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Seasonal allergic rhinitis

Part of Allergic Rhinitis

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for seasonal allergic rhinitis

81 trials tracked for seasonal allergic rhinitis: 62 in phase 3 or 4 and 4 with published results. The most-cited published study has 55 citations.

81Trials tracked
62Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 16 Phase 3 46 Phase 2 11 Phase 1 2 Other / NA 6
  1. Phase 3 Efficacy and Safety Study of RAGWITEK™ (MK-3641) in Children With Ragweed-Induced Rhinoconjunctivitis With or Without Asthma (MK-3641-008) Completed · 55 cited
  2. Phase 3 Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR) Completed · 43 cited
  3. Phase 3 An Exploratory Study of PQ Grass 27600 SU Completed · 1 cited
  4. Phase 3 Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen Completed · 1 cited
  5. Phase 4 Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine Completed
  6. Phase 4 Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis Completed
Show 44 more trials
  1. Phase 4 Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects Completed
  2. Phase 4 Nasonex Compared With Placebo in Participants With Seasonal Allergic Rhinitis (SAR) and Concomitant Asthma (P03280) Completed
  3. Phase 4 Allergic Rhinitis Changes the Sinus Microbiome Completed
  4. Phase 4 Dymista Allergen Chamber - Onset of Action Study Completed
  5. Phase 4 Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial Completed
  6. Phase 4 Comparison of Seasonal Allergic Rhinitis Treatment With 2 Antihistamines Used in Combination With Intranasal Corticosteroid Completed
  7. Phase 4 A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis Completed
  8. Phase 4 Vitamin D Plus Fluticasone Propionate Completed
  9. Phase 4 Effect of Veramyst and Olopatadine 0.2% Opthalmic Solution on Allergy Symptoms Completed
  10. Phase 4 Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine Completed
  11. Phase 4 Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED) Completed
  12. Phase 4 Safety Study of MK-3641 and MK-7243 Co-administered in Adult Participants With Ragweed and Grass Pollen Induced Allergic Rhinitis (P08607, MK-3641-006) Completed
  13. Phase 4 This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED) Completed
  14. Phase 4 A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis Completed
  15. Phase 3 Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204) Completed
  16. Phase 3 Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia Completed
  17. Phase 3 Safety and Efficacy of Mometasone Furoate (SCH 032088) vs Beclomethasone Dipropionate or Placebo in Seasonal Allergic Rhinitis (C93-013) Completed
  18. Phase 3 Dose-Ranging Study of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray in the Treatment of Children (Ages 6-11) With Seasonal Allergic Rhinitis (C95-161) Completed
  19. Phase 3 Mometasone Furoate Aqueous (MK-0887/SCH 032088) Nasal Spray vs Placebo and FLONASE® in Seasonal Allergic Rhinitis Patients (I94-001) Completed
  20. Phase 3 Onset of Action of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray Compared With Placebo in Seasonal Allergic Rhinitis (C93-184) Completed
  21. Phase 3 Study of Efficacy and Safety of Omalizumab in Severe Japanese Cedar Pollinosis Adult and Adolescent Patients Completed
  22. Phase 3 Clinical Equivalence Study of Mometasone Nasal Spray Completed
  23. Phase 3 A Study Comparing the Clinical Equivalence of Two Mometasone Nasal Sprays in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis Completed
  24. Phase 3 A Study Comparing Two Fluticasone Furoate Nasal Sprays in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis Completed
  25. Phase 3 Comparative Safety and Efficacy of Two Steroid Treatments in the Relief of the Symptoms of Seasonal Allergic Rhinitis Completed
  26. Phase 3 A Placebo-controlled Study of 2-day Pre-treatment With Fexofenadine in Seasonal Allergic Rhinitis Completed
  27. Phase 3 A Study Investigating the Effect of Montelukast in Patients With Seasonal Allergic Rhinitis (MK-0476-192)(COMPLETED) Completed
  28. Phase 3 A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Seasonal Allergic Rhinitis (SAR) Completed
  29. Phase 3 Placebo-Controlled Study of Mometasone Furoate Nasal Spray (MFNS) 200 mcg QD in the Treatment of Seasonal Allergic Rhinitis (Study P05106)(COMPLETED) Completed
  30. Phase 3 Safety and Efficacy Trial of Dymista Nasal Spray in Children Ages 4 to 11 With Seasonal Allergic Rhinitis (SAR) Completed
  31. Phase 3 A Study Comparing Montelukast With Placebo in Children With Seasonal Allergic Rhinitis (0476-219)(COMPLETED) Completed
  32. Phase 3 Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR) Completed
  33. Phase 3 A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies Completed
  34. Phase 3 A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies Completed
  35. Phase 3 The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR)(P04579) Completed
  36. Phase 3 Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED) Completed
  37. Phase 3 A Study to Evaluate the Safety & Effectiveness of a Nasal Spray to Treat Seasonal Allergies Completed
  38. Phase 3 Safety and Efficacy of Olopatadine HCl Nasal Spray in 6-11 Year Old Patients Completed
  39. Phase 3 Study of the Efficacy and Safety of MK-0476 in Japanese Pediatric Participants With Seasonal Allergic Rhinitis (MK-0476-519) Completed
  40. Phase 3 Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis (SAR) to Mountain Cedar in Subjects 12 Years and Older Completed
  41. Phase 3 Study of an Investigational Nasal Aerosol or Placebo Nasal Aerosol in Children (Ages 6-11) With Seasonal Allergies Completed
  42. Phase 3 Assessment of Fluticasone Propionate on Ocular Allergy Symptoms Completed
  43. Phase 3 Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis Completed
  44. Phase 3 A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies Completed

