Narrative review discusses calcium-modifying balloons for PCI in calcified coronary disease
Review of calcium-modifying balloons for treating calcified coronary artery disease
This narrative review evaluates the role of calcium-modifying dedicated balloons, including scoring, cutting, and ultra-high-pressure device…
Specialized balloons can effectively treat hardened heart arteries, offering versatile options as first-line or complementary tools during p…
Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Metabolic syndrome and TyG index associated with higher in-stent restenosis risk after PCI
Your Stent May Be at Risk from This Hidden Health Cluster
A retrospective cohort study of 565 patients who underwent PCI found metabolic syndrome and the triglyceride-glucose index were independent …
A common cluster of high blood sugar, high triglycerides, and high blood pressure doubles the risk of a heart stent getting clogged again.
Intravascular imaging and FFR-guided PCI reduce major adverse cardiovascular events versus angiography
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
A network meta-analysis of 43 RCTs involving 39,291 patients undergoing PCI found intravascular imaging (IVUS, OCT/OCTA) and fractional flow…
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
LLM ensemble shows potential for PCI decision support in retrospective analysis of 93 patients
AI models show promise for heart procedure decisions but need more testing
A retrospective cohort study of 93 patients from Ruijin Hospital evaluated 15 large language model versions for PCI decision support.
Combining multiple AI models improved heart procedure advice, but performance gaps appeared at specific ages like 73, 75, and 76.
Higher vs lower heparin dosing for elective PCI tested in cluster randomized trial design
Trial will compare two heparin doses for elective heart procedures
A cluster randomized crossover trial design paper outlines a study comparing higher-dose (100 units/kg) versus lower-dose (70 units/kg) unfr…
A new trial will test if a lower dose of heparin works as well as the standard amount for patients having elective heart procedures in Ontar…
Early Aspirin Withdrawal Post-PCI Reduces Bleeding, No MI Increase with P2Y12 Monotherapy
Could Stopping Aspirin Early Help Heart Patients Avoid Bleeding Risks?
Meta-analysis shows early aspirin withdrawal (≤3 months) post-PCI with ticagrelor/prasugrel reduces bleeding (HR=0.55, 95% CI [0.42, 0.71]; …
Stopping aspirin within three months after a heart procedure reduces bleeding risk without increasing heart attack chances for many patients…
Research across Coronary Artery Disease
Related studies from across the Coronary Artery Disease family.
Novel pharmacotherapies like resmetirom and GLP-1 receptor agonists offer potential concurrent hepatic and cardiovascular benefits
New Medications Show Potential to Treat Liver and Heart Disease
This systematic review examines the epidemiological links and shared pathophysiological mechanisms between metabolic dysfunction-associated …
Newer drugs like resmetirom and GLP-1 receptor agonists may offer dual benefits for patients with both liver and heart conditions.
Staged PCI reduces severe kidney injury risk after TAVR in aortic stenosis and CAD
Staged heart procedures may lower risk of severe kidney injury
This meta-analysis of 7,119 patients with aortic stenosis and coronary artery disease undergoing TAVR found that staged PCI did not signific…
A new look at heart surgery data suggests that spacing out certain procedures could protect kidneys from severe damage.
SK-121 digital health program improves disease knowledge and medication adherence after PCI
Digital health program improves knowledge and blood pressure for heart patients
This single-centre RCT of 200 patients found that the SK-121 multimodal digital health program did not significantly reduce the SMART2 risk …
A digital health program helped heart patients improve their medical knowledge, medication habits, and blood pressure after a procedure.
Extended DAPT with clopidogrel and aspirin reduces cardiovascular death, myocardial infarction, and stroke risk
Extended dual antiplatelet therapy lowers risks for heart disease patients
This randomized trial of 8250 patients with multivessel coronary artery disease found that extending dual antiplatelet therapy (DAPT) for an…
Patients with coronary artery disease may have lower risks of stroke and heart attack when taking two blood thinners for an extra year.
