HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Oncology
Meta-analysis
Minimally invasive surgical thermal ablation shows improved technical success and safety in liver malignancy patients.
Minimally invasive surgery offers safe, effective treatment for liver cancer tumors
This systematic review and meta-analysis evaluated 3983 patients with hepatocellular carcinoma or colorectal liver metastases treated with m…
Minimally invasive surgery safely destroys liver cancer tumors with just 1% failure rate and 0.25% death risk for patients who can't have fu…
Apr 14, 2026
Gastroenterology
Phase II
Regorafenib plus nivolumab in second-line hepatocellular carcinoma showed safety and survival signals in a Phase IIa trial.
Some Liver Cancer Patients Are Surviving Far Longer on a New Drug Combination
This Phase IIa trial evaluated regorafenib plus nivolumab as an add-on therapy in patients with hepatocellular carcinoma who had progressed …
A combination of regorafenib and nivolumab showed unexpectedly long survival in people with advanced liver cancer who had already exhausted …
Apr 14, 2026
Oncology
Cohort
Cell cycle pathway alterations linked to worse survival and recurrence after liver transplant for HCC
New Liver Test Uses DNA to Predict Survival
A prospective single-center cohort study of 91 patients with hepatocellular carcinoma (HCC) after liver transplant found that cell cycle pat…
A new liver test analyzes tumor DNA to predict survival, revealing that even small cancers can be dangerous if they carry specific genetic c…
Frontiers
Apr 14, 2026
Allergy & Immunology
Cohort
High TRIM25 expression associates with shorter survival in hepatocellular carcinoma patients.
Why a Hidden Liver-Cancer Switch Helps Tumor Cells Resist Their Own Death
This cohort study analyzed TRIM25 expression levels in patients with hepatocellular carcinoma (HCC) using TCGA, ICGC, and paired tissue samp…
A single protein helps liver cancer cells block their body's natural self-destruct mode, and removing it could open new treatment doors.
Frontiers
Apr 13, 2026
Gastroenterology
Phase II
SBRT plus PD-1 inhibitor and lenvatinib improved PFS in oligoprogressive HCC patients.
Radiation Plus Immune Drugs Stops Liver Cancer Growth
This prospective Phase 2 study evaluated stereotactic body radiation therapy (SBRT) combined with continued first-line PD-1 inhibitor-based …
Combining targeted radiation with ongoing immune therapy can restart cancer control in patients whose disease was slowly spreading again.
Apr 12, 2026
Oncology
Cohort
NSI-driven quality program linked to faster ambulation after liver resection for HCC
A Simple Hospital Checklist Is Helping Liver Cancer Patients Heal Faster
A cohort study of 172 patients undergoing curative liver resection for hepatocellular carcinoma compared a structured Nursing-Sensitive Indi…
Better teamwork and simple checklists after surgery are leading to safer, faster recoveries for liver cancer patients.
Frontiers
Apr 11, 2026
Oncology
Meta-analysis
Meta-analysis finds immunotherapy efficacy in HCC varies by aetiology, strongest in HBV-related disease
1. HEADLINE
A systematic review and meta-analysis of 26 studies in hepatocellular carcinoma found immune checkpoint inhibitor efficacy varies by aetiolo…
For the first time, a major analysis confirms that *why* you have liver cancer is a powerful clue to *if* a leading treatment will help you …
Apr 10, 2026
Rheumatology
Guideline
Guideline reviews perioperative immunotherapy for hepatocellular carcinoma after resection or ablation
A New Strategy Emerges to Stop Liver Cancer From Coming Back
A guideline reviews perioperative immunotherapy for hepatocellular carcinoma after resection or ablation. Adjuvant atezolizumab plus bevaciz…
Doctors are finding smarter ways to use the body’s own immune system around the time of surgery to give patients with liver cancer a better …
Frontiers
Apr 10, 2026
Oncology
Meta-analysis
Adjuvant immune checkpoint inhibitors after curative HCC treatment associated with reduced recurrence risk
Adjuvant Immune Checkpoint Inhibitors May Reduce Liver Cancer Recurrence Risk
A meta-analysis of 3,478 patients with curatively treated hepatocellular carcinoma found adjuvant immune checkpoint inhibitor-based treatmen…
Adding immune checkpoint inhibitors after surgery or ablation significantly lowers the risk of liver cancer returning, giving patients a str…
Apr 9, 2026
Oncology
Cohort
Radiotherapy associated with improved response and survival in HCC patients receiving immune-targeted therapy
Does adding radiation help some liver cancer patients respond better to their immune therapy?
A multicenter retrospective study of 238 HCC patients receiving immune-targeted therapy found radiotherapy was associated with higher object…
Adding radiation to immune therapy helped more advanced liver cancer patients see their tumors shrink and live longer compared to those who …
Frontiers
Apr 9, 2026
Oncology
Cohort
Multiphasic CT-based deep learning model predicts early HCC recurrence after liver transplantation
New AI model shows promise for predicting early liver cancer recurrence after transplant
This retrospective cohort study evaluated a multiphasic CT-based multimodal deep learning (MD DL) model in 147 liver transplant recipients. …
A new AI tool using CT scans and lab data predicts early liver cancer return after transplant with high accuracy in past patient records.
Frontiers
Apr 6, 2026
Gastroenterology
SBRT as bridging therapy in advanced cirrhosis HCC patients shows 67% transplant eligibility at 1 year
Small study explores radiation therapy for liver cancer patients awaiting transplant
A prospective pilot trial in 9 HCC patients with Child-Pugh B8 or worse cirrhosis found that SBRT (40 Gy/5 fractions) as a bridging strategy…
A small study found that focused radiation therapy helped 67% of liver cancer patients with advanced scarring stay eligible for a transplant…
Apr 3, 2026