Updated PHS guidelines recommend HIV, HBV, and HCV testing for pediatric transplant candidates under 12
U.S. updates guidelines for HIV and hepatitis testing in young transplant candidates
Updated U.S. Public Health Service guidelines recommend testing for HIV, Hepatitis B, and Hepatitis C in transplant candidates under age 12.
U.S. doctors now must test children under 12 for HIV and hepatitis before organ transplants to protect both the patient and the donated orga…
WHO European Region progress toward hepatitis B control assessed from 2016 to 2019
WHO European Region reports on hepatitis B control progress from 2016 to 2019
A WHO report assessed progress toward hepatitis B control in the WHO European Region from 2016 to 2019.
WHO Europe tracked hepatitis B control progress from 2016 to 2019, showing how the region advanced toward public health goals for this viral…
Vaccination efforts target elimination of mother-to-child hepatitis B transmission in the Americas
Can vaccination end hepatitis B passing from mothers to babies in the Americas?
A regional report describes vaccination efforts aimed at eliminating mother-to-child transmission of hepatitis B virus in the Americas.
Health leaders in the Americas are chasing a future where no baby is born with hepatitis B through vaccination efforts to stop mother-to-chi…
HBV RNA positivity at nucleoside analogue discontinuation linked to higher relapse risk in chronic hepatitis B
What happens when hepatitis B patients stop their medication? A key marker may predict relapse
A meta-analysis of 21 cohort studies including 2,043 chronic hepatitis B patients found HBV RNA-positive individuals had 1.9-fold higher vir…
Stopping hepatitis B medication carries higher relapse risk if a specific viral marker called HBV RNA is still detectable in the blood.
Research across Hepatitis
Related studies from across the Hepatitis family.
Epigallocatechin-3-gallate shows positive therapeutic effects on various digestive system diseases in animal models
Green tea compound shows potential for several digestive diseases
This meta-analysis of 63 preclinical studies involving 738 animals indicates that Epigallocatechin-3-gallate (EGCG) has a positive therapeut…
A review of animal studies suggests a green tea compound could help treat various cancers and digestive conditions.
HLA-B*57:01-guided abacavir prescribing is the clearest preventive paradigm from HLA associations
HLA genes shape HIV and hepatitis vaccine responses and drug reactions
This narrative review examines HLA polymorphisms in HIV, hepatitis C, and hepatitis B. The clearest preventive paradigm is HLA-B*57:01-guide…
A review finds that HLA genes strongly influence how people respond to HIV and hepatitis vaccines and how they react to certain medications.
Chronic HCV infection drives T cell dysfunction, regulatory T cell accumulation, and metabolic defects that persist after viral clearance
Immune defects in hepatitis C may last after the virus is gone
This narrative review examines immune mechanisms in patients with chronic hepatitis C virus infection. The authors describe how prolonged an…
A review explains how chronic hepatitis C causes lasting immune changes that persist even after the virus is cleared, suggesting new treatme…
One in six blood donors in Cameroon carries Plasmodium infection, meta-analysis finds
1 in 6 blood donors in Cameroon carries malaria parasite
A systematic review and meta-analysis of 18 studies (~12,500 donations) found a 16.6% pooled prevalence of Plasmodium spp. in Cameroonian bl…
A review of 18 studies finds 16.6% of blood donations in Cameroon contain Plasmodium, the malaria parasite.
Systematic review and meta-analysis of biopsy-guided versus clinically guided withdrawal in autoimmune hepatitis
Biopsy-guided withdrawal shows no benefit over clinical guidance for autoimmune hepatitis
This systematic review and meta-analysis evaluated relapse rates after treatment withdrawal in patients with autoimmune hepatitis.
A meta-analysis of 518 patients found that biopsy-guided withdrawal did not lower relapse rates compared to clinically guided withdrawal in …
HEV 239 vaccine induces durable humoral and cellular immunity in Bangladeshi women
Hepatitis E vaccine shows durable immunity in women
This longitudinal cohort study in 1480 women aged 16-39 years in Bangladesh found that HEV 239 (Hecolin) vaccination led to significantly hi…
A hepatitis E vaccine kept women protected for up to 3 years, with stronger immune memory than a comparison group.