Comparative Efficacy and Safety of Drug Coated Balloons Versus Drug Eluting Stents
Drug-coated balloons show lower bleeding rates than stents
A meta-analysis reveals that drug-coated balloons offer comparable clinical outcomes to drug-eluting stents while significantly reducing maj…
A large review of heart procedures shows drug-coated balloons offer a viable alternative to stents with fewer major bleeding risks for patie…
Postoperative educational interventions significantly reduce anxiety and depression in patients following coronary artery bypass grafting
Educational programs help patients after heart bypass surgery
This meta-analysis of 1,669 patients found that postoperative educational interventions significantly reduced anxiety (SMD = -0.48) and depr…
New research shows that educational programs can lower anxiety and depression for patients recovering from coronary artery bypass grafting.
21% hypertension prevalence in transgender adults: meta-analysis of cardiovascular morbidities
Transgender adults face high rates of heart disease
This meta-analysis of observational studies reports pooled prevalence of major cardiovascular morbidities among transgender adults aged ≥18 …
One in five transgender adults has high blood pressure, and many have heart disease, a new analysis finds.
Intravascular lithotripsy reduces mortality risk and MACE in calcified coronary lesions compared to rotational atherectomy
Intravascular lithotripsy shows better safety for calcified heart lesions
This meta-analysis of 1247 patients with calcified coronary lesions found that intravascular lithotripsy (IVL) significantly reduced mortali…
A new analysis suggests that using sound waves to break up hard calcium in arteries may lower risks like stroke and heart attack.
Patients with cardiovascular diseases show measurable prevalence of active cancer across multiple conditions
Heart disease patients show measurable risk of developing various cancers
This systematic review and meta-analysis analyzed 4,759,695 patients to determine the prevalence of active cancer in individuals with variou…
New data shows that people with heart conditions like stroke or heart failure have a measurable rate of active cancer cases.
Genetic Polymorphisms of SIRT1 Gene and Susceptibility to Coronary Artery Disease
Specific SIRT1 Gene Variations Linked to Coronary Artery Disease Risk
Meta-analysis identifies specific SIRT1 gene polymorphisms associated with increased coronary artery disease risk under distinct genetic mod…
New research identifies specific SIRT1 gene variations that may increase the risk of developing coronary artery disease.
Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
Better health literacy helps people manage chronic diseases more effectively
This meta-analysis of 138 studies found a moderate positive association (r = 0.29, 95% CI: 0.26-0.31) between health literacy and self-care …
Understanding medical information and using digital tools can help people with chronic conditions like diabetes or heart failure manage thei…
In-hospital mortality rates for coronary artery disease patients following PCI remain within international benchmarks
PCI mortality rates in Asia-Pacific region within international benchmarks
This meta-analysis of 27 studies across 16 registries in the Asia-Pacific region reports in-hospital mortality rates between 0.26% and 2.80%…
A large meta-analysis finds in-hospital death rates after PCI in Asia-Pacific range from 0.26% to 2.80%, with most around 0.9-1.6%.
Questions about Percutaneous Coronary Intervention
Can an AI model help doctors decide on my treatment plan for Percutaneous Coronary Intervention?
AI models are not yet proven to help doctors decide on PCI treatment plans; current research focuses on imaging and risk scores, not AI decision support.
Full answer →Does a higher dose of heparin during elective PCI reduce bleeding complications?
Current evidence does not show that a higher heparin dose reduces bleeding; lower doses may be safer, but definitive results from the HD-PCI trial are pending.
Full answer →Will stopping aspirin early after my Percutaneous Coronary Intervention cause a heart attack?
Stopping aspirin early after PCI may increase heart attack risk if no other antiplatelet is used, but switching to a P2Y12 inhibitor alone within 3 months does not significantly raise MI risk and reduces bleeding.
Full answer →Can using intravascular imaging reduce my risk of major adverse events after PCI?
Yes, using intravascular imaging (IVUS or OCT) to guide PCI significantly reduces the risk of major adverse cardiovascular events compared to angiography alone.
Full answer →Does having metabolic syndrome increase my risk of restenosis after Percutaneous Coronary Intervention?
Current evidence does not show a clear link between metabolic syndrome and higher restenosis risk after PCI, though related factors like insulin resistance may play a role.
Full answer →