Narrative review discusses calcium-modifying balloons for PCI in calcified coronary disease
Review of calcium-modifying balloons for treating calcified coronary artery disease
This narrative review evaluates the role of calcium-modifying dedicated balloons, including scoring, cutting, and ultra-high-pressure device…
Specialized balloons can effectively treat hardened heart arteries, offering versatile options as first-line or complementary tools during p…
Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Metabolic syndrome and TyG index associated with higher in-stent restenosis risk after PCI
Your Stent May Be at Risk from This Hidden Health Cluster
A retrospective cohort study of 565 patients who underwent PCI found metabolic syndrome and the triglyceride-glucose index were independent …
A common cluster of high blood sugar, high triglycerides, and high blood pressure doubles the risk of a heart stent getting clogged again.
Intravascular imaging and FFR-guided PCI reduce major adverse cardiovascular events versus angiography
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
A network meta-analysis of 43 RCTs involving 39,291 patients undergoing PCI found intravascular imaging (IVUS, OCT/OCTA) and fractional flow…
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
LLM ensemble shows potential for PCI decision support in retrospective analysis of 93 patients
AI models show promise for heart procedure decisions but need more testing
A retrospective cohort study of 93 patients from Ruijin Hospital evaluated 15 large language model versions for PCI decision support.
Combining multiple AI models improved heart procedure advice, but performance gaps appeared at specific ages like 73, 75, and 76.
Higher vs lower heparin dosing for elective PCI tested in cluster randomized trial design
Trial will compare two heparin doses for elective heart procedures
A cluster randomized crossover trial design paper outlines a study comparing higher-dose (100 units/kg) versus lower-dose (70 units/kg) unfr…
A new trial will test if a lower dose of heparin works as well as the standard amount for patients having elective heart procedures in Ontar…
Early Aspirin Withdrawal Post-PCI Reduces Bleeding, No MI Increase with P2Y12 Monotherapy
Could Stopping Aspirin Early Help Heart Patients Avoid Bleeding Risks?
Meta-analysis shows early aspirin withdrawal (≤3 months) post-PCI with ticagrelor/prasugrel reduces bleeding (HR=0.55, 95% CI [0.42, 0.71]; …
Stopping aspirin within three months after a heart procedure reduces bleeding risk without increasing heart attack chances for many patients…
Research across Coronary Artery Disease
Related studies from across the Coronary Artery Disease family.
IVUS-guided PCI did not significantly reduce target-vessel failure compared to angiography-guided PCI
Trial shows IVUS guidance does not reduce risk for heart patients
This randomized controlled trial of 2020 patients undergoing complex PCI found that IVUS-guided PCI with stent-optimization criteria resulte…
New data suggests that using special ultrasound imaging during complex heart procedures may not lower the risk of major complications.
Pre-transplant coronary artery disease increases all-cause mortality and post-transplant cardiovascular events in kidney recipients
Pre-existing heart disease increases risks for kidney transplant patients
This meta-analysis of 112,416 kidney transplant recipients found that pre-existing coronary artery disease (CAD) is associated with signific…
Patients with pre-existing coronary artery disease face significantly higher risks of death and graft failure after receiving a kidney trans…
High-intensity interval aerobic exercise improves brachial FMD in coronary artery disease and heart failure
High intensity interval training improves blood flow in heart patients
This network meta-analysis of 6,818 adults with coronary artery disease or chronic heart failure found that high-intensity interval aerobic …
Specific types of intense exercise may improve blood vessel function for people living with heart failure or coronary artery disease.
Higher pan-immune-inflammation value linked to worse outcomes after PCI for ACS
High inflammation scores predict worse heart outcomes in patients with acute coronary syndrome
This systematic review and meta-analysis of 18,715 adults with acute coronary syndrome undergoing PCI found that higher pan-immune-inflammat…
A new analysis shows higher inflammation markers predict death and heart failure in adults with acute coronary syndrome undergoing heart pro…
Colchicine reduces major adverse cardiovascular events in coronary artery disease without increasing serious adverse events
Low-dose colchicine reduces heart attack risk for coronary artery disease patients
This systematic review and meta-analysis evaluated colchicine in patients with coