High prevalence of vitamin B12 deficiency in South Asian pregnant women suggests risk for adverse outcomes
Vitamin B12 deficiency is common among pregnant women in South Asia
This narrative review examines the prevalence of vitamin B12 deficiency in pregnant women in South Asia and its association with maternal an…
Up to 70% of pregnant women in South Asia may have low vitamin B12, a finding that could impact both mother and baby health.
Gut-placental axis signaling and dysbiosis drive pathological cascades in adverse pregnancy outcomes
Gut Health Links May Help Prevent Pregnancy Complications
This narrative review explores the role of the gut-placental axis in conditions such as preeclampsia and gestational diabetes. The authors s…
New research suggests that the link between gut health and the placenta could help manage risks like preeclampsia and gestational diabetes.
High prenatal allostatic load is associated with increased risk of preeclampsia and preterm birth
High Prenatal Stress Levels Linked to Preeclampsia Risk
This meta-analysis of 8,795 pregnant women found that high prenatal allostatic load (AL) is associated with an increased risk of preeclampsi…
High prenatal allostatic load, a measure of chronic stress, is linked to a higher risk of preeclampsia and preterm birth in pregnant women.
Group prenatal care improves maternal health literacy and reduces gestational diabetes and pre-eclampsia rates
Group Prenatal Care May Lower Risks of Gestational Diabetes
This mini-review examines the impact of group prenatal care on outcomes for pregnant individuals. The authors synthesize evidence that group…
Group prenatal care may improve mental health and lower rates of gestational diabetes and pre-eclampsia for pregnant individuals.
Evaluating Magnesium Sulfate Availability and Utilization for Preeclampsia in Sub-Saharan Africa
Magnesium Sulfate Availability and Use in Sub-Saharan Africa
While magnesium sulfate is available in many rural clinics, significant systemic barriers and underutilization persist in managing preeclamp…
Magnesium sulfate is available in many African clinics, but it is currently underutilized for treating preeclampsia and eclampsia.
sFlt-1/PIGF ratio demonstrates superior diagnostic accuracy for preeclampsia compared to other serum biomarkers
Serum Biomarkers Show Promise for Detecting Preeclampsia
This meta-analysis of 22 studies involving 7,772 participants evaluated the diagnostic performance of various serum biomarkers for preeclamp…
A specific ratio of proteins in the blood may offer high accuracy in identifying preeclampsia during pregnancy, especially in the second tri…
GLP-1 RA exposure in early pregnancy not significantly tied to hypertensive disorders
GLP-1 Medications Show No Link to Pregnancy Hypertension Risk
This meta-analysis of observational cohort studies assessed the risk of hypertensive disorders of pregnancy (HDP) after periconceptional or …
A large review of over 10,000 pregnancies suggests that GLP-1 medications may not increase the risk of high blood pressure during pregnancy.
Sepsis, not breastfeeding, and no KMC significantly increase mortality risk in low birth weight neonates
Several Factors Linked to Higher Mortality in Low Birth Weight Infants
This meta-analysis of observational studies evaluates predictors of mortality in 7539 low birth weight neonates in Ethiopia. The analysis id…
A large meta-analysis identifies several key factors, including sepsis and lack of breastfeeding, linked to higher mortality in low birth we…
Maternal hypertensive disorders of pregnancy are associated with increased offspring asthma risk
Maternal Pregnancy High Blood Pressure Linked to Higher Asthma Risk
This meta-analysis of over three million mother-infant pairs found a significant association between maternal hypertensive disorders of preg…
New data suggests that mothers with high blood pressure during pregnancy may have children at a higher risk for developing asthma.
Structured exercise may improve blood pressure and outcomes in hypertensive disorders of pregnancy
Structured exercise may help manage high blood pressure during pregnancy
This scoping review examines structured exercise interventions, including aerobic training, resistance training, stretching, and yoga, for w…
New research suggests that structured exercises like yoga and resistance training could improve health for pregnant women with high blood pr…
Regulatory T cells are central to immune tolerance and implicated in several pregnancy disorders
Immune cells may play key role in pregnancy complications
This systematic review examines the role of regulatory T cells (Tregs) in maintaining maternal-fetal immune balance. The authors conclude th…
New research highlights how specific immune cells help balance the body during pregnancy and may impact conditions like preeclampsia.
