Hepatic steatosis prevalence and impact in autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis
Fatty liver makes autoimmune hepatitis and PBC worse, but not PSC
This systematic review and meta-analysis of 19,898 patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing c…
A large review found fatty liver is common in autoimmune liver diseases and makes outcomes worse for some patients, but not others.
Absence of antiviral therapy and multiple chemotherapeutic agents increase HBV reactivation risk after TACE
No Antiviral Meds Raise Liver Cancer Risks After Chemo
This retrospective cohort study of 168 HBsAg-positive HCC patients undergoing TACE found that absence of prophylactic antiviral therapy (OR …
Many liver cancer patients with hepatitis B face avoidable risks during chemo—because they’re not getting a simple antiviral pill most alrea…
Narrative review on ICIs in patients with viral infections and solid tumors
Cancer Immunotherapy Works Differently in Viral Infections
This narrative review synthesizes evidence on immune checkpoint inhibitors in patients with viral infections and solid tumors.
Cancer immunotherapy can still work—and sometimes even control viruses like hepatitis or HIV—but doctors must watch for dangerous flare-ups.
HBV-positive status linked to higher surgical conversion in unresectable HCC receiving triple therapy
HBV-positive linked to better outcomes in liver cancer triple therapy
This single-center retrospective cohort study evaluated triple therapy with TACE, lenvatinib, and PD-1 inhibitors in 190 patients with initi…
In unresectable liver cancer, triple therapy with TACE, lenvatinib, and PD-1 inhibitors worked better in HBV-positive patients, a small retr…
Integrative review of Epimedium flavonoids in hepatitis and cirrhosis shows preclinical promise but lacks clinical validation
Ancient Herb Shows New Promise for Liver Scarring and Hepatitis
This integrative review synthesizes data from 33 high-impact studies regarding Epimedium species and its bioactive flavonoids, icariin and i…
This research suggests a traditional herb may offer a new way to protect the liver, but more work is needed to prove it’s safe and effective…
Meta-analysis of 55 studies assesses HCV prevalence trends across Eastern Mediterranean Region populations
HCV Rates Drop in High-Risk Groups After 2015
This umbrella review synthesizes data from 55 meta-analyses evaluating hepatitis C virus (HCV) prevalence in the Eastern Mediterranean Regio…
Imagine walking into a doctor's office and feeling a knot of worry in your stomach.
Randomized trial shows ribavirin increases mutational load and specific transition signatures in HCV
Ribavirin linked to increased hepatitis C virus mutations in trial
This secondary analysis of a randomized trial in HCV-infected participants found ribavirin exposure significantly increased total mutational…
Ribavirin treatment linked to increased hepatitis C virus mutations in a trial, though real-world impact on cure rates remains unclear.
Narrative review synthesizes evidence on NAFLD, NASH, and viral hepatitis management without reported trial data
Your Liver Has an Immune Army — and It Can Turn Against You
This narrative review addresses management considerations for nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH),…
Your liver's own immune cells can turn on itself to cause permanent scarring, but scientists are now mapping these cells to stop the damage …
Review of liver disease immunomodulation strategies notes precision over broad suppression
Your Liver's Immune Cells Play Both Hero and Villain at Once
This narrative review examines immunomodulation approaches for liver diseases, including acute liver injury, HBV infection, MASLD/MASH, fibr…
Liver immune cells can both damage and repair your organ at the same time, a discovery that could unlock new precision treatments for hepati…
Infliximab in IVIG-resistant Kawasaki disease with cholestatic hepatitis: case report
Can a new drug stop heart damage in Kawasaki disease when standard treatments fail?
A case report describes a 2-year-old Han Chinese male with IVIG-resistant Kawasaki disease and cholestatic hepatitis treated with infliximab…
In a two-year-old boy with Kawasaki disease, the drug infliximab quickly stopped his fever and liver trouble, yet his heart artery damage ke…
Meta-analysis of 9 studies estimates HCV seroprevalence of 3.63% among African refugees and displaced persons
Hidden Virus Threats Among Displaced People
This systematic review and random-effects meta-analysis of 9 studies estimated hepatitis C virus (HCV) seroprevalence among refugees, asylum…
A new look at data shows hepatitis C is very common among refugees and displaced people in Africa, where they often face huge barriers to ge…
Meta-analysis finds high prevalence of zoonotic diseases in African pastoralist livestock systems
Three Deadly Animal-Linked Diseases Hiding in Plain Sight Across Africa
A systematic review and meta-analysis of 34 studies in African pastoralist systems found high prevalence rates for Rift Valley fever and Cri…
Three deadly livestock diseases hide in African pastoral communities, where women face the highest risk despite official counts suggesting t…
Questions about Hepatitis
Is there an increase in pediatric hepatitis of unknown cause in the US?
Recent reports indicate there was no increase in pediatric hepatitis of unknown cause or adenovirus trends in US children compared to pre-pandemic levels.
Full answer →What causes severe hepatitis in children with adenovirus infection in Alabama?
Severe hepatitis in children with adenovirus in Alabama is linked to specific enteric serotypes like 41, which cause intense liver inflammation and immune reactions, though the virus's exact role as the sole cause remains unclear.
Full answer →Has the US analysis found a common cause for acute hepatitis in kids?
US analysis has not found a single common cause for acute hepatitis in children, though some cases are linked to adenovirus while others remain unknown.
Full answer →Do adenovirus stool testing results show higher levels than pre-pandemic times?
No, adenovirus stool testing results have not shown higher levels than pre-pandemic times, according to US surveillance data.
Full answer →Is there an increase in pediatric hepatitis of unknown cause in the US?
No, US surveillance data through 2022 found no increase in pediatric hepatitis of unknown cause or adenovirus trends compared to pre-pandemic levels.
Full answer →Can adenovirus infection cause severe hepatitis in children?
Adenovirus infection has been found in children with severe acute hepatitis, but its exact role as the cause is still unclear to doctors.
Full answer →