Narrative review discusses CAR-T and HSC therapies for cancer and autoimmune conditions
Cancer Cell Therapy Gets Second Life Against Diabetes and MS
This narrative review examines the scope of chimeric antigen receptor T-cell (CAR-T), CAR-engineered regulatory T cell (CAR-Treg), and hemat…
• CAR-T cells trained to calm overactive immune systems show real promise • People with Type 1 diabetes or multiple sclerosis could benefit …
Systematic review and meta-analysis of integrative therapies for Type 1 Diabetes Mellitus
Yoga and Natural Therapies Help Control Type 1 Diabetes
This meta-analysis of 12 studies on integrative therapies for Type 1 Diabetes Mellitus found adjunctive benefits for glycemic control.
It’s 6 a.m. and 12-year-old Maya stirs awake.
Autoimmune Thyroiditis Prevalence Higher in Obese Women With PCOS in Retrospective Cohort Analysis
New PCOS Data Reveals Hidden Thyroid Risks
This retrospective cohort study evaluated 1,249 women with PCOS aged 18–44 years.
Women with PCOS should check their thyroid health regularly.
Machine learning model predicts in-hospital hypoglycemia in Chinese adults with type 1 diabetes
New AI Model Predicts Dangerous Blood Sugar Drops in Hospital
This retrospective cohort study of 1498 adult inpatients with type 1 diabetes in China developed a machine learning model to predict in-hosp…
This new tool could give doctors an early warning system to prevent dangerous blood sugar drops before they happen, making hospital stays sa…
Cadonilimab therapy in cervical cancer associated with new-onset type 1 diabetes and diabetic ketoacidosis in a case report
A Cancer Drug Triggered Sudden Diabetes in an 81-Year-Old
This systematic review includes a case report of an 81-year-old female with cervical squamous cell carcinoma who developed diabetic ketoacid…
A powerful cancer drug can switch off the body's insulin supply almost overnight, causing sudden, life-threatening diabetes in patients with…
Chinese APS-1 patients show recurrent AIRE gene deletion, male predominance, and low classic triad incidence
What makes autoimmune syndrome APS-1 different in Chinese patients?
A case report and systematic narrative review of 25 genetically confirmed Chinese APS-1 patients identified a recurrent deletion of AIRE gen…
A new look at 25 genetically confirmed Chinese patients with APS-1 found a specific AIRE gene deletion and a surprising trend where twice as…
Research across Type 1 Diabetes
Related studies from across the Type 1 Diabetes family.
Pancreatic tissue engineering faces vascularization hurdle in type 1 diabetes therapy
New tissue engineering methods aim to improve pancreatic transplants
This narrative review examines pancreatic tissue engineering for type 1 diabetes, highlighting insufficient vascularization as the dominant …
Current pancreas transplants are limited by a shortage of donors and the need for lifelong drugs. New engineering techniques may offer a dif…
CAR technology for autoimmune disorders, infectious diseases, fibrotic lesions, inflammatory bowel disease, and type 1 diabetes is reviewed
Chimeric antigen receptor technology may help treat autoimmune disorders and other conditions
This narrative review discusses the application of chimeric antigen receptor (CAR) technology across autoimmune disorders, infectious diseas…
A narrative review suggests chimeric antigen receptor technology could be useful for treating autoimmune disorders, infectious diseases, and…
scFv-based biologics show potential for immunomodulation in type 1 and type 2 diabetes
Review explores scFv biologics for Type 1 and Type 2 diabetes care
This narrative review explores the potential of single-chain variable fragment (scFv)-based biologics for treating type 1 and type 2 diabete…
This review looks at scFv-based biologics for diabetes. It discusses how these treatments might help with immune control and blood sugar bal…
Meta-analysis finds no link between early-life antibiotics and type 1 diabetes risk
Antibiotics in Pregnancy Don’t Raise Child’s Diabetes Risk, Study Finds
This meta-analysis of early-life antibiotic exposure found no significant association with type 1 diabetes incidence in the general populati…
This large review offers reassurance that standard antibiotic use during pregnancy and infancy is safe regarding type 1 diabetes risk, with …
Early-life antibiotic exposure linked to modest increased risk of childhood type 1 diabetes
Meta-analysis links early-life antibiotic use to higher childhood type 1 diabetes risk
This meta-analysis of early-life antibiotic use found a modest increased risk of childhood type 1 diabetes. Prenatal exposure showed a poole…
A large meta-analysis suggests early antibiotic exposure may slightly raise childhood type 1 diabetes risk, though causality remains unclear…
Women with Type 1 Diabetes have a 2.10 times higher risk of female sexual dysfunction compared to age-matched controls
Women with Type 1 Diabetes face a higher risk of sexual dysfunction than controls
This systematic review and meta-analysis evaluated the prevalence and risk of female sexual dysfunction in women with Type 1 Diabetes. The p…
A large review found that women with Type 1 Diabetes are significantly more likely to experience sexual dysfunction compared to healthy wome…
Systematic review and meta-analysis on probiotics for glycemic control in pediatric type 1 diabetes
New review shows probiotics may help lower blood sugar levels in kids with type 1 diabetes
This systematic review and meta-analysis synthesized evidence on oral probiotics, prebiotics, or synbiotics in children and adolescents with…
A study of 808 children found that taking probiotics helped lower blood sugar and A1C levels. More research is needed to find the best type …
Case report of high-dose ceftazidime in an 84-year-old man with skull base osteomyelitis and type 1 diabetes
High-dose antibiotic shows partial skull base infection resolution
This case report describes an 84-year-old man with type 1 diabetes, vascular comorbidity, and advanced frailty treated for skull base osteom…
An 84-year-old man with diabetes and a rare skull infection saw some improvement with a long antibiotic course, but his condition remained c…
Systematic review finds no difference in hypoglycemia or ketoacidosis between insulin types
Children on insulin may not need newer expensive versions
A meta-analysis of 1,107 children with type 1 diabetes found no significant difference in severe hypoglycemia, ketoacidosis, or serious adve…
A major review finds older human insulin works as safely as newer analogues for children with type 1 diabetes, which could ease costs for fa…
Semaglutide reduces insulin dose in adults with type 1 diabetes and obesity
Semaglutide Cuts Insulin Needs By Half In Type 1 Diabetes
A post hoc analysis of an RCT found that semaglutide 1 mg/week significantly reduced total daily insulin dose by 22.6% over 26 weeks in adul…
Semaglutide reduces insulin needs quickly in type 1 diabetes patients, offering a new hope for better blood sugar control and weight managem…
Umbrella review identifies risk factors and protective factors for male infertility and semen quality
New study lists many things that hurt male fertility and health
This umbrella review of 43 studies synthesizes evidence on risk factors for male infertility and abnormal semen parameters.
A new review shows that obesity, smoking, and certain illnesses can hurt sperm, but healthy habits might fix the problem.
Narrative review of transposable element methylation in autoimmune diseases
Genetic elements may link autoimmune diseases to inflammation
This narrative review examines the role of transposable element (TE) methylation and expression in Type 1 diabetes, systemic lupus erythemat…
Changes in certain genetic elements could explain how the body triggers inflammation in diseases like lupus and rheumatoid arthritis.
Questions about Type 1 diabetes mellitus
Can cervical cancer treatment cause new Type 1 diabetes and diabetic ketoacidosis?
Yes, certain cervical cancer treatments, especially immune checkpoint inhibitors like cadonilimab, can trigger new-onset type 1 diabetes and diabetic ketoacidosis, though this is a rare but serious side effect.
Full answer →Can integrative therapies help improve blood sugar control in Type 1 diabetes?
Integrative therapies like yoga and naturopathy may offer modest adjunctive benefits for blood sugar control in Type 1 diabetes, but evidence is limited and they should complement, not replace, standard insulin therapy.
Full answer →