Narrative review discusses calcium-modifying balloons for PCI in calcified coronary disease
Review of calcium-modifying balloons for treating calcified coronary artery disease
This narrative review evaluates the role of calcium-modifying dedicated balloons, including scoring, cutting, and ultra-high-pressure device…
Specialized balloons can effectively treat hardened heart arteries, offering versatile options as first-line or complementary tools during p…
Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Metabolic syndrome and TyG index associated with higher in-stent restenosis risk after PCI
Your Stent May Be at Risk from This Hidden Health Cluster
A retrospective cohort study of 565 patients who underwent PCI found metabolic syndrome and the triglyceride-glucose index were independent …
A common cluster of high blood sugar, high triglycerides, and high blood pressure doubles the risk of a heart stent getting clogged again.
Intravascular imaging and FFR-guided PCI reduce major adverse cardiovascular events versus angiography
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
A network meta-analysis of 43 RCTs involving 39,291 patients undergoing PCI found intravascular imaging (IVUS, OCT/OCTA) and fractional flow…
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
LLM ensemble shows potential for PCI decision support in retrospective analysis of 93 patients
AI models show promise for heart procedure decisions but need more testing
A retrospective cohort study of 93 patients from Ruijin Hospital evaluated 15 large language model versions for PCI decision support.
Combining multiple AI models improved heart procedure advice, but performance gaps appeared at specific ages like 73, 75, and 76.
Higher vs lower heparin dosing for elective PCI tested in cluster randomized trial design
Trial will compare two heparin doses for elective heart procedures
A cluster randomized crossover trial design paper outlines a study comparing higher-dose (100 units/kg) versus lower-dose (70 units/kg) unfr…
A new trial will test if a lower dose of heparin works as well as the standard amount for patients having elective heart procedures in Ontar…
Early Aspirin Withdrawal Post-PCI Reduces Bleeding, No MI Increase with P2Y12 Monotherapy
Could Stopping Aspirin Early Help Heart Patients Avoid Bleeding Risks?
Meta-analysis shows early aspirin withdrawal (≤3 months) post-PCI with ticagrelor/prasugrel reduces bleeding (HR=0.55, 95% CI [0.42, 0.71]; …
Stopping aspirin within three months after a heart procedure reduces bleeding risk without increasing heart attack chances for many patients…
Research across Coronary Artery Disease
Related studies from across the Coronary Artery Disease family.
Impact of Routine Functional Testing on Clinical Outcomes in Patients with Coronary Artery Disease
Routine Stress Testing Does Not Reduce Heart Risk After Procedure
Routine functional testing at one year post-PCI did not improve clinical outcomes but led to a higher rate of invasive procedures.
Routine stress testing after heart procedures did not lower the risk of death or heart attacks, but it did lead to more invasive medical pro…
Higher Triglyceride-glucose index increases MACE risk in patients undergoing coronary artery bypass grafting
Higher Triglyceride-Glucose Index Linked to Risks After Heart Surgery
This meta-analysis of 5,978 patients found that a higher Triglyceride-glucose index (TyG) is associated with a 62.4% higher hazard of MACE p…
A higher triglyceride-glucose index is linked to a higher risk of major heart events and death in patients following heart bypass surgery.
Acupuncture improves cardiac function and reduces MACE risk in patients after percutaneous coronary intervention
Acupuncture shows promise for heart function after coronary procedures
This meta-analysis of 759 patients suggests acupuncture may improve cardiac function and reduce major adverse cardiovascular events followin…
Acupuncture may improve heart function and walking distance for patients recovering from procedures to treat coronary artery disease.
Bayesian analysis of P2Y12 inhibitors identifies clinical uncertainties and equivalence in acute coronary syndromes
Trial Shows Prasugrel May Offer Benefits Over Clopidogrel for Heart Patients
This meta-analysis of 60,619 patients following percutaneous coronary intervention evaluates P2Y12 inhibitors using a Bayesian framework. Th…
A large analysis of over 60,000 patients suggests prasugrel may be more effective than clopidogrel for preventing major heart events after p…
Near-Styloid puncture improves first-attempt success and reduces access-site complications in coronary angiography
Near-Styloid Puncture May Improve Success in Heart Procedures
This randomized controlled trial of 380 patients undergoing coronary angiography found that near-styloid puncture significantly improved fir…
A new puncture location for heart procedures may improve success rates and reduce complications like bruising or artery blockage.
