcinoma …
New research shows specific gene changes help explain why some people get Hepatitis B while others stay healthy.
Systematic review and meta-analysis of biopsy-guided versus clinically guided withdrawal in autoimmune hepatitis
Biopsy-guided withdrawal shows no benefit over clinical guidance for autoimmune hepatitis
This systematic review and meta-analysis evaluated relapse rates after treatment withdrawal in patients with autoimmune hepatitis.
A meta-analysis of 518 patients found that biopsy-guided withdrawal did not lower relapse rates compared to clinically guided withdrawal in …
HEV 239 vaccine induces durable humoral and cellular immunity in Bangladeshi women
Hepatitis E vaccine shows durable immunity in women
This longitudinal cohort study in 1480 women aged 16-39 years in Bangladesh found that HEV 239 (Hecolin) vaccination led to significantly hi…
A hepatitis E vaccine kept women protected for up to 3 years, with stronger immune memory than a comparison group.
Pegylated interferon alpha associated with HBsAg clearance in postpartum women with chronic HBV infection
New treatment clears hepatitis B in 3 out of 10 women after childbirth
This prospective cohort study evaluated 263 postpartum women with chronic hepatitis B virus infection and baseline HBsAg levels ≤3000 IU/mL.
A new treatment clears hepatitis B markers in nearly 30% of women after childbirth, offering fresh hope for a functional cure during a uniqu…
Hepatic steatosis prevalence and impact in autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis
Fatty liver makes autoimmune hepatitis and PBC worse, but not PSC
This systematic review and meta-analysis of 19,898 patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing c…
A large review found fatty liver is common in autoimmune liver diseases and makes outcomes worse for some patients, but not others.
Absence of antiviral therapy and multiple chemotherapeutic agents increase HBV reactivation risk after TACE
No Antiviral Meds Raise Liver Cancer Risks After Chemo
This retrospective cohort study of 168 HBsAg-positive HCC patients undergoing TACE found that absence of prophylactic antiviral therapy (OR …
Many liver cancer patients with hepatitis B face avoidable risks during chemo—because they’re not getting a simple antiviral pill most alrea…
Questions about Hepatitis C
How should healthcare workers follow up after an acute Hepatitis C Virus infection?
Healthcare workers with acute HCV should undergo baseline and serial HCV RNA testing, with follow-up for at least 6 months to confirm clearance or initiate treatment.
Full answer →Why is the CDC recommending universal screening for Hepatitis C for pregnant women?
The CDC recommends universal Hepatitis C screening for all pregnant women because infection rates have doubled in the US since 2009, many cases go undiagnosed, and screening is now considered cost-effective.
Full answer →Does taking ribavirin for Hepatitis C cause more genetic mutations in the virus?
Yes, ribavirin increases genetic mutations in HCV, as shown by a randomized trial that found higher mutational load and specific nucleotide changes in the virus.
Full answer →How has the rate of Hepatitis C changed among younger adults in the US?
Hepatitis C rates have increased dramatically among younger US adults, driven by the opioid epidemic and injection drug use.
Full answer →