Narrative review links microgravity exposure to altered fat distribution and inflammation in metabolic disease models.
How Space Travel Is Unlocking New Ways to Fight Obesity and Diabetes
This narrative review synthesizes evidence from human studies, animal models, and in vitro experiments regarding microgravity and metabolic …
This research shows that the same health problems astronauts face in space are happening to people on Earth who sit too much, and it may lea…
MCH1 Receptor Antagonist RGH-706 Shows Weight Loss in Preclinical and Early Clinical Study
New Drug Targets Hunger Brain Signals to Help Shed Pounds
A preclinical and phase I/II study evaluated the MCH1 receptor antagonist RGH-706 for obesity and Prader-Willi Syndrome. In diet-induced obe…
Scientists found a new medicine that may help people lose weight by turning off hunger signals.
GZR18 showed weight loss in Chinese adults with overweight or obesity in a phase 1b/2a trial.
New Drug Cuts Weight by Nearly 20% in Just 35 Weeks
In this randomized, placebo-controlled phase 1b/2a trial, 60 Chinese adults with overweight or obesity received GZR18 or placebo. Over 26 to…
This new treatment shows huge promise for helping people reach their weight goals without daily pills.
Narrative review on dyslipidemia and erectile dysfunction pathophysiology
High Cholesterol May Damage Sexual Function Directly
This narrative review synthesizes evidence on dyslipidemia and erectile dysfunction. It concludes dyslipidemia contributes to ED through vas…
High blood fats may directly harm sexual function beyond just heart risks.
Randomized trial finds konjac glucomannan reduces weight and cardiometabolic markers in excess weight adults.
Fiber Supplement Slashes Belly Fat and Heart Risk
This randomized controlled trial in 40 adults with excess weight evaluated konjac glucomannan 3 g/day for 12 weeks with diet and activity. T…
This simple fiber could be a powerful ally in lowering heart disease risk for people carrying extra weight.
Tirzepatide MTD Demonstrates Cost-Effectiveness Versus Semaglutide MTD in Obesity Simulation Modeling Study
Tirzepatide Saves Money and Health Over Semaglutide
This simulation modeling study using Phase-3 trial data evaluated tirzepatide versus semaglutide in individuals with obesity or overweight w…
Imagine standing in a doctor's office, facing a choice between two powerful weight-loss medicines.
Narrative review compares tirzepatide and semaglutide for obesity and type 2 diabetes outcomes.
New Obesity Drug Shows Stronger Weight Loss Than Popular Option
This narrative review evaluates tirzepatide versus semaglutide in individuals with obesity or type 2 diabetes mellitus. The authors synthesi…
This review shows that tirzepatide outperforms semaglutide for weight and blood sugar, but semaglutide currently has stronger proof for prot…
Systematic review of antioxidant and anti-inflammatory strategies for male infertility and immune-mediated testicular disorders
Sperm Health Tied to Immune System in New Way
This systematic review synthesizes evidence on targeted antioxidant and anti-inflammatory interventions for male infertility and related imm…
John and Maria tried for years to have a baby.
Narrative review covers IBD, bile acid malabsorption, IBS-D, CRC, obesity, NAFLD, and sepsis-related intestinal injury.
This narrative review discusses bile acid malabsorption and related digestive conditions.
This narrative review examines a broad spectrum of gastrointestinal conditions, including inflammatory bowel disease, bile acid malabsorptio…
Bile acids act as powerful signaling molecules that control gut health, metabolism, and immune responses through a complex network of recept…
IGFBP2 as a context-dependent regulator of metabolic dysregulation in obesity and type 2 diabetes
IGFBP2 may signal metabolic changes in obesity and diabetes, but human proof is still missing.
This review examines IGFBP2 as a potential translational indicator of metabolic dysregulation in conditions including obesity, insulin resis…
A protein called IGFBP2 might signal metabolic changes in obesity and diabetes, but human proof is still missing.
Protocol for coarse-cereal substitution in school meals to prevent obesity in Chinese primary students
Swapping White Rice for Ancient Grains Could Protect Kids From Obesity
This study protocol describes a cluster-randomized pragmatic controlled trial (pRCT) involving 400 Chinese primary school students (grades 3…
Swapping white rice for coarse grains in school lunches is being tested to stop childhood obesity rates from tripling in China.
Narrative review explores links between antibiotic exposure and obesity or metabolic phenotypes
Your Gut Bacteria Remember Every Antibiotic You've Ever Taken
This narrative review examines potential associations between antibiotic exposure and obesity or metabolic phenotypes. The authors discuss v…
Antibiotics may alter your gut bacteria for months or years, potentially raising obesity risk, especially if taken early in life.