Showing the 50 most-cited and recently-updated of 81 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Allergic Rhinitis

Related studies from across the Allergic Rhinitis family.

Astragali Radix metabolites show anti-inflammatory and immunomodulatory activities for allergic respiratory conditions
Drug Pipeline Sys. Review
Astragali Radix metabolites show anti-inflammatory and immunomodulatory activities for allergic respiratory conditions Astragali Radix metabolites show promise for allergic airway diseases
This narrative review examines the potential of Astragali Radix metabolites, including polysaccharides, saponins, and flavonoids, for allerg…
A review suggests Astragali Radix metabolites may help treat allergic asthma and related conditions through anti-inflammatory and immunomodu…
Early preterm birth linked to lower atopic dermatitis risk in large meta-analysis
Dermatology Meta-analysis
Early preterm birth linked to lower atopic dermatitis risk in large meta-analysis Preterm birth linked to lower allergy risk in children
A meta-analysis of observational studies involving over 5 million children found that early preterm birth was associated with a reduced risk…
Babies born early may have lower odds of developing eczema and hay fever, a large analysis finds.
Botulinum toxin type A improves nasal symptoms in refractory allergic rhinitis with SMD -2.07 at 4 weeks
Allergy & Immunology Meta-analysis
Botulinum toxin type A improves nasal symptoms in refractory allergic rhinitis with SMD -2.07 at 4 weeks Botox helps stubborn nasal allergies, review finds
This meta-analysis of 187 patients with refractory allergic rhinitis found that botulinum toxin type A significantly improved total nasal sy…
For people with nasal allergies that won't quit, a review suggests Botox shots may ease symptoms as well as standard steroid injections or p…
Probiotics reduce nasal and eye symptom scores in children with allergic rhinitis
Allergy & Immunology Meta-analysis
Probiotics reduce nasal and eye symptom scores in children with allergic rhinitis Probiotics may help children with allergic rhinitis nasal and eye symptoms
This systematic review and meta-analysis of 1,739 children found that probiotics, prebiotics, or synbiotics significantly reduced nasal and …
A large review found that probiotics, prebiotics, or synbiotics reduced nasal and eye symptoms in children with allergic rhinitis compared t…
Systematic review and meta-analysis of Xiangju capsules for allergic rhinitis symptoms and immunology
Drug Pipeline Meta-analysis
Systematic review and meta-analysis of Xiangju capsules for allergic rhinitis symptoms and immunology Xiangju Capsules Show Higher Effectiveness for Allergic Rhinitis Symptoms
This systematic review and meta-analysis synthesized evidence on Xiangju capsules for allergic rhinitis. It found a higher overall effective…
A meta-analysis of 1,968 patients found Xiangju capsules improved symptom scores and immune markers compared to conventional treatment alone…
Systematic review and meta-analysis of adherence to intranasal corticosteroids and oral antihistamines in adults with allergic rhinitis
Allergy & Immunology Meta-analysis
Systematic review and meta-analysis of adherence to intranasal corticosteroids and oral antihistamines in adults with allergic rhinitis Most People With Allergies Skip Their Meds, New Data Shows
This systematic review and meta-analysis evaluated adherence to intranasal corticosteroids and oral antihistamines among 191,103 adults with…