Six paradigm shifts reframe preeclampsia as a first-trimester villous trophoblast syndrome
New Research Reframes the Origins of Preeclampsia
This narrative review synthesizes six inter-related paradigm shifts in placental pathophysiology, reframing preeclampsia as a first-trimeste…
New research suggests preeclampsia begins in the first trimester, potentially allowing for earlier detection and more diverse ways to assess…
Research across Hypertension
Related studies from across the Hypertension family.
Nocturnal hypertension affects 42.5% of population samples, isolated nocturnal hypertension 17.3%
High blood pressure during sleep is common in many people
This meta-analysis estimates the prevalence of nocturnal hypertension and isolated nocturnal hypertension in population-based and community …
Nearly half of people with high blood pressure experience it specifically at night, a finding that helps doctors plan better screening tools…
Study-defined hypertension is not a statistically significant predictor of recurrence in intracranial aneurysms
High blood pressure may not predict aneurysm recurrence after treatment
This systematic review and meta-analysis of 2,442 observations from 8 studies found no statistically significant association between study-d…
New data suggests that a history of high blood pressure does not clearly predict if an aneurysm will return after surgery.
Short-chain fatty acids and intestinal macrophages modulate metabolism in metabolic syndrome and obesity
Short Chain Fatty Acids May Help Manage Metabolic Syndrome
This narrative review explores how short-chain fatty acids (SCFAs) like butyrate, acetate, and propionate influence intestinal macrophage im…
Short-chain fatty acids like butyrate may influence how the body handles inflammation and metabolism in people with obesity and insulin resi…
Gut microbiome dysbiosis may contribute to cognitive decline through neuroinflammation and hypertension-mediated cerebrovascular injury
Gut health and blood pressure may impact brain health
This narrative review explores the gut-brain-vascular axis, proposing that gut microbiome dysbiosis contributes to cognitive decline via neu…
New research explores how an unbalanced gut and high blood pressure might work together to cause brain aging and cognitive decline.
RAAS inhibitors modulate inflammatory responses and oxidative stress across multiple chronic conditions
RAAS Inhibitors May Protect Organs Beyond Lowering Blood Pressure
This systematic review synthesizes the roles of ACEI, ARB, DRI, ARNI, and MRA in modulating inflammatory responses and oxidative stress. The…
New research suggests certain blood pressure medications may protect the heart, kidneys, and lungs by reducing inflammation and oxidative st…
Aerobic Training Lowers Blood Pressure in Hypertension Across 26 Studies
Aerobic training shows significant blood pressure drops for adults
This meta-analysis of 26 studies (1,576 adults with hypertension) found that aerobic training produced statistically significant and clinica…
Aerobic exercise provides meaningful reductions in both systolic and diastolic blood pressure for adults living with hypertension.
KLF1 variants identified in neonate with severe hemolytic anemia and pulmonary hypertension
Genetic testing helps identify a rare cause of severe anemia
This case report and literature review describes a neonate with unexplained Coombs/DAT-negative severe hemolytic anemia, pulmonary hypertens…
A rare genetic variant in the KLF1 gene can cause severe anemia and lung issues in newborns, making early testing vital for accurate diagnos…
AI prescreening tool identifies primary aldosteronism with AUROC 0.709 in hypertension
AI tool helps identify patients with high blood pressure condition
In a retrospective cohort of 22,264 adults with hypertension or PA testing, an AI prescreening tool using EHR data achieved an AUROC of 0.70…
A new AI tool uses electronic health records to help doctors find patients who need testing for a specific heart condition.
Aquatic Exercise Therapy for Blood Pressure Management in Elderly Patients with Hypertension
Pool workouts may lower blood pressure in older adults
Aquatic exercise therapy significantly lowers systolic and diastolic blood pressure in elderly patients, offering a viable non-pharmacologic…
A new analysis finds aquatic exercise may cut systolic blood pressure by about 11 points in older adults with hypertension.
Mineralocorticoid receptor antagonists exert cardioprotective effects by restoring coronary microvascular function
Mineralocorticoid Receptor Antagonists May Improve Heart Function in Heart Failure
This mini-review examines the mechanisms of mineralocorticoid receptor antagonists in patients with heart failure, hypertension, and chronic…
New research highlights how mineralocorticoid receptor antagonists may protect the heart by improving blood flow in small vessels for patien…
One anastomosis gastric bypass provides durable weight loss and metabolic improvements over 15 years
Gastric Bypass Shows Durable Weight Loss and Health Improvements
This meta-analysis of 1729 patients evaluates the long-term outcomes of one anastomosis gastric bypass (OAGB). The analysis indicates durabl…
Gastric bypass surgery can lead to lasting weight loss and improved conditions like diabetes and high blood pressure over 15 years.