Hepatic steatosis prevalence and impact in autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis
Fatty liver makes autoimmune hepatitis and PBC worse, but not PSC
This systematic review and meta-analysis of 19,898 patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing c…
A large review found fatty liver is common in autoimmune liver diseases and makes outcomes worse for some patients, but not others.
Narrative review on ICIs in patients with viral infections and solid tumors
Cancer Immunotherapy Works Differently in Viral Infections
This narrative review synthesizes evidence on immune checkpoint inhibitors in patients with viral infections and solid tumors.
Cancer immunotherapy can still work—and sometimes even control viruses like hepatitis or HIV—but doctors must watch for dangerous flare-ups.
Integrative review of Epimedium flavonoids in hepatitis and cirrhosis shows preclinical promise but lacks clinical validation
Ancient Herb Shows New Promise for Liver Scarring and Hepatitis
This integrative review synthesizes data from 33 high-impact studies regarding Epimedium species and its bioactive flavonoids, icariin and i…
This research suggests a traditional herb may offer a new way to protect the liver, but more work is needed to prove it’s safe and effective…
Meta-analysis of 55 studies assesses HCV prevalence trends across Eastern Mediterranean Region populations
HCV Rates Drop in High-Risk Groups After 2015
This umbrella review synthesizes data from 55 meta-analyses evaluating hepatitis C virus (HCV) prevalence in the Eastern Mediterranean Regio…
Imagine walking into a doctor's office and feeling a knot of worry in your stomach.
Randomized trial shows ribavirin increases mutational load and specific transition signatures in HCV
Ribavirin linked to increased hepatitis C virus mutations in trial
This secondary analysis of a randomized trial in HCV-infected participants found ribavirin exposure significantly increased total mutational…
Ribavirin treatment linked to increased hepatitis C virus mutations in a trial, though real-world impact on cure rates remains unclear.
Narrative review synthesizes evidence on NAFLD, NASH, and viral hepatitis management without reported trial data
Your Liver Has an Immune Army — and It Can Turn Against You
This narrative review addresses management considerations for nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH),…
Your liver's own immune cells can turn on itself to cause permanent scarring, but scientists are now mapping these cells to stop the damage …
Questions about Hepatitis B
Can hepatic steatosis make fibrosis staging less accurate in chronic hepatitis B?
Yes, hepatic steatosis can significantly reduce the accuracy of noninvasive fibrosis staging tools like APRI and FIB-4 in chronic hepatitis B patients.
Full answer →What are the side effects of pegylated interferon-alpha for chronic hepatitis B?
Pegylated interferon-alpha for chronic hepatitis B commonly causes flu-like symptoms, bone marrow suppression, depression, and autoimmune reactions, often leading to dose adjustments.
Full answer →Can receiving a liver transplant from a donor with Hepatitis B Virus cause infection?
Yes, a liver transplant from a donor with HBV can transmit the virus, but the risk is low (about 4%) and can be reduced with antiviral drugs and vaccination.
Full answer →Does having Hepatitis B Virus Infection make my liver surgery more likely to fail?
Yes, active HBV infection can increase the risk of liver surgery failure, mainly due to higher chances of viral reactivation and liver damage, but antiviral therapy significantly lowers this risk.
Full answer →Are immune checkpoint inhibitors safe for patients with Hepatitis B Virus Infection and solid tumors?
Immune checkpoint inhibitors appear safe for HBV patients with solid tumors when viral load is suppressed, but reactivation risk exists, especially during immunosuppression for immune-related adverse events.
Full answer →How does Hepatitis B infection prevalence differ among US adults based on their race and origin?
NHANES data show that among US adults, past or present Hepatitis B infection is more common in Black adults and those born outside the US compared to White adults or those born in the US.
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