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Ophthalmology
Meta-analysis
Ethambutol optic neuropathy incidence 1.54 percent with renal impairment and hypertension as key risk factors
Kidney disease and high blood pressure raise risk of vision loss from TB drug
This systematic review and meta-analysis synthesized evidence on ethambutol optic neuropathy and tuberculous meningitis complications. The p…
A massive review of over 260,000 patients found that kidney problems and high blood pressure make vision loss from the TB drug ethambutol mu…
Frontiers
May 29, 2026
Neurology
RCT
Cerebral infarction common in tuberculous meningitis and linked to disease severity and arterial occlusion
Could blood thinners or specific treatments make brain strokes worse in severe meningitis?
This secondary analysis of the ACT-TBM randomized trial examined 226 patients with tuberculous meningitis at two tertiary centers in India.
Patients with tuberculous meningitis and blocked arteries were much more likely to develop strokes, especially if they received modified tub…
Apr 15, 2026
Infectious Disease
RCT
Contezolid Shows Lower CSF Concentrations Than Linezolid in Tuberculous Meningitis
New Drug Reaches Brain in Tuberculosis Fight
A small randomized study in 10 tuberculous meningitis patients compared CSF concentrations of contezolid versus linezolid.
A new tuberculosis drug reaches the brain effectively and safely, offering hope for the deadliest form of the infection.
Apr 11, 2026