Selective aldosterone synthase inhibitors reduce systolic blood pressure by 7.9 mmHg in patients with CKD
Aldosterone Synthase Inhibitors May Lower Blood Pressure in CKD Patients
This meta-analysis of 1148 patients with CKD and uncontrolled hypertension found that selective aldosterone synthase inhibitors (ASIs) reduc…
New research suggests that aldosterone synthase inhibitors could help manage high blood pressure and kidney damage in patients with chronic …
Questions about Pregnancy induced hypertension
Does planned early birth reduce maternal morbidity in late preterm hypertensive disorders of pregnancy?
Planned early birth for late preterm hypertensive disorders reduces maternal morbidity and stillbirth risk compared to waiting longer.
Full answer →What factors predict retinopathy in patients with hypertensive disorders of pregnancy?
Early onset of disease, severe protein in urine, and low red blood cell levels predict retinopathy in hypertensive pregnancy disorders.
Full answer →All Pregnancy induced hypertension Articles
- High prevalence of vitamin B12 deficiency in South Asian pregnant women suggests risk for adverse outcomes
- Gut-placental axis signaling and dysbiosis drive pathological cascades in adverse pregnancy outcomes
- High prenatal allostatic load is associated with increased risk of preeclampsia and preterm birth
- Group prenatal care improves maternal health literacy and reduces gestational diabetes and pre-eclampsia rates
- Evaluating Magnesium Sulfate Availability and Utilization for Preeclampsia in Sub-Saharan Africa
- sFlt-1/PIGF ratio demonstrates superior diagnostic accuracy for preeclampsia compared to other serum biomarkers
- GLP-1 RA exposure in early pregnancy not significantly tied to hypertensive disorders
- Sepsis, not breastfeeding, and no KMC significantly increase mortality risk in low birth weight neonates
- Maternal hypertensive disorders of pregnancy are associated with increased offspring asthma risk
- Structured exercise may improve blood pressure and outcomes in hypertensive disorders of pregnancy
- Regulatory T cells are central to immune tolerance and implicated in several pregnancy disorders
- Six paradigm shifts reframe preeclampsia as a first-trimester villous trophoblast syndrome
- Single-cell RNA sequencing reveals trophoblast and immune mechanisms in preeclampsia pathogenesis
- High sFlt-1 levels correlate with increased PPCM risk in postpartum women
- Lower HDL, higher LDL, TG, TC linked to preeclampsia risk in meta-analysis
- Meta-analysis finds hydroxychloroquine does not reduce most pregnancy complications in SLE
- Planned early birth reduces maternal morbidity and stillbirth risk in late preterm hypertensive disorders of pregnancy
- Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
- Narrative review suggests precision interventions for preeclampsia phenotypes
- Critical review links ADMA levels to endothelial impairment in pregnant women with HIV and preeclampsia in sub-Saharan Africa
- Narrative review on managing hypertriglyceridemia in pregnancy, including olezarsen and volanesorsen
- Study protocol for screening nulliparous women to prevent preeclampsia and fetal growth restriction
- Meta-analysis links high early pregnancy TyG index to increased gestational risks across 23 studies
- Systematic review on neuroimmune mechanisms in preeclampsia
- Cohort study identifies predictors for retinopathy in hypertensive pregnancy disorders
- Early pregnancy serum uric acid levels associated with gestational diabetes risk in cohort study
- Systematic review examines placental biology and social context in Black and African American women with pregnancy complications
- Placental pathology features associated with preterm delivery and adverse outcomes in singleton pregnancies
- Review of Treg-targeting strategies for pregnancy complications lacks reported outcomes or safety data
- Self-reported racial discrimination associated with postpartum depression and low birth weight in pregnant women
- Maternal preeclampsia modestly increases neonatal sepsis risk in infants up to 28 days of age
- Pre-eclampsia history associated with increased subclinical atherosclerosis markers in meta-analysis
- Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
- N-acetylcysteine protocol study for early-onset preeclampsia progression in Lagos, Nigeria
- Maternal APOL1 risk alleles show no independent association with preeclampsia risk in multi-ethnic study
- Observational report examines hypertensive disorders in pregnancy and mortality at US delivery hospitalizations
- Higher uric acid-to-creatinine ratio linked to preeclampsia risk in advanced maternal age pregnancy
- Meta-Analysis: HS in Pregnancy Linked to Higher Odds of Gestational Diabetes, Preterm Birth, Birth Defects