HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Anesthesiology & Pain Medicine
Cohort
In a cohort of 561 individuals with chronic pain, sex and gender identity influenced repeated prescription refill odds.
Your Pain Meds May Depend on Who You Are, Not Just What Hurts
This observational cohort study examined 561 individuals living with chronic pain using public and private prescription claims data over one…
Chronic pain treatment isn’t one-size-fits-all; new research shows your personal identity plays a major role in the prescriptions you receiv…
Frontiers
Apr 22, 2026
Psychiatry
Chronic pain linked to 7.5-fold increase in severe depressive symptoms in UK Biobank analysis
Does chronic pain make depression worse? New data says yes, and the link goes both ways.
An observational study of 142,688 UK Biobank participants found chronic pain associated with a 7.50-fold increase in severe depressive sympt…
Chronic pain makes depression worse and depression increases pain risk, creating a two-way link that affects mood, focus, and appetite.
medRxiv
Apr 14, 2026
Anesthesiology & Pain Medicine
RCT
Mobile app engagement and perceived usefulness in adult primary care patients with chronic pain
The Pain App Most People Kept Opening
This feasibility randomized controlled trial conducted a secondary analysis of data from 49 adult primary care patients with chronic pain. T…
A mobile app for chronic pain held people's attention for weeks on average, though deeper engagement varied widely from one user to the next…
Apr 13, 2026
Psychiatry
Cross-sectional study finds brain structure alterations in chronic pain and depression
Pain and Sadness Share a Unique Brain Map
A cross-sectional observational study of 71,214 UK Biobank participants found widespread brain structure alterations in individuals with com…
Millions with chronic pain and depression have a unique brain map that differs from having just one condition, changing how doctors should t…
medRxiv
Apr 12, 2026
Cardiology
Cohort
Percutaneous auricular VNS linked to blood pressure reduction in hypertensive chronic pain patients
Could Clipping a Device to Your Ear Lower Blood Pressure?
A retrospective dual-center cohort study of 24 chronic pain patients found percutaneous auricular vagus nerve stimulation (aVNS) was associa…
Gentle electrical pulses to the ear significantly lowered blood pressure in untreated patients with high blood pressure over eight weeks.
Frontiers
Apr 10, 2026
Anesthesiology & Pain Medicine
RCT
Pilot RCT finds mindfulness intervention feasible for chronic pain in cancer survivors
Can mindfulness help cancer survivors manage chronic pain? A small study explores.
A pilot randomized controlled trial of 60 cancer survivors with moderate-to-severe chronic pain tested three formats of Mindfulness-Oriented…
Cancer survivors with chronic pain reported less bothersome and severe pain after a short mindfulness program, though the study was too smal…
Apr 7, 2026
OB/GYN & Women's Health
Cohort
Retrospective study finds higher sexual problem rates in females with hEDS versus chronic pain controls
Do hypermobile EDS and HSD affect sexual health? A new study finds a link.
A retrospective cohort study of 1407 patients found females with hypermobile Ehlers–Danlos syndrome (hEDS) reported significantly higher rat…
Women with hypermobile EDS report higher rates of sexual problems like pain during sex and difficulty reaching orgasm, a study of over 1,400…
Frontiers
Apr 5, 2026
Infectious Disease
Observational report describes high chronic pain prevalence among U.S. adults
Report describes high chronic pain levels among U.S. adults
An observational report describes high prevalence of chronic pain among U.S. adults. No specific prevalence rates, statistical measures, or …
A new report describes a high prevalence of chronic pain among U.S. adults, highlighting it as a significant issue that needs more specific …
CDC
Apr 5, 2026
Anesthesiology & Pain Medicine
RCT
Hypnotic cognitive therapy reduces pain intensity in adults with spinal cord injury
Remote hypnosis therapy shows modest pain relief for adults with spinal cord injury
A randomized controlled trial in 127 community-residing adults with spinal cord injury and chronic pain found that 6 weeks of remote hypnoti…
Remote hypnosis therapy offered by phone or video call helped adults with spinal cord injury manage chronic pain and reduced depression symp…
Apr 3, 2026
Anesthesiology & Pain Medicine
Cohort
Antibiotic duration and type associated with chronic post-amputation pain in military cohort
Study finds link between antibiotic use and chronic pain after traumatic amputation
A retrospective cohort study of 212 military personnel with traumatic amputations found prolonged antibiotic use (>21 days) and combined reg…
Using antibiotics for more than 21 days or taking two or more types together increased the risk of chronic pain after traumatic amputation i…
Frontiers
Apr 3, 2026
Anesthesiology & Pain Medicine
Sys. Review
Narrative review describes bidirectional relationship between sarcopenia and pain in older adults
Why do muscle loss and chronic pain feed off each other in older adults?
A narrative review synthesizes evidence on the connection between sarcopenia and pain in aging populations. It describes a bidirectional rel…
Older adults with chronic pain often lose muscle strength, while losing muscle makes pain worse, creating a dangerous cycle fueled by aging …
Frontiers
Apr 3, 2026
Psychiatry
RCT
Secondary analysis identifies possible mediators for chronic pain treatments in Veterans
Study in Veterans with chronic pain explores how three mind-body treatments may work
A secondary analysis of a 3-arm RCT in 328 Veterans with chronic pain found that across clinical hypnosis, mindfulness, and pain education, …
Veterans with chronic pain who tolerated pain better, engaged in valued activities, and worried less about pain found relief across three mi…
Apr 3, 2026