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Home › Conditions › Allergic Rhinitis

Allergic Rhinitis

Subtypes of Allergic Rhinitis

Hay Fever 2 House dust mite allergy 1 Seasonal allergic rhinitis 1

25 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Allergic Rhinitis

73 trials tracked for Allergic Rhinitis: 40 in phase 3 or 4 and 4 with published results. The most-cited published study has 206 citations.

73Trials tracked
40Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 17 Phase 3 23 Phase 2 13 Phase 1 6 Other / NA 14
  1. Phase 3 Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis Completed · 206 cited
  2. Phase 4 Safety Study of Levocetirizine and Fexofenadine Completed · 20 cited
  3. Phase 4 A Study to Compare the Efficacy and Safety of Fluticasone Furoate Nasal Sprays (FFNS) 55 Microgram (mcg) and 110 mcg in Chinese Pediatric Subjects With Allergic Rhinitis (AR) Completed · 16 cited
  4. Phase 4 Comparison Between Systemic Exposure to Ciclesonide Nasal Spray, Ciclesonide HFA Nasal Aerosol and Orally Inhaled Ciclesonide (BY9010/M1-422) Completed · 15 cited
  5. Phase 4 Effects of Bilastine on F1 Simulator Driving Performance in Patients Affected by Allergic Rhinitis and/or Urticaria Completed
  6. Phase 4 Comparability and Standardization of Controlled Allergen Challenge Facilities Completed
Show 44 more trials
  1. Phase 4 Sunovion Growth Study Pediatric Subjects With Mild Asthma & Allergic Rhinitis Completed
  2. Phase 4 A Study to Evaluate Cooling Sensation of an Allergy Product in Adults With a History of Allergies Completed
  3. Phase 4 An Allergen BioCube (ABC) Study Evaluating the Efficacy of Fluticasone Propionate Nasal Spray Compared to Placebo Completed
  4. Phase 4 Immunologic Basis of Anti-IgE Therapy (Study II: On Patients With Asthma) Completed
  5. Phase 4 Factors Involved in Dymista's Superior Clinical Efficacy in the Treatment of Seasonal Allergic Rhinitis Completed
  6. Phase 4 Safety of Astepro 0.15% Nasal Spray and Astepro 0.1% Nasal Spray in Children Ages >6 Months to <6 Years With AR Completed
  7. Phase 4 Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen Completed
  8. Phase 4 Intranasal Steroids and Oxymetazoline in Allergic Rhinitis Completed
  9. Phase 4 Is Levocetirizine Less Sedating Than Cetirizine? Completed
  10. Phase 4 Evaluation of the Sensory Attributes of Olopatadine 0.6% and Azelastine 137mcg Nasal Sprays in Patients w/Allergic Rhinitis Completed
  11. Phase 4 Montelukast in Mild Asthmatic Children With Allergic Rhinitis (0476-367) Completed
  12. Phase 4 A Randomised, Double Blind, Placebo Controlled, 4 Period, Incomplete Block, Crossover Study Assessing the Dose-response Curve of Fluticasone Propionate in an Antigen Challenge Chamber Completed
  13. Phase 3 Efficacy and Safety Trial of Pangramin SLIT HDM-mix in Subjects With House Dust Mite Induced Rhinitis Completed
  14. Phase 3 Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145) Completed
  15. Phase 3 Study to Assess the Efficacy of Anti-Bet v 1 Monoclonal Antibodies in Adults to Reduce Symptoms of Seasonal Allergic Rhinitis Completed
  16. Phase 3 Adolescent Mite Allergy Safety Evaluation Completed
  17. Phase 3 An Exploratory Study of Nasonex in Patients With Moderate to Severe Persistent Allergic Rhinitis and Intermittent Asthma Completed
  18. Phase 3 Efficacy and Long-Term Safety of Ragweed (Ambrosia Artemisiifolia) Sublingual Tablet (SCH 39641) in Adults With a History of Ragweed-Induced Rhinoconjunctivitis With or Without Asthma (Study P05234) Completed
  19. Phase 3 A 6 Month Safety and Efficacy Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) in the Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older Completed
  20. Phase 3 3 Month Safety Study of Dymista Nasal Spray and Fluticasone Propionate in Children 4-11 Years of Age With Allergic Rhinitis Completed
  21. Phase 3 Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin Completed
  22. Phase 3 Topical ASP-1001 (Contrast Media Formulation) and the Acute Response to Nasal Allergen Challenge (NAC) Completed
  23. Phase 3 Hypothalamic-Pituitary-Adrenal (HPA)-Axis Study in Pediatric Subjects With Perennial Allergic Rhinitis (PAR) Completed
  24. Phase 3 Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05528)(COMPLETED) Completed
  25. Phase 3 Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 6 Months to 11 Months Completed
  26. Phase 3 Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529) Completed
  27. Phase 3 Assessment of Fluticasone Propionate on Ocular Allergy Symptoms Completed
  28. Phase 3 A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484) Completed
  29. Phase 3 A Study of SCH 697243 in Participants With Grass Pollen Allergy Symptoms, With or Without Asthma (P08067) Completed
  30. Phase 3 A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Fluticasone Furoate Nasal Spray for 2 Weeks in Chinese Adult and Adolescent Subjects With Allergic Rhinitis Completed
  31. Phase 3 Efficacy Study of Sublingual Immunotherapy to Treat Ragweed Allergies Completed
  32. Phase 3 Study for the Treatment of Persistent Allergic Rhinitis With Desloratadine (Study P04684) Completed
  33. Phase 3 Study of an Investigational Nasal Aerosol or Placebo in Children (Ages 4 to 11) With Perennial Allergic Rhinitis (PAR) Completed
  34. Phase 3 Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05583) Completed
  35. Phase 2 Grass Pollen Allergen Immunotherapy Tablet (AIT) Time Course Study Completed
  36. Phase 2 Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants Completed
  37. Phase 2 Dupilumab As An Adjunct For Subcutaneous Grass Immunotherapy Completed
  38. Phase 2 Efficacy Study in Allergic Rhinitis Patients After Intranasal Administration of AZD8848 Completed
  39. Phase 2 Clinical Response to Rhinovirus Challenge Completed
  40. Phase 2 A Novel Biologic Therapy for Perennial Allergic Rhinitis Completed
  41. Phase 2 Efficacy Study of a Preseasonal Treatment With AllerT in Subjects With Birch Pollen Allergy Completed
  42. Phase 2 Effects of Broccoli Sprout Extract on Allergy Rhinitis Completed
  43. Phase 2 Efficacy and Safety of SUBLIVAC Phleum for Immunotherapy of Grass Pollen-Allergy Completed
  44. Phase 2 Safety and Pharmacokinetics of Patanase in Pediatric Patients 2 to < 6 Years of Age Completed

