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Home › Medications › dexamethasone

dexamethasone

28 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of dexamethasone

448 trials tracked of dexamethasone: 163 in phase 3 or 4 and 67 with published results. The most-cited published study has 1325 citations.

448Trials tracked
163Phase 3 & 4
0Recruiting
67With published results
Phase distribution
Phase 4 51 Phase 3 112 Phase 2 232 Phase 1 22 Other / NA 31
  1. Phase 3 Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Relapsed or Refractory Multiple Myeloma Completed · 1,325 cited
  2. Phase 3 Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma. Completed · 423 cited
  3. Phase 3 A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy Completed · 407 cited
  4. Phase 3 Safety and Efficacy of Pomalidomide, Bortezomib and Low-dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma Completed · 385 cited
  5. Phase 3 Multinational Clinical Study Comparing Isatuximab, Carfilzomib And Dexamethasone To Carfilzomib And Dexamethasone In Relapse And/Or Refractory Multiple Myeloma Patients Completed · 381 cited
  6. Phase 3 Comparison of Pom and Dex in Subjects With RRMM Previously Treated With Len and a PI Dara/Pom/Dex vs Pom/Dex Completed · 327 cited
Show 44 more trials
  1. Phase 3 Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL) Completed · 325 cited
  2. Phase 3 Stem Cell Transplantation in Individuals With Multiple Myeloma (BMT CTN 0102) Completed · 277 cited
  3. Phase 3 Aprepitant ,Olanzapine,Palonosetron and Dexamethasone for the Prevention of Chemotherapy-induced Nausea and Vomiting Completed · 251 cited
  4. Phase 3 Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed · 251 cited
  5. Phase 3 05-001: Treatment of Acute Lymphoblastic Leukemia in Children Completed · 241 cited
  6. Phase 3 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed · 231 cited
  7. Phase 3 PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial Completed · 212 cited
  8. Phase 3 Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma Completed · 207 cited
  9. Phase 3 Dexamethasone vs Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy for Bone Metastases Completed · 171 cited
  10. Phase 3 Evaluation of Safety of Pomalidomide in Combination With Dexamethasone (Low Dose) in Patients With Refractory or Relapsed and Refractory Multiple Myeloma Completed · 162 cited
  11. Phase 3 Adaptive COVID-19 Treatment Trial 4 (ACTT-4) Completed · 152 cited
  12. Phase 3 A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma Completed · 141 cited
  13. Phase 4 Adductor Canal Block With Periarticular Injection and IPACK (ACB/PAI/IPACK) Versus Periarticular Injection (PAI) Completed · 133 cited
  14. Phase 3 A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Completed · 130 cited
  15. Phase 3 Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE) Completed · 123 cited
  16. Phase 3 Addition of Daratumumab to Combination of Bortezomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma Completed · 120 cited
  17. Phase 3 A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy Completed · 114 cited
  18. Phase 3 Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Completed · 102 cited
  19. Phase 3 IXAZOMIB Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma Completed · 99 cited
  20. Phase 4 Tumor Gene Expression in Women With Ovarian Cancer Completed · 91 cited
  21. Phase 3 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Completed · 86 cited
  22. Phase 4 Single Injection Adductor Canal Block vs Catheter for Total Knee Arthroplasty Completed · 75 cited
  23. Phase 4 Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery Completed · 65 cited
  24. Phase 3 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Completed · 59 cited
  25. Phase 3 Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921) Completed · 49 cited
  26. Phase 3 Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Completed · 48 cited
  27. Phase 3 Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed · 47 cited
  28. Phase 3 Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma Completed · 47 cited
  29. Phase 4 Dexamethasone Intravitreal Implant for the Treatment of Persistent Diabetic Macular Edema Completed · 45 cited
  30. Phase 3 Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Participants With Previously Untreated Multiple Myeloma Completed · 45 cited
  31. Phase 4 Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19 Completed · 43 cited
  32. Phase 3 A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Completed · 43 cited
  33. Phase 3 A Safety Study of Intravenous Pro-Netupitant and Palonosetron Combination for the Prevention of Nausea and Vomiting Completed · 40 cited
  34. Phase 4 Dexamethasone for Post-cesarean Delivery Pain Completed · 37 cited
  35. Phase 3 Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed · 37 cited
  36. Phase 3 Corticosteroids for Children With Febrile Urinary Tract Infections Completed · 33 cited
  37. Phase 3 A Study Of IV Casopitant For The Prevention Of Chemotherapy Induced Nausea And Vomiting. Completed · 32 cited
  38. Phase 3 Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease Completed · 32 cited
  39. Phase 3 Bortezomib, Selinexor, and Dexamethasone in Patients With Multiple Myeloma Completed · 31 cited
  40. Phase 3 Multinational Clinical Study Comparing Isatuximab, Pomalidomide, and Dexamethasone to Pomalidomide and Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma Patients Completed · 31 cited
  41. Phase 3 A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC Completed · 24 cited
  42. Phase 4 Preoperative High Dose Steroids for Liver Resection- Effect on Complications in the Immediate Postoperative Period Completed · 22 cited
  43. Phase 3 Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial Completed · 22 cited
  44. Phase 4 Corticosteroids for Acute Migraine in the Emergency Department Completed · 20 cited

Showing the 50 most-cited and recently-updated of 448 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Real-world study shows lenalidomide-dexamethasone yields 22.9-month PFS in transplant-ineligible myeloma
Oncology Phase III
Real-world study shows lenalidomide-dexamethasone yields 22.9-month PFS in transplant-ineligible myeloma Real-world study shows lenalidomide treatment outcomes for older multiple myeloma patients
A prospective, non-interventional study of 168 transplant-ineligible NDMM patients in Germany found median PFS of 22.9 months and OS of 58.1…
Real-world data shows lenalidomide plus low-dose dexamethasone keeps older multiple myeloma patients disease-free for nearly two years while…
Apr 3, 2026
Antenatal dexamethasone reduces respiratory support need in late preterm infants in Vietnamese RCT
Pulmonology & Critical Care RCT
Antenatal dexamethasone reduces respiratory support need in late preterm infants in Vietnamese RCT Can a steroid shot before late preterm birth help babies breathe easier?
A randomized controlled trial of 294 pregnant women at risk of late preterm delivery in Vietnam found antenatal dexamethasone reduced infant…
Giving mothers a steroid shot before late preterm birth cut the need for breathing support in babies by nearly 10%, reducing hospital stays …
Apr 2, 2026
Perineural dexamethasone extends analgesia duration in upper limb surgery blocks versus bupivacaine alone
Anesthesiology & Pain Medicine RCT
Perineural dexamethasone extends analgesia duration in upper limb surgery blocks versus bupivacaine alone Can a common steroid make pain relief from arm surgery last longer?
A double-blinded RCT in 90 ASA I/II patients undergoing upper limb procedures found adding 4 mg perineural dexamethasone to bupivacaine sign…
Adding a tiny amount of common steroid dexamethasone to arm surgery numbing shots nearly doubled pain relief time to over 20 hours with few …
Apr 2, 2026
Daratumumab + Len/Dex shows ORR in relapsed/refractory multiple myeloma phase 1/2 trial
Hematology Phase II
Daratumumab + Len/Dex shows ORR in relapsed/refractory multiple myeloma phase 1/2 trial Can a new drug combination help people with multiple myeloma that has returned after treatment?
This phase 1/2 study evaluated daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed-refracto…
A new three-drug combination of daratumumab, lenalidomide, and dexamasone showed safety and response in people with relapsed multiple myelom…
CT.gov Mar 30, 2026