Meta-analysis of pucotenlimab shows improved outcomes across multiple solid tumors
New analysis shows pucotenlimab improves outcomes for several solid tumor types.
This meta-analysis evaluated pucotenlimab (HX008) in patients with gastric, gastroesophageal junction, triple-negative breast cancer, melano…
A new analysis of pucotenlimab shows significantly improved outcomes versus control for patients with gastric cancer, triple-negative breast…
Narrative review discusses MicroRNAs in melanoma without reported outcomes or safety data
A review explores how MicroRNAs might relate to Melanoma
This narrative review examines the role of MicroRNAs in melanoma. The authors discuss the topic but do not report specific outcomes, safety …
This narrative review discusses MicroRNAs in the context of Melanoma, offering a broad overview of current scientific understanding.
Meta-analysis finds modest melanoma risk increase among infertile women using fertility treatments
Fertility Drugs Linked to Slight Rise in Melanoma Risk
This systematic review and meta-analysis evaluated melanoma incidence in infertile women exposed to fertility treatments compared to untreat…
A large review finds fertility drugs may raise melanoma risk slightly, but the increase is small and more research is needed.
Pathologic features predict rapid recurrence in T1 melanoma patients across 14 sites.
Why Thin Melanomas Kill Older Adults
This observational review analyzed 442 patients with T1 melanoma from 14 sites to identify predictors of rapid recurrence. Significant assoc…
Doctors now know that thin melanomas can be deadly for older adults if they return within two years, requiring closer monitoring than previo…
FDA Approves Keytruda (pembrolizumab) for Treatment of Unresectable or Metastatic Melanoma
FDA approves new drug Keytruda for advanced skin cancer.
The FDA has approved Keytruda, a PD-1-blocking antibody, for the treatment of patients with unresectable or metastatic melanoma. This approv…
FDA approves Keytruda to treat advanced skin cancer that cannot be removed by surgery or has spread to other parts of the body.
Retrospective analysis identifies molecular correlates of benefit with encorafenib-based therapy in BRAF-mutant melanoma
Melanoma study finds tumor genetics and immune markers may predict treatment benefit
A retrospective exploratory analysis of the phase III COLUMBUS trial in 921 patients with BRAF V600E/K-mutant advanced melanoma found that s…
Patients with advanced melanoma who have higher tumor mutational burden or signs of immune system activity gain the most survival benefit fr…
Sentinel Node Biopsy Associated with Reduced Melanoma Mortality and Recurrence in Meta-Analysis
Does checking lymph nodes help people with melanoma live longer?
A systematic review and meta-analysis of 13 studies with 40,287 adults with melanoma found sentinel node biopsy (SNB) was associated with a …
Checking lymph nodes during melanoma diagnosis is linked to a lower risk of dying from the cancer and less chance of it returning.
Systematic review finds neoantigen vaccines show recurrence-free survival benefit in adjuvant melanoma
Can a custom vaccine help stop melanoma from coming back?
A systematic review of clinical trial data found that customised neoantigen vaccines, specifically mRNA-4157 from the KEYNOTE-942 trial, dem…
A custom mRNA vaccine linked to longer recurrence-free survival for melanoma patients after surgery, though it works best against 'hot' tumo…