Retrospective study finds 12.1% of PD/ET patients underwent DBS surgery at a tertiary center
Who gets brain surgery for Parkinson's? Insurance and neighborhood matter
A retrospective cohort study of 3286 PD/ET patients at a single tertiary center found 12.1% underwent DBS surgery.
At one major center, patients with public insurance and low-income neighborhoods were more likely to get advanced brain surgery for Parkinso…
MRgFUS thalamotomy lesion connectivity patterns linked to tremor control in Parkinson's disease
What makes a Parkinson's tremor treatment last? Brain connections may hold the answer
A retrospective observational study of 20 patients with tremor-dominant Parkinson's disease found durable tremor control after unilateral MR…
Parkinson's tremor relief lasts longer when brain lesions connect to movement areas rather than coordination centers, according to a new ana…
Parkinson disease death rates increased in US adults 65+ from 1999 to 2017
Parkinson's disease death rates rose in older U.S. adults from 1999 to 2017
An observational analysis of US national vital statistics found age-adjusted Parkinson disease death rates increased from 41.7 to 65.3 per 1…
Parkinson's disease death rates for older U.S. adults rose from 41.7 to 65.3 per 100,000 people between 1999 and 2017.
Cycling exercise may reduce urinary symptom progression in early Parkinson's disease pilot trial
Could regular cycling help with bladder problems in early Parkinson's?
An exploratory analysis of a pilot RCT in 30 patients with early Parkinson's disease found that 24 weeks of cycling exercise was associated …
Regular cycling may help slow worsening bladder symptoms in early Parkinson's, though this small study needs larger trials to confirm the be…
Telehealth CBT improves quality of life in veterans with Parkinson's disease and comorbid depression
Telehealth therapy improved quality of life for veterans with Parkinson's and depression
In a randomized controlled trial of 90 veterans with Parkinson's disease and primary depressive disorders, telehealth-delivered PD-informed …
Veterans with Parkinson's and depression who used video therapy saw better physical and mental quality of life compared to standard care.
Color therapy shows reduced fatigue and depression, improved quality of life in Parkinson's patients
Color therapy study shows possible benefits for Parkinson's fatigue, mood, and quality of life
A randomized controlled trial of 60 Parkinson's patients found that color therapy with purple, yellow, and orange light exposure significant…
Parkinson's patients who viewed colored lights reported less fatigue and depression, plus better quality of life, compared to those receivin…
GLP-1RAs Show No Significant Motor Benefit in Parkinson's Disease Meta-Analysis
GLP-1 drugs show no clear motor benefit for Parkinson's in analysis of 708 patients
A meta-analysis of 5 RCTs involving 708 patients with Parkinson's disease found no statistically significant benefit of GLP-1 receptor agoni…
A new analysis of 708 Parkinson's patients found that diabetes drugs called GLP-1s offered no clear benefit for movement symptoms and caused…
Review organizes pharmacological strategies targeting gut-brain axis for neurological and psychiatric disorders
Could targeting gut health help treat brain disorders?
A systematic review summarizes mechanisms of microbiota–gut–brain axis dysfunction and organizes existing pharmacological strategies for con…
Treating brain disorders like Parkinson's and depression may involve targeting the gut-brain connection to reduce shared inflammation.
Fatal serotonin syndrome in Parkinson's patient on rasagiline after sequential SSRI administration
Case report describes fatal serotonin syndrome in older Parkinson's patient on multiple medications
A case report describes a 72-year-old Parkinson's patient on rasagiline who developed fatal serotonin syndrome after sequential sertraline a…
A 72-year-old Parkinson's patient died after taking two antidepressants with a genetic makeup that slowed drug processing, causing fatal ser…