Narrative review discusses calcium-modifying balloons for PCI in calcified coronary disease
Review of calcium-modifying balloons for treating calcified coronary artery disease
This narrative review evaluates the role of calcium-modifying dedicated balloons, including scoring, cutting, and ultra-high-pressure device…
Specialized balloons can effectively treat hardened heart arteries, offering versatile options as first-line or complementary tools during p…
Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Metabolic syndrome and TyG index associated with higher in-stent restenosis risk after PCI
Your Stent May Be at Risk from This Hidden Health Cluster
A retrospective cohort study of 565 patients who underwent PCI found metabolic syndrome and the triglyceride-glucose index were independent …
A common cluster of high blood sugar, high triglycerides, and high blood pressure doubles the risk of a heart stent getting clogged again.
Intravascular imaging and FFR-guided PCI reduce major adverse cardiovascular events versus angiography
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
A network meta-analysis of 43 RCTs involving 39,291 patients undergoing PCI found intravascular imaging (IVUS, OCT/OCTA) and fractional flow…
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
LLM ensemble shows potential for PCI decision support in retrospective analysis of 93 patients
AI models show promise for heart procedure decisions but need more testing
A retrospective cohort study of 93 patients from Ruijin Hospital evaluated 15 large language model versions for PCI decision support.
Combining multiple AI models improved heart procedure advice, but performance gaps appeared at specific ages like 73, 75, and 76.
Higher vs lower heparin dosing for elective PCI tested in cluster randomized trial design
Trial will compare two heparin doses for elective heart procedures
A cluster randomized crossover trial design paper outlines a study comparing higher-dose (100 units/kg) versus lower-dose (70 units/kg) unfr…
A new trial will test if a lower dose of heparin works as well as the standard amount for patients having elective heart procedures in Ontar…
Early Aspirin Withdrawal Post-PCI Reduces Bleeding, No MI Increase with P2Y12 Monotherapy
Could Stopping Aspirin Early Help Heart Patients Avoid Bleeding Risks?
Meta-analysis shows early aspirin withdrawal (≤3 months) post-PCI with ticagrelor/prasugrel reduces bleeding (HR=0.55, 95% CI [0.42, 0.71]; …
Stopping aspirin within three months after a heart procedure reduces bleeding risk without increasing heart attack chances for many patients…
Research across Coronary Artery Disease
Related studies from across the Coronary Artery Disease family.
Angiography-derived FFR shows no significant difference in MACE compared to wire-based FFR
Angiography-derived FFR Shows No Difference in Major Heart Events
This meta-analysis of 6,542 patients undergoing coronary revascularization found no significant difference in MACE between angiography-deriv…
A review of 6,542 patients shows that angiography-derived FFR does not change major heart outcomes compared to wire-based FFR.
Antiplatelet monotherapy after ultrashort DAPT shows no statistically significant difference in major bleeding or MACE
Trial Shows Antiplatelet Monotherapy Options for Coronary Artery Disease
This network meta-analysis evaluated antiplatelet monotherapy following an ultrashort course of dual antiplatelet therapy (DAPT) in patients…
New analysis looks at whether switching to a single antiplatelet drug after a short dual therapy period reduces bleeding risks for heart pat…
Sirolimus-coated balloons match paclitaxel-coated balloons for late lumen loss in coronary artery disease
Two Drug-Coated Balloons Go Head-to-Head in Heart Artery Treatment
This meta-analysis compared sirolimus-coated balloons with paclitaxel-coated balloons in patients with coronary artery disease. No significa…
A new analysis compares two drug-coated balloons for heart arteries. One may keep vessels open better, but the difference is small.
mAFP support associated with lower odds of mortality in isolated LM culprit lesion
Heart surgery complexity predicts survival for patients in cardiogenic shock
This RCT substudy of 355 patients with infarct-related cardiogenic shock and multivessel disease found that mAFP support was associated with…
A new analysis shows that the complexity of a patient's heart disease significantly impacts their survival after a heart attack.
Systematic screening for silent myocardial ischemia does not reduce major cardiovascular outcomes in asymptomatic diabetic patients
Screening Diabetics for Hidden Heart Disease Does Not Save Lives
This meta-analysis of randomized trials evaluated the impact of systematic screening for silent myocardial ischemia or occult coronary arter…
Screening people with diabetes for hidden heart disease did not reduce heart attacks, strokes, or deaths, a new analysis finds.
