Endovascular therapy reduces post-thrombotic syndrome severity by 2.0 points compared to standard care
Endovascular Therapy Improves Quality of Life for Post-Thrombotic Syndrome
This randomized controlled trial of 225 patients with moderate or severe post-thrombotic syndrome and iliac-vein obstruction found that endo…
A new trial shows that endovascular therapy can reduce the severity of post-thrombotic syndrome and improve daily quality of life.
Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
Trial shows ziv-aflibercept improves vision in macular edema cases
This systematic review and meta-analysis of 5 RCTs and 8 observational studies found that intravitreal ziv-aflibercept significantly reduced…
A new eye treatment called ziv-aflibercept may help reduce swelling and improve vision for patients with specific types of macular edema.
LMWH remains useful when oral anticoagulants are difficult to use safely in venous thromboembolism patients
Low-molecular-weight heparin remains useful when oral anticoagulants are difficult to use safely
This narrative review examines low-molecular-weight heparin dosing, anti-factor Xa monitoring, treatment interruption, and switching strateg…
A review suggests low-molecular-weight heparin stays useful when oral anticoagulants are difficult to use safely for patients with venous th…
Systematic review and meta-analysis of machine learning models for deep vein thrombosis prediction in hospitalized adults
Machine learning models predict blood clots in hospitalized adults with high accuracy
This systematic review and meta-analysis synthesized evidence on machine learning-based prediction models for deep vein thrombosis in hospit…
A new analysis of 17 studies shows machine learning models can predict deep vein thrombosis in hospitalized patients with an accuracy score …
Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
Vaccination Before Infection Cuts Heart and Stroke Risks in COVID Patients
This systematic review and meta-analysis examined the association between pre-infection COVID-19 vaccination and cardiovascular outcomes in …
Pre-infection COVID-19 vaccination significantly lowers risks of heart attacks, strokes, and other cardiovascular events in infected individ…
Meta-analysis finds modest PTS reduction with compression stockings after DVT
Long-term stockings lower risk of post-thrombotic syndrome in deep vein thrombosis patients
This meta-analysis of 1,775 patients with deep vein thrombosis evaluated long-term graduated compression stockings. It found a modest reduct…
A large review found long-term compression stockings modestly reduce the risk of post-thrombotic syndrome in people with deep vein thrombosi…
Postoperative VTE prediction models show substantial heterogeneity and high bias risk in lung cancer surgery patients undergoing systematic review analysis
Existing lung cancer VTE prediction models show mixed results in surgery patients
A systematic review of twenty prediction models for venous thromboembolism in lung cancer surgery patients revealed substantial heterogeneit…
A review of twenty studies found that current tools for predicting blood clots in lung cancer surgery patients vary widely in accuracy and c…
Network meta-analysis compares DOACs and VKAs for intracranial hemorrhage risk
Dabigatran may be safest for brain bleeding risk
This network meta-analysis of 127,267 patients with venous thromboembolism or atrial fibrillation found that all DOACs had lower risk of int…
All blood thinners beat warfarin for brain bleed risk, but dabigatran may be the safest choice.
Systematic review and meta-analysis links D-dimer and ultrasound findings to recurrent venous thromboembolism risk
Doctors find high D-dimer levels and ultrasound results predict higher risk of blood clot return
This systematic review and meta-analysis of 48 articles evaluates the association between residual vein thrombosis and positive post-treatme…
A review of many studies shows that leftover blood clots and high D-dimer levels after treatment raise the chance of venous thromboembolism …
Systematic review of Dendrobium phenanthrene bioactivity across multiple disease models
Scientists found many plant chemicals that fight cancer and help diabetes in lab tests
This systematic review evaluates the bioactivity of 158 phenanthrene metabolites isolated from 53 Dendrobium taxa. The authors note that 64 …
A review of plant chemicals from Dendrobium plants shows strong activity against cancer and diabetes in lab studies. Most results come from …
Subprophylactic anti-Xa levels linked to higher venous thromboembolism risk in critically ill adults receiving low-molecular-weight heparin
Low blood clot prevention drug levels linked to higher risk in sick adults
A systematic review and meta-analysis of 7,124 critically ill adults reveals that 47% failed to achieve target anti-Xa levels. Subprophylact…
A large review found that nearly half of critically ill adults did not reach safe drug levels. Those with lower levels faced a much higher c…
FDA Approves Pavblu (aflibercept) for Neovascular AMD, RVO, DME, and DR
FDA approves Pavblu to treat several eye conditions that cause vision loss.
The FDA approved Pavblu (aflibercept) for neovascular AMD, macular edema following RVO, DME, and DR. It is a VEGF inhibitor administered by …
The FDA approved Pavblu (aflibercept) for wet age-related macular degeneration, macular edema, diabetic macular edema, and diabetic retinopa…