Clopidogrel monotherapy reduces bleeding risk to 2.1% versus 3.2% in patients with acute coronary syndromes
Trial shows clopidogrel alone reduces bleeding risk after heart procedures
This prespecified subgroup analysis of a randomized controlled trial involving 7758 patients with acute coronary syndromes found that clopid…
Patients with heart conditions may face fewer bleeding risks by switching to clopidogrel alone after a period of dual therapy.
Sirolimus-Eluting Balloon with Provisional Stenting for Small to Medium Coronary Arteries
Trial shows sirolimus-eluting balloon is comparable to standard stents
A randomized trial demonstrates that sirolimus-eluting balloon treatment is noninferior to systematic DES for target vessel failure in speci…
A new trial shows that a sirolimus-eluting balloon is as effective as standard stents for treating specific coronary artery blockages.
Evaluating Stepwise Dual Antiplatelet Therapy De-escalation in Patients Following Drug-Coated Balloon Angioplasty
Trial Shows Stepwise DAPT De-escalation for Coronary Heart Disease
A prespecified subgroup analysis of the REC-CAGEFREE II trial evaluates the safety of DAPT de-escalation in ACS patients undergoing DCB-only…
New data shows that switching to a simpler blood thinner regimen may be as safe as standard treatment for patients with coronary artery dise…
Impact of Percutaneous Coronary Intervention Complexity on Ticagrelor or Prasugrel Monotherapy Efficacy
Complex heart procedures do not change risks of certain medications
A post hoc analysis of the NEO-MINDSET trial evaluates if PCI complexity influences the safety and efficacy of potent P2Y inhibitor monother…
New analysis shows that complex heart procedures do not change the safety or effectiveness of specific blood-thinning medications.
Impact of Early Aspirin Withdrawal on Myocardial Infarction in Patients After PCI
Aspirin withdrawal shortly after heart procedures may increase heart attack risk
Early aspirin withdrawal within 30 days post-PCI significantly increases myocardial infarction risk, despite long-term reductions in bleedin…
Stopping aspirin within 30 days of a heart procedure may increase the risk of a heart attack in the first month.
Speckle-tracking echo detects coronary artery disease with 77% sensitivity and 75% specificity
Echocardiography Shows Moderate Accuracy for Detecting Coronary Artery Disease
This meta-analysis of 40 non-randomized studies (5,296 participants) found that speckle-tracking echocardiography (STE) has moderate diagnos…
A review of 40 studies shows that speckle-tracking echocardiography can help identify coronary artery disease with moderate accuracy.
Noninferiority of Ultra-thin Biodegradable Polymer Sirolimus Eluting Stents in Diabetic Patients
New stent type shows promise for patients with diabetes and heart disease
A multicenter trial confirms that ultra-thin biodegradable polymer sirolimus-eluting stents meet noninferiority goals compared to durable po…
A new ultra-thin stent may offer a reliable option for people with both diabetes and complex heart disease.
Questions about Percutaneous Coronary Intervention
Can an AI model help doctors decide on my treatment plan for Percutaneous Coronary Intervention?
AI models are not yet proven to help doctors decide on PCI treatment plans; current research focuses on imaging and risk scores, not AI decision support.
Full answer →Does a higher dose of heparin during elective PCI reduce bleeding complications?
Current evidence does not show that a higher heparin dose reduces bleeding; lower doses may be safer, but definitive results from the HD-PCI trial are pending.
Full answer →Will stopping aspirin early after my Percutaneous Coronary Intervention cause a heart attack?
Stopping aspirin early after PCI may increase heart attack risk if no other antiplatelet is used, but switching to a P2Y12 inhibitor alone within 3 months does not significantly raise MI risk and reduces bleeding.
Full answer →Can using intravascular imaging reduce my risk of major adverse events after PCI?
Yes, using intravascular imaging (IVUS or OCT) to guide PCI significantly reduces the risk of major adverse cardiovascular events compared to angiography alone.
Full answer →Does having metabolic syndrome increase my risk of restenosis after Percutaneous Coronary Intervention?
Current evidence does not show a clear link between metabolic syndrome and higher restenosis risk after PCI, though related factors like insulin resistance may play a role.
Full answer →