If you have hay fever and sometimes skip your allergy spray or pill, you are far from alone: a new analysis of nearly 200,000 patients finds…
Meta-analysis on SPG acupuncture for allergic rhinitis quality of life and symptom scores
Allergy & Immunology Meta-analysis
Meta-analysis on SPG acupuncture for allergic rhinitis quality of life and symptom scores Acupuncture at a Facial Nerve Point Eases Allergy Symptoms and Improves Life Quality
This meta-analysis of 732 patients with allergic rhinitis found that sphenopalatine ganglion acupuncture improved quality of life and nasal …
Acupuncture near a facial nerve bundle eases allergy symptoms and improves daily life for people with allergic rhinitis.
Montelukast and oral antihistamines improve daytime allergic rhinitis symptoms
Allergy & Immunology Meta-analysis
Montelukast and oral antihistamines improve daytime allergic rhinitis symptoms Combination therapy beats single drug for daytime allergy symptoms
A meta-analysis finds combination therapy significantly improves daytime symptoms in allergic rhinitis, with limited benefits for nighttime …
Combining two common allergy drugs works better for daytime relief than taking just one, but the extra pill might not help you sleep at nigh…
Systematic review and meta-analysis links swimming pool attendance to increased asthma risk in children
Allergy & Immunology Meta-analysis
Systematic review and meta-analysis links swimming pool attendance to increased asthma risk in children Swimming Pool Time May Raise Asthma Risk For Kids
This systematic review and meta-analysis evaluated the association between swimming pool attendance and the risk of allergic diseases in 54,…
New research shows swimming pool attendance may increase asthma risk for children but does not appear to affect other common allergies.
Systematic review on allergic rhinitis links environmental exposures and microbiome changes
Allergy & Immunology Sys. Review
Systematic review on allergic rhinitis links environmental exposures and microbiome changes Researchers find environment and microbes shape allergy risk
This systematic review synthesizes evidence on environmental exposures and the microbiome in allergic rhinitis.
Air pollution, early antibiotics, and farm life may change your nasal microbes, raising or lowering allergy risk, a new review suggests.
Serum specific IgE testing reveals dust mite sensitization in 37.0% of patients with allergic diseases in Ningbo, China
Primary Care & Family Medicine Cohort
Serum specific IgE testing reveals dust mite sensitization in 37.0% of patients with allergic diseases in Ningbo, China Dust mites top allergen list in large Chinese patient cohort
This cohort study of 19,787 patients with suspected allergic diseases undergoing serum specific IgE testing in Ningbo, China, identified dus…
In a study of nearly 20,000 patients, dust mites were the most common allergen causing sensitization, followed by milk and mixed grasses.
Peri- and postmenopausal hormonal changes may exacerbate asthma, rhinitis, cough, allergies, hypersensitivity, anaphylaxis, and angioedema
Allergy & Immunology Sys. Review
Peri- and postmenopausal hormonal changes may exacerbate asthma, rhinitis, cough, allergies, hypersensitivity, anaphylaxis, and angioedema Menopause Changes Allergy Rules for Women
This systematic review examines the association between declining and fluctuating estrogen and progesterone levels and various allergic and …
Menopause can worsen allergies like hay fever and asthma because dropping estrogen levels make your immune system more reactive to triggers.