Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
Web of White Blood Cells Linked to Pregnancy Risks
A systematic review of emerging evidence indicates that dysregulation of neutrophil extracellular trap (NET) formation and clearance is stro…
A sticky web of white blood cells meant to fight germs can instead trigger serious pregnancy risks like preeclampsia and preterm birth when …
N-acetylcysteine protocol study for early-onset preeclampsia progression in Lagos, Nigeria
NAC study protocol for early-onset preeclampsia in Lagos hospitals planned for 2026 to 2028
This study protocol outlines a planned proof-of-concept trial evaluating daily oral N-acetylcysteine versus placebo in sexually active women…
A planned 2026 trial in Lagos hospitals will test if a daily antioxidant tablet slows the progression of early-onset preeclampsia in pregnan…
Maternal APOL1 risk alleles show no independent association with preeclampsia risk in multi-ethnic study
Study finds no link between maternal APOL1 gene variants and preeclampsia risk
A nested case-control study of 5210 pregnant women found no significant association between maternal APOL1 G1/G2 risk alleles and preeclamps…
A new genetic study of over 5,000 pregnant women found that carrying two APOL1 risk variants did not increase a mother's chance of developin…
Observational report examines hypertensive disorders in pregnancy and mortality at US delivery hospitalizations
U.S. study examines link between high blood pressure in pregnancy and delivery deaths
An observational report analyzed delivery hospitalizations in the United States to examine associations between hypertensive disorders in pr…
High blood pressure during pregnancy is linked to higher death risks at U.S. delivery hospitals, according to a new report.
Higher uric acid-to-creatinine ratio linked to preeclampsia risk in advanced maternal age pregnancy
Higher uric acid ratio linked to increased preeclampsia risk in older pregnant women
A retrospective cohort study of 2,296 pregnant women aged ≥35 years found each standard deviation increase in serum uric acid-to-creatinine …
Older pregnant women with higher uric acid-to-creatinine ratios face 29% greater odds of developing preeclampsia, a serious condition affect…
Meta-Analysis: HS in Pregnancy Linked to Higher Odds of Gestational Diabetes, Preterm Birth, Birth Defects
Does a painful skin condition raise pregnancy risks? A new review finds it's linked to diabetes, pre-eclampsia, and birth defects
A meta-analysis of four retrospective cohort studies (n=15,189,175 pregnancies) found maternal hidradenitis suppurativa (HS) was associated …
Living with hidradenitis suppurativa raises risks for gestational diabetes, pre-eclampsia, and birth defects during pregnancy, according to …
Research across Hypertension
Related studies from across the Hypertension family.
Inflammation and immune dysregulation drive chronic kidney disease progression and associated tissue remodeling
Inflammation and Immune Issues Drive Chronic Kidney Disease Progression
This mini review synthesizes the role of inflammation and immune dysregulation in the initiation and progression of chronic kidney disease. …
Persistent inflammation and immune system issues are central drivers of chronic kidney disease, leading to tissue damage and potential compl…
Neural-immune-cardiovascular axis emerges as therapeutic target in atherosclerosis, hypertension, heart failure
New pathways link nerves and immunity in heart disease
This systematic review synthesizes evidence on the neural-immune-cardiovascular axis in cardiovascular homeostasis and pathogenesis. It exam…
Scientists are mapping how the connection between your nervous system and immune cells may drive conditions like high blood pressure and hea…
Unified cardiometabolic disease framework links T2DM, ASCVD, HFpEF, MASLD, hypertension, and CKD via shared pathophysiology
New Framework Links Heart and Kidney Health in Diabetes
This guideline provides a narrative review of the unified cardiometabolic disease (UCD) continuum. It argues that conditions like T2DM, ASCV…
Experts suggest that diabetes, heart failure, and kidney disease may share a single underlying cause rather than being separate conditions.
21% hypertension prevalence in transgender adults: meta-analysis of cardiovascular morbidities
Transgender adults face high rates of heart disease
This meta-analysis of observational studies reports pooled prevalence of major cardiovascular morbidities among transgender adults aged ≥18 …
One in five transgender adults has high blood pressure, and many have heart disease, a new analysis finds.
Ultra-processed food consumption is associated with higher risk of hypertension and cardiovascular disease
Ultra-processed foods linked to higher risk of heart disease
This systematic review and meta-analysis of 46 studies indicates that higher ultra-processed food (UPF) consumption is associated with a 9% …
Eating more ultra-processed foods is linked to a higher risk of high blood pressure and heart disease in new research.
Triple antihypertensive therapy lowers systolic BP by 5.4 mmHg more than dual therapy
Triple drug therapy lowers blood pressure more than double therapy
This meta-analysis of randomized trials involving 13,461 adults with hypertension found that triple antihypertensive therapy reduced systoli…
Adding a third medication can significantly lower high blood pressure and improve control rates for adults compared to using only two drugs.
Patients with cardiovascular diseases show measurable prevalence of active cancer across multiple conditions
Heart disease patients show measurable risk of developing various cancers
This systematic review and meta-analysis analyzed 4,759,695 patients to determine the prevalence of active cancer in individuals with variou…
New data shows that people with heart conditions like stroke or heart failure have a measurable rate of active cancer cases.
E-Coach WeChat model improves chronic disease self-management scores in hypertension patients
Digital Coaching Improves Management for Patients with Hypertension
This randomized controlled trial of 250 middle-aged and elderly hypertension patients found that the E-Coach platform integrated with WeChat…
A new digital coaching model using a mobile platform helped patients manage hypertension and improve their daily exercise habits.
Genetic Architecture of Pulmonary Artery Diameter and Shared Systemic Vascular Biology
Genetic markers linked to lung artery size in COPD patients
A large-scale meta-analysis identifies 44 independent genetic signals influencing pulmonary artery diameter, highlighting shared pathways wi…
New data links specific genetic markers to the size of pulmonary arteries, potentially helping us understand heart and lung health in COPD.
Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
Better health literacy helps people manage chronic diseases more effectively
This meta-analysis of 138 studies found a moderate positive association (r = 0.29, 95% CI: 0.26-0.31) between health literacy and self-care …
Understanding medical information and using digital tools can help people with chronic conditions like diabetes or heart failure manage thei…
Adverse Childhood Experiences are associated with increased odds of metabolic syndrome and hyperglycemia
Childhood Trauma Linked to Higher Risk of Metabolic Syndrome
This systematic review and meta-analysis of 10 eligible papers found that individuals with at least one Adverse Childhood Experience (ACE) h…
Early childhood trauma is linked to higher risks of high blood pressure, high blood sugar, and other components of metabolic syndrome in adu…
Comparative Efficacy and Safety of Preservative-Free versus Preserved Latanoprost for Glaucoma
Preservative-Free Latanoprost Cuts Eye Redness Risk
A meta-analysis of 1880 eyes compares preservative-free latanoprost to preserved versions, evaluating IOP reduction and ocular surface safet…
A new analysis finds preservative-free latanoprost lowers eye redness risk by 34% while matching standard drops' pressure control after 4 we…
Questions about Pregnancy induced hypertension
Does planned early birth reduce maternal morbidity in late preterm hypertensive disorders of pregnancy?
Planned early birth for late preterm hypertensive disorders reduces maternal morbidity and stillbirth risk compared to waiting longer.
Full answer →What factors predict retinopathy in patients with hypertensive disorders of pregnancy?
Early onset of disease, severe protein in urine, and low red blood cell levels predict retinopathy in hypertensive pregnancy disorders.
Full answer →