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Oncology
Meta-analysis
Meta-analysis finds no link between psychosocial factors and most cancer risks
Study links some psychosocial factors to higher lung cancer risk in large data review
This individual-participant data meta-analysis of 22 cohorts (N=421,799) found no association between psychosocial factors and overall cance…
Low social support, being single, or experiencing a loss are linked to higher lung cancer risk, but lifestyle factors like smoking may expla…
Apr 9, 2026
Oncology
Meta-analysis
Elevated neutrophil-to-lymphocyte ratio predicts brain metastasis risk in lung cancer patients.
Could a simple blood test help find who is most at risk for brain metastasis from lung cancer?
This systematic review and meta-analysis evaluated three immune inflammatory markers in 3,643 participants with lung cancer. Elevated neutro…
A simple blood test showing high inflammation markers can predict who is most likely to develop brain metastasis from lung cancer.
Frontiers
Apr 9, 2026
Oncology
Cohort
Hospitalized malignant neoplasm patients show high comorbidity burden and distinct disease patterns across 163 Chinese hospitals.
Hospitalized cancer patients in China often have other serious health conditions
This retrospective cohort study examined 107,029 hospitalized patients with malignant neoplasms across 163 hospitals in Zhanjiang, China. Th…
Hospitalized cancer patients in China often face five other serious health conditions, with rural residents, men, and those aged 65 or older…
Frontiers
Apr 9, 2026
Allergy & Immunology
Cohort
Federated model adaptation improves radiation pneumonitis prediction in lung cancer patients receiving immunotherapy.
Can we predict lung inflammation risk in patients getting immunotherapy?
This cohort study evaluated a federated radiomics model for predicting radiation pneumonitis in 610 lung cancer patients treated with defini…
A new model adapts to predict lung swelling risks for cancer patients receiving both radiation and immunotherapy, fixing errors in older too…
Frontiers
Apr 9, 2026
Pulmonology & Critical Care
RCT
Nonintubated anesthesia lowers postoperative NLR in thoracoscopic lung cancer resection compared to traditional intubation.
Nonintubated anesthesia may lower inflammation markers after lung cancer surgery in a small study.
This randomized controlled trial enrolled 58 patients undergoing video-assisted thoracoscopic lung surgery to compare nonintubated anesthesi…
Patients without breathing tubes during lung cancer surgery showed significantly lower inflammation levels 24 hours after the operation comp…
Apr 6, 2026
Pulmonology & Critical Care
Meta-analysis
Meta-analysis compares three lung fiducial marker insertion approaches for stereotactic body radiotherapy
Study compares three ways to place lung markers for radiation therapy
A systematic review and meta-analysis of 27 studies involving 2,065 patients compared transthoracic, endovascular, and endobronchial approac…
For lung radiation markers, going through the windpipe is most accurate and causes fewer lung air leaks than other methods.
Apr 5, 2026
Psychiatry
RCT
Home-based pulmonary rehabilitation reduces anxiety and depression in advanced lung cancer patients
Home-based exercise program with nurse support may help reduce anxiety and depression in advanced lung cancer patients
In a randomized controlled trial of 104 patients with stage III-IV lung cancer, a nurse-supported hybrid home-based pulmonary rehabilitation…
A home exercise program with nurse support reduced anxiety and depression while keeping daily activities stable for advanced lung cancer pat…
Apr 5, 2026
Oncology
RCT
Computational framework reconstructs multidimensional clinical profiles from published Kaplan-Meier images
Can a computer reconstruct hidden patient stories from old cancer trial charts?
Methodological research using simulated data and empirical cancer cohorts (n=228 lung, n=929 colon) evaluated the MD-JoPiGo framework. The t…
A new tool reconstructs hidden patient stories from old cancer trial charts, revealing how age and tumor markers interacted using only stand…
medRxiv
Apr 4, 2026
Radiology & Imaging
Cohort
Chest radiograph-derived age acceleration shows modest association with lung cancer incidence in PLCO cohort
Can a chest X-ray show how fast your lungs are aging?
A retrospective cohort analysis of 23,213 PLCO trial participants found that higher chest radiograph-derived age acceleration was independen…
A routine chest X-ray can reveal if your lungs are aging faster than expected, a sign linked to a higher risk of developing lung cancer late…
medRxiv
Apr 3, 2026
Oncology
Cohort
COVID-19 associated with increased lung cancer risk in current smokers; spike protein drives tumorigenesis in mice
Study finds link between COVID-19 and higher lung cancer risk in current smokers
A retrospective cohort analysis of 166,807 current smokers found COVID-19 was associated with increased lung cancer risk (RR 1.22; HR 1.50).…
Current smokers with a history of COVID-19 face a higher risk of developing lung cancer, a link scientists traced to a specific virus protei…
Frontiers
Apr 2, 2026
Pulmonology & Critical Care
Phase III
Lung cancer trial patients show disparities in optional biospecimen study participation
Who gets left out when cancer patients are asked to donate tissue for research?
An observational analysis of 3017 patients in two phase 3 lung cancer trials found 89% agreed to participate in optional biospecimen studies…
Women and racial minorities in lung cancer trials are less likely to donate tissue samples, risking that future research misses the very peo…
Apr 2, 2026
Pulmonology & Critical Care
Phase II
Phase 2 trial of high-dose thoracic reirradiation shows 30-month median OS for recurrent lung cancer
Can high-dose radiation help when lung cancer returns near where it was treated before?
A phase 2 single-arm trial of 60 patients with recurrent lung cancer in the thorax found that high-dose reirradiation (≥45 Gy EQD) achieved …
When lung cancer returns near a previous radiation site, a precise high-dose treatment helped patients survive a median of 30 months with no…
Apr 2, 2026