Single-cell RNA sequencing reveals trophoblast and immune mechanisms in preeclampsia pathogenesis
New Sequencing Methods Reveal Hidden Mechanisms of Preeclampsia
This systematic review of single-cell RNA sequencing studies identifies impaired trophoblast differentiation, invasion, and senescence, alon…
Advanced single-cell sequencing reveals how specific cells and molecules contribute to the development of preeclampsia during pregnancy.
High sFlt-1 levels correlate with increased PPCM risk in postpartum women
High sFlt-1 Levels Linked to Risk of Heart Failure
This meta-analysis evaluates the association between circulating sFlt-1 and peripartum cardiomyopathy (PPCM) risk. Findings indicate that hi…
New data shows a link between high sFlt-1 levels and heart muscle damage in women after giving birth, especially those with pre-eclampsia.
Lower HDL, higher LDL, TG, TC linked to preeclampsia risk in meta-analysis
Blood Lipid Levels Linked to Preeclampsia Risk
This meta-analysis of 12 studies found that women with preeclampsia had significantly lower HDL and higher LDL, TG, and TC levels compared t…
Lower HDL and higher LDL, triglycerides, and cholesterol are linked to higher preeclampsia risk, a meta-analysis finds.
Planned early birth reduces maternal morbidity and stillbirth risk in late preterm hypertensive disorders of pregnancy
Planned early birth cuts severe risks for late-term high blood pressure in pregnancy
This Cochrane meta-analysis evaluated planned early birth versus expectant management in 3491 pregnant women with hypertensive disorders fro…
A major review shows planned early birth reduces severe risks for mothers and babies when high blood pressure strikes late in pregnancy.
Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
Adding homocysteine screening helps spot dangerous pregnancy complications earlier
This narrative review evaluates homocysteine combined with multi-index screening for detecting preeclampsia, fetal growth restriction, gesta…
A review suggests adding homocysteine checks to standard tests helps doctors spot risks like preeclampsia and fetal growth restriction more …
Narrative review suggests precision interventions for preeclampsia phenotypes
At-a-Glance
This narrative review examines prevention strategies for preeclampsia in pregnant women. The authors note that standard low-dose aspirin eff…
Preeclampsia prevention is moving beyond aspirin for everyone, with new research showing that matching treatments to a woman's specific risk…
Critical review links ADMA levels to endothelial impairment in pregnant women with HIV and preeclampsia in sub-Saharan Africa
High ADMA Levels Link HIV And Preeclampsia Risks
This critical review examines the role of asymmetric dimethylarginine (ADMA) in women with both preeclampsia and HIV infection in sub-Sahara…
High ADMA levels block blood flow and link HIV infection to dangerous pregnancy complications like preeclampsia in women.
Narrative review on managing hypertriglyceridemia in pregnancy, including olezarsen and volanesorsen
High Triglycerides In Pregnancy Need New Safe Drug Options Soon
This narrative review synthesizes evidence on hypertriglyceridemia in pregnancy. It covers lifestyle and pharmacologic options, noting trigl…
Pregnant women with very high triglycerides face dangerous risks but safe new drugs are not yet approved for use during delivery.
Study protocol for screening nulliparous women to prevent preeclampsia and fetal growth restriction
A new plan to screen for pregnancy risks is being tested in a UK hospital
This study protocol describes a prospective cohort with a nested randomized controlled trial at Rosie Hospital, Cambridge, UK.
A major research plan is starting to test a new way to screen for preeclampsia and fetal growth restriction in pregnant women.
Systematic review on neuroimmune mechanisms in preeclampsia
Preeclampsia: Why Your Brain Matters More Than You Think
This systematic review synthesizes evidence on neuroimmune mechanisms in preeclampsia.
Scientists are finding that nerve signals play a bigger role in pregnancy high blood pressure than we knew.
Meta-analysis links high early pregnancy TyG index to increased gestational risks across 23 studies
Early Blood Test Could Predict Pregnancy Complications Before They Start
This meta-analysis evaluated 23 studies involving 220,985 participants to assess the relationship between high Triglyceride-Glucose (TyG) in…
Checking blood sugar and fat levels early might help prevent serious pregnancy issues.
Cohort study identifies predictors for retinopathy in hypertensive pregnancy disorders
A New Risk Calculator Could Predict Eye Damage in Pregnancy Hypertension
This cohort study analyzed 667 patients with hypertensive disorders of pregnancy to identify predictors for retinopathy.
A new tool uses routine blood pressure and lab tests to spot pregnant patients at highest risk for sight-threatening eye damage from high bl…
Research across Hypertension
Related studies from across the Hypertension family.
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
Ambulatory hypertension in pediatric chronic kidney disease patients increases risk of left ventricular hypertrophy
High Blood Pressure Linked to Heart Changes in Children
This meta-analysis of 51 studies involving 6509 children with chronic kidney disease found that ambulatory hypertension is associated with i…
New data shows a strong link between high blood pressure and heart muscle thickening in children with chronic kidney disease.