Circulating microRNAs show moderate diagnostic accuracy for coronary artery disease, multi-miRNA panels outperform single markers
Blood markers show promise for spotting heart artery disease
This meta-analysis of 3879 patients with angiography-confirmed coronary artery disease evaluated circulating microRNAs as diagnostic biomark…
A blood test for tiny molecules called microRNAs may help detect coronary artery disease, a new analysis finds.
AI-enhanced CCTA shows 0.823 sensitivity for detecting hemodynamically significant coronary artery disease
AI technology improves accuracy in detecting coronary artery disease
This meta-analysis of approximately 8400 patients with suspected coronary artery disease evaluated AI-enhanced coronary CT angiography (CCTA…
New data shows that artificial intelligence can help doctors more accurately identify significant heart disease using noninvasive imaging te…
Cutting balloon predilatation shows lower acute recoil and stenosis compared to standard balloon
Cutting Balloons May Improve Vessel Opening in Heart Procedures
This randomized trial of 201 patients with de novo coronary lesions found that cutting balloon predilatation resulted in lower acute recoil …
A trial of 201 patients with coronary artery disease shows cutting balloons may lead to less vessel recoil during heart procedures.
80 kV CTCA with DLIR maintains image quality while reducing radiation dose by 54-56%
Lower Voltage CT Scans May Reduce Radiation for Heart Patients
This meta-analysis of 353 patients evaluates low-dose, low-contrast CTCA using 80 kV and 100 kV with iterative or deep learning image recons…
New data suggests using 80 kV instead of 100 kV during heart scans can significantly lower radiation dose while maintaining image quality.
Comparative Outcomes of Robotic Versus Traditional Coronary Artery Bypass Grafting Procedures
Robotic Surgery Shows Similar Outcomes to Traditional Heart Bypass Surgery
A meta-analysis of 27 studies indicates that robotic-assisted techniques provide comparable graft patency and mortality rates compared to tr…
Robotic-assisted heart bypass surgery shows similar survival rates and graft success compared to traditional methods for patients with coron…
T-786C polymorphism of the NOS3 gene is associated with increased risk of acute coronary syndrome
Genetic Variation Linked to Increased Risk of Heart Disease
This meta-analysis of 17,324 subjects found a significant association between the T-786C polymorphism of the nitric oxide synthase 3 (NOS3) …
A specific genetic variation in the NOS3 gene is linked to a higher risk of heart conditions like coronary artery disease and heart attacks.
One-stent technique and OCT-guided DK-crush associated with lower major adverse cardiac events
Trial shows single stent technique may lower heart risks
This post hoc analysis of patients with coronary artery disease evaluated outcomes based on stenting techniques and guidance methods for DK-…
A new analysis of heart procedures suggests that using one stent instead of two may reduce serious complications for patients with complex a…
Questions about Percutaneous Coronary Intervention
Can an AI model help doctors decide on my treatment plan for Percutaneous Coronary Intervention?
AI models are not yet proven to help doctors decide on PCI treatment plans; current research focuses on imaging and risk scores, not AI decision support.
Full answer →Does a higher dose of heparin during elective PCI reduce bleeding complications?
Current evidence does not show that a higher heparin dose reduces bleeding; lower doses may be safer, but definitive results from the HD-PCI trial are pending.
Full answer →Will stopping aspirin early after my Percutaneous Coronary Intervention cause a heart attack?
Stopping aspirin early after PCI may increase heart attack risk if no other antiplatelet is used, but switching to a P2Y12 inhibitor alone within 3 months does not significantly raise MI risk and reduces bleeding.
Full answer →Can using intravascular imaging reduce my risk of major adverse events after PCI?
Yes, using intravascular imaging (IVUS or OCT) to guide PCI significantly reduces the risk of major adverse cardiovascular events compared to angiography alone.
Full answer →Does having metabolic syndrome increase my risk of restenosis after Percutaneous Coronary Intervention?
Current evidence does not show a clear link between metabolic syndrome and higher restenosis risk after PCI, though related factors like insulin resistance may play a role.
Full answer →