Off-pump CABG reduces mortality risk and stroke risk in patients with left ventricular dysfunction
Off-pump heart surgery shows lower death risk for weak hearts
This meta-analysis of 35,863 patients with multivessel coronary artery disease and left ventricular dysfunction (ejection fraction ≤40%) fou…
A large review of over 35,000 patients suggests off-pump heart surgery may reduce mortality and stroke risks for those with weakened heart m…
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Five-year economic and quality of life outcomes favor PCI with zotarolimus stents over CABG in 3-vessel CAD
Five-year follow-up reveals lower costs and better employment for PCI over surgery in complex heart disease
This randomized trial compared fractional flow reserve-guided PCI using zotarolimus drug-eluting stents with coronary artery bypass grafting…
Patients with complex heart disease treated with stents had lower costs and better quality of life than those who had surgery after five yea…
FFR-guided complete revascularization reduces unplanned revascularization in MI patients with multivessel CAD
Complete Heart Repair May Stop Future Emergencies
A meta-analysis of 3,054 patients with myocardial infarction and multivessel coronary artery disease found that FFR-guided complete revascul…
Fixing all blocked heart arteries during surgery may stop future emergencies and unplanned procedures for patients with heart attacks.
Ticagrelor Not Noninferior to Prasugrel in Diabetes Patients With Multivessel CAD After PCI
New study shows ticagrelor did not beat prasugrel for heart attack prevention in diabetics
This randomized clinical trial of 1,800 patients with diabetes and multivessel coronary artery disease undergoing PCI compared ticagrelor pl…
For diabetics with heart stents, a new study found ticagrelor offered no clear advantage over prasugrel in preventing death, heart attacks, …
iFR-guided CABG improves mid-term graft patency versus angiography alone in multivessel disease
Can a simple test during heart surgery help grafts stay open longer?
A single-blinded RCT in patients with multivessel disease and intermediate stenoses found iFR-guided CABG significantly improved LIMA-to-LAD…
A simple pressure test during heart surgery keeps new blood vessel grafts open longer, with 80.5% staying clear versus 56.8% with standard i…
Research across Myocardial ischemia
Related studies from across the Myocardial ischemia family.
Impact of Routine Functional Testing on Clinical Outcomes in Patients with Coronary Artery Disease
Routine Stress Testing Does Not Reduce Heart Risk After Procedure
Routine functional testing at one year post-PCI did not improve clinical outcomes but led to a higher rate of invasive procedures.
Routine stress testing after heart procedures did not lower the risk of death or heart attacks, but it did lead to more invasive medical pro…
Higher Triglyceride-glucose index increases MACE risk in patients undergoing coronary artery bypass grafting
Higher Triglyceride-Glucose Index Linked to Risks After Heart Surgery
This meta-analysis of 5,978 patients found that a higher Triglyceride-glucose index (TyG) is associated with a 62.4% higher hazard of MACE p…
A higher triglyceride-glucose index is linked to a higher risk of major heart events and death in patients following heart bypass surgery.
Functional Coronary Angiography Improves Clinical Outcomes in Multivessel STEMI Patients
Physiology guided heart procedures show lower risk of major events
Physiology-guided revascularization significantly reduces major adverse cardiac events and improves safety profiles compared to traditional …
A large international trial shows that using functional imaging to guide heart artery procedures may lower the risk of stroke and heart atta…
Acupuncture improves cardiac function and reduces MACE risk in patients after percutaneous coronary intervention
Acupuncture shows promise for heart function after coronary procedures
This meta-analysis of 759 patients suggests acupuncture may improve cardiac function and reduce major adverse cardiovascular events followin…
Acupuncture may improve heart function and walking distance for patients recovering from procedures to treat coronary artery disease.
Bayesian analysis of P2Y12 inhibitors identifies clinical uncertainties and equivalence in acute coronary syndromes
Trial Shows Prasugrel May Offer Benefits Over Clopidogrel for Heart Patients
This meta-analysis of 60,619 patients following percutaneous coronary intervention evaluates P2Y12 inhibitors using a Bayesian framework. Th…
A large analysis of over 60,000 patients suggests prasugrel may be more effective than clopidogrel for preventing major heart events after p…
Near-Styloid puncture improves first-attempt success and reduces access-site complications in coronary angiography
Near-Styloid Puncture May Improve Success in Heart Procedures
This randomized controlled trial of 380 patients undergoing coronary angiography found that near-styloid puncture significantly improved fir…
A new puncture location for heart procedures may improve success rates and reduce complications like bruising or artery blockage.
Clopidogrel monotherapy reduces bleeding risk to 2.1% versus 3.2% in patients with acute coronary syndromes
Trial shows clopidogrel alone reduces bleeding risk after heart procedures
This prespecified subgroup analysis of a randomized controlled trial involving 7758 patients with acute coronary syndromes found that clopid…
Patients with heart conditions may face fewer bleeding risks by switching to clopidogrel alone after a period of dual therapy.
Sirolimus-Eluting Balloon with Provisional Stenting for Small to Medium Coronary Arteries
Trial shows sirolimus-eluting balloon is comparable to standard stents
A randomized trial demonstrates that sirolimus-eluting balloon treatment is noninferior to systematic DES for target vessel failure in speci…
A new trial shows that a sirolimus-eluting balloon is as effective as standard stents for treating specific coronary artery blockages.
Evaluating Stepwise Dual Antiplatelet Therapy De-escalation in Patients Following Drug-Coated Balloon Angioplasty
Trial Shows Stepwise DAPT De-escalation for Coronary Heart Disease
A prespecified subgroup analysis of the REC-CAGEFREE II trial evaluates the safety of DAPT de-escalation in ACS patients undergoing DCB-only…
New data shows that switching to a simpler blood thinner regimen may be as safe as standard treatment for patients with coronary artery dise…
Impact of Percutaneous Coronary Intervention Complexity on Ticagrelor or Prasugrel Monotherapy Efficacy
Complex heart procedures do not change risks of certain medications
A post hoc analysis of the NEO-MINDSET trial evaluates if PCI complexity influences the safety and efficacy of potent P2Y inhibitor monother…
New analysis shows that complex heart procedures do not change the safety or effectiveness of specific blood-thinning medications.
Impact of Early Aspirin Withdrawal on Myocardial Infarction in Patients After PCI
Aspirin withdrawal shortly after heart procedures may increase heart attack risk
Early aspirin withdrawal within 30 days post-PCI significantly increases myocardial infarction risk, despite long-term reductions in bleedin…
Stopping aspirin within 30 days of a heart procedure may increase the risk of a heart attack in the first month.
Speckle-tracking echo detects coronary artery disease with 77% sensitivity and 75% specificity
Echocardiography Shows Moderate Accuracy for Detecting Coronary Artery Disease
This meta-analysis of 40 non-randomized studies (5,296 participants) found that speckle-tracking echocardiography (STE) has moderate diagnos…
A review of 40 studies shows that speckle-tracking echocardiography can help identify coronary artery disease with moderate accuracy.
Questions about Multivessel Coronary Artery Disease
Does using FFR guidance reduce the need for repeat heart surgery in multivessel CAD patients?
Using FFR guidance to decide on stenting reduces the need for repeat heart surgery in patients with multivessel coronary artery disease.
Full answer →