Pharmacist-led telepharmacy may improve medication adherence and reduce blood pressure in patients with NCDs
Pharmacist Led Telepharmacy May Improve Medication Adherence For Chronic Illness
This systematic review analyzed 21 trials involving 5440 participants to evaluate pharmacist-led telepharmacy for managing non-communicable …
Remote pharmacist services through phone or video may help patients with high blood pressure and diabetes stick to their daily medication pl…
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
Multi-target therapies may address combined hypertension and dyslipidemia pathophysiology
Multi-Target Therapies May Address Combined Hypertension and High Cholesterol
This systematic review synthesizes evidence on synergistic mechanisms of hypertension and dyslipidemia, highlighting the RAAS/PPAR axis, AMP…
Combining treatments like statins and RAAS inhibitors may offer a more precise way to manage both high blood pressure and cholesterol levels…
Bedtime antihypertensive dosing shows no cardiovascular benefit over morning dosing
Bedtime vs. Morning Blood Pressure Meds: No Clear Winner
A meta-analysis of randomized trials compared bedtime versus morning administration of antihypertensives. No evidence of a difference in maj…
Taking blood pressure medication at bedtime did not reduce heart attacks, strokes, or deaths more than morning dosing in a large analysis of…
Vascular smooth muscle cell immune interactions drive remodeling across cardiovascular diseases
How blood vessel cells drive heart disease and high blood pressure
This narrative review synthesizes mechanisms of VSMC-immune interactions in atherosclerosis, hypertension, aortic aneurysms, and arteritis. …
A new review reveals how blood vessel cells change in heart disease, high blood pressure, and more.
Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
Pre-existing health conditions may slightly reduce weight loss after surgery
A meta-analysis of twenty-three studies reveals that mental illness, diabetes, and sleep apnea are associated with slightly lower weight los…
Adults with mental illness or diabetes before surgery saw slightly less weight loss. Other conditions like high blood pressure did not affec…
Renal denervation value framework prioritizes efficacy and safety for Chinese hospital procurement
Experts build framework to assess renal denervation therapy value in China
This narrative review constructs a comprehensive value assessment framework for renal denervation (RDN) therapy in Chinese hospitals. The fr…
A new framework helps Chinese hospitals evaluate renal denervation therapy by weighing factors like safety, efficacy, and patient value.
Mechanical shear stress influences endothelial RNA methylation in atherosclerosis and pulmonary arterial hypertension
Mechanical forces on blood vessel cells may change how they repair themselves
This narrative review examines the interplay between hemodynamic shear stress and epitranscriptomic mechanisms in endothelial cells. The aut…
New review suggests blood flow forces might alter how RNA works in cells lining our vessels, potentially affecting heart and lung health.
Eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity
Eating later in the day is linked to worse blood sugar and heart health markers
This narrative review examines chrononutrition in obesity, type 2 diabetes, hypertension, and cardiovascular disease. Findings indicate that…
A review suggests eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity in peopl…
Bosentan lowers treatment failure risk in neonates with persistent pulmonary hypertension of the newborn by 73%
Bosentan therapy lowers treatment failure for newborns with persistent lung pressure issues
This systematic review and meta-analysis evaluated bosentan for persistent pulmonary hypertension of the newborn. The pooled analysis showed…
A new analysis shows bosentan therapy reduces treatment failure for newborns with persistent pulmonary hypertension compared to control trea…
Questions about Pregnancy induced hypertension
Does planned early birth reduce maternal morbidity in late preterm hypertensive disorders of pregnancy?
Planned early birth for late preterm hypertensive disorders reduces maternal morbidity and stillbirth risk compared to waiting longer.
Full answer →What factors predict retinopathy in patients with hypertensive disorders of pregnancy?
Early onset of disease, severe protein in urine, and low red blood cell levels predict retinopathy in hypertensive pregnancy disorders.
Full answer →All Pregnancy induced hypertension Articles
- Single-cell RNA sequencing reveals trophoblast and immune mechanisms in preeclampsia pathogenesis
- High sFlt-1 levels correlate with increased PPCM risk in postpartum women
- Lower HDL, higher LDL, TG, TC linked to preeclampsia risk in meta-analysis
- Planned early birth reduces maternal morbidity and stillbirth risk in late preterm hypertensive disorders of pregnancy
- Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
- Narrative review suggests precision interventions for preeclampsia phenotypes
- Critical review links ADMA levels to endothelial impairment in pregnant women with HIV and preeclampsia in sub-Saharan Africa
- Narrative review on managing hypertriglyceridemia in pregnancy, including olezarsen and volanesorsen
- Study protocol for screening nulliparous women to prevent preeclampsia and fetal growth restriction
- Meta-analysis links high early pregnancy TyG index to increased gestational risks across 23 studies
- Systematic review on neuroimmune mechanisms in preeclampsia
- Cohort study identifies predictors for retinopathy in hypertensive pregnancy disorders
- Early pregnancy serum uric acid levels associated with gestational diabetes risk in cohort study
- Systematic review examines placental biology and social context in Black and African American women with pregnancy complications
- Placental pathology features associated with preterm delivery and adverse outcomes in singleton pregnancies
- Review of Treg-targeting strategies for pregnancy complications lacks reported outcomes or safety data
- Self-reported racial discrimination associated with postpartum depression and low birth weight in pregnant women
- Maternal preeclampsia modestly increases neonatal sepsis risk in infants up to 28 days of age
- Pre-eclampsia history associated with increased subclinical atherosclerosis markers in meta-analysis
- Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
- N-acetylcysteine protocol study for early-onset preeclampsia progression in Lagos, Nigeria
- Maternal APOL1 risk alleles show no independent association with preeclampsia risk in multi-ethnic study
- Observational report examines hypertensive disorders in pregnancy and mortality at US delivery hospitalizations
- Higher uric acid-to-creatinine ratio linked to preeclampsia risk in advanced maternal age pregnancy
- Meta-Analysis: HS in Pregnancy Linked to Higher Odds of Gestational Diabetes, Preterm Birth, Birth Defects