Showing the 50 most-cited and recently-updated of 73 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Astragali Radix metabolites show anti-inflammatory and immunomodulatory activities for allergic respiratory conditions
Drug Pipeline Sys. Review
Astragali Radix metabolites show anti-inflammatory and immunomodulatory activities for allergic respiratory conditions Astragali Radix metabolites show promise for allergic airway diseases
This narrative review examines the potential of Astragali Radix metabolites, including polysaccharides, saponins, and flavonoids, for allerg…
A review suggests Astragali Radix metabolites may help treat allergic asthma and related conditions through anti-inflammatory and immunomodu…
Frontiers Jun 3, 2026
Early preterm birth linked to lower atopic dermatitis risk in large meta-analysis
Dermatology Meta-analysis
Early preterm birth linked to lower atopic dermatitis risk in large meta-analysis Preterm birth linked to lower allergy risk in children
A meta-analysis of observational studies involving over 5 million children found that early preterm birth was associated with a reduced risk…
Babies born early may have lower odds of developing eczema and hay fever, a large analysis finds.
Jun 1, 2026
Botulinum toxin type A improves nasal symptoms in refractory allergic rhinitis with SMD -2.07 at 4 weeks
Allergy & Immunology Meta-analysis
Botulinum toxin type A improves nasal symptoms in refractory allergic rhinitis with SMD -2.07 at 4 weeks Botox helps stubborn nasal allergies, review finds
This meta-analysis of 187 patients with refractory allergic rhinitis found that botulinum toxin type A significantly improved total nasal sy…
For people with nasal allergies that won't quit, a review suggests Botox shots may ease symptoms as well as standard steroid injections or p…
Jun 1, 2026
Probiotics reduce nasal and eye symptom scores in children with allergic rhinitis
Allergy & Immunology Meta-analysis
Probiotics reduce nasal and eye symptom scores in children with allergic rhinitis Probiotics may help children with allergic rhinitis nasal and eye symptoms
This systematic review and meta-analysis of 1,739 children found that probiotics, prebiotics, or synbiotics significantly reduced nasal and …
A large review found that probiotics, prebiotics, or synbiotics reduced nasal and eye symptoms in children with allergic rhinitis compared t…
May 29, 2026
Systematic review and meta-analysis of Xiangju capsules for allergic rhinitis symptoms and immunology
Drug Pipeline Meta-analysis
Systematic review and meta-analysis of Xiangju capsules for allergic rhinitis symptoms and immunology Xiangju Capsules Show Higher Effectiveness for Allergic Rhinitis Symptoms
This systematic review and meta-analysis synthesized evidence on Xiangju capsules for allergic rhinitis. It found a higher overall effective…
A meta-analysis of 1,968 patients found Xiangju capsules improved symptom scores and immune markers compared to conventional treatment alone…
Frontiers May 28, 2026
Narrative review highlights diagnostic gaps for house dust mite allergy in tropical regions
Allergy & Immunology Sys. Review
Narrative review highlights diagnostic gaps for house dust mite allergy in tropical regions Understanding house dust mite allergy challenges in tropical regions for better patient care
This narrative review examines house dust mite allergy in populations living in tropical regions. The authors note that significant knowledg…
This review highlights how house dust mites cause allergies differently in tropical areas. Experts say current tools often miss these unique…
Frontiers May 21, 2026
Systematic review and meta-analysis of adherence to intranasal corticosteroids and oral antihistamines in adults with allergic rhinitis
Allergy & Immunology Meta-analysis
Systematic review and meta-analysis of adherence to intranasal corticosteroids and oral antihistamines in adults with allergic rhinitis Most People With Allergies Skip Their Meds, New Data Shows
This systematic review and meta-analysis evaluated adherence to intranasal corticosteroids and oral antihistamines among 191,103 adults with…
If you have hay fever and sometimes skip your allergy spray or pill, you are far from alone: a new analysis of nearly 200,000 patients finds…
May 14, 2026
Meta-analysis on SPG acupuncture for allergic rhinitis quality of life and symptom scores
Allergy & Immunology Meta-analysis
Meta-analysis on SPG acupuncture for allergic rhinitis quality of life and symptom scores Acupuncture at a Facial Nerve Point Eases Allergy Symptoms and Improves Life Quality
This meta-analysis of 732 patients with allergic rhinitis found that sphenopalatine ganglion acupuncture improved quality of life and nasal …
Acupuncture near a facial nerve bundle eases allergy symptoms and improves daily life for people with allergic rhinitis.
Frontiers May 13, 2026
Montelukast and oral antihistamines improve daytime allergic rhinitis symptoms
Allergy & Immunology Meta-analysis
Montelukast and oral antihistamines improve daytime allergic rhinitis symptoms Combination therapy beats single drug for daytime allergy symptoms
A meta-analysis finds combination therapy significantly improves daytime symptoms in allergic rhinitis, with limited benefits for nighttime …
Combining two common allergy drugs works better for daytime relief than taking just one, but the extra pill might not help you sleep at nigh…
May 5, 2026
Systematic review and meta-analysis links swimming pool attendance to increased asthma risk in children
Allergy & Immunology Meta-analysis
Systematic review and meta-analysis links swimming pool attendance to increased asthma risk in children Swimming Pool Time May Raise Asthma Risk For Kids
This systematic review and meta-analysis evaluated the association between swimming pool attendance and the risk of allergic diseases in 54,…
New research shows swimming pool attendance may increase asthma risk for children but does not appear to affect other common allergies.
May 1, 2026
Systematic review on allergic rhinitis links environmental exposures and microbiome changes
Allergy & Immunology Sys. Review
Systematic review on allergic rhinitis links environmental exposures and microbiome changes Researchers find environment and microbes shape allergy risk
This systematic review synthesizes evidence on environmental exposures and the microbiome in allergic rhinitis.
Air pollution, early antibiotics, and farm life may change your nasal microbes, raising or lowering allergy risk, a new review suggests.
Frontiers Apr 28, 2026
Serum specific IgE testing reveals dust mite sensitization in 37.0% of patients with allergic diseases in Ningbo, China
Primary Care & Family Medicine Cohort
Serum specific IgE testing reveals dust mite sensitization in 37.0% of patients with allergic diseases in Ningbo, China Dust mites top allergen list in large Chinese patient cohort
This cohort study of 19,787 patients with suspected allergic diseases undergoing serum specific IgE testing in Ningbo, China, identified dus…
In a study of nearly 20,000 patients, dust mites were the most common allergen causing sensitization, followed by milk and mixed grasses.
Frontiers Apr 24, 2026

Questions about Allergic Rhinitis

Do hormonal changes during menopause make allergic rhinitis symptoms worse?

Yes, hormonal changes during menopause may worsen allergic rhinitis symptoms by affecting immune and nasal tissue responses, though evidence is limited.

Full answer →
How do environmental exposures and microbiome changes affect allergic rhinitis?

Environmental exposures like air pollution and climate change disrupt the nasal microbiome and epithelial barrier, increasing allergic rhinitis risk, while microbial changes (dysbiosis) promote inflammation.

Full answer →
Can swimming pool attendance increase the risk of allergic rhinitis in children?

Current evidence does not show that swimming pool attendance increases the risk of allergic rhinitis in children; some studies even suggest a protective effect.

Full answer →

All Allergic Rhinitis Articles