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Home › Conditions › Nicotine Use Disorder

Nicotine Use Disorder

Part of Tobacco Dependence

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Nicotine Use Disorder

9 trials tracked for Nicotine Use Disorder.

9Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 1 Phase 1 2 Other / NA 6
  1. Phase 2 Combined Pharmaco/Behavior Therapy in Adolescent Smokers Completed
  2. Phase 1 Effects of E-Cigarette Flavors on Adults TCORS 2.0 Completed
  3. Phase 1 Effects of E-cigarette Flavors on Youth TCORS 2.0 Completed
  4. N/A Neural Basis of Eating Behavior in Abstinent Smokers Completed
  5. N/A Behavioral Memory Modulation in Nicotine Addiction Completed
  6. N/A Neurobiology of Alcohol and Nicotine Co-Addiction Completed
Show 3 more trials
  1. N/A A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults Completed
  2. N/A Families With Substance Use and Psychosis: A Pilot Study Completed
  3. N/A Helping Poor Smokers Quit Completed

Showing the 9 most-cited and recently-updated of 9 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Nicotinic partial agonists show no effect on opioid use in HIV-positive smokers
Infectious Disease RCT
Nicotinic partial agonists show no effect on opioid use in HIV-positive smokers New data on nicotine treatment for HIV patients who use opioids
This secondary analysis of a randomized trial in 97 HIV-positive smokers with risky alcohol use and baseline opioid use found no significant…
A new look at nicotine treatment for HIV patients who use opioids found no difference in opioid use between two drug groups.
May 1, 2026
Observational study examines smoking cessation advice from health professionals to US adults
Infectious Disease
Observational study examines smoking cessation advice from health professionals to US adults How many smokers get told to quit by their doctor?
An observational study assessed the percentage of current cigarette smokers aged ≥18 years in the United States who received advice from a h…
A new study looked at how often doctors and nurses tell their patients who smoke that they should quit.
CDC Apr 4, 2026

Research across Tobacco Dependence

Related studies from across the Tobacco Dependence family.

Report describes U.S. adults' intent and methods for smoking cessation
Infectious Disease
Report describes U.S. adults' intent and methods for smoking cessation Report examines how U.S. adults plan to quit smoking, but findings are not yet available
An observational report describes smoking cessation intentions and methods among U.S.
A new report looks at how U.S. adults plan to quit smoking, but the specific findings have not been released yet.
CDC Apr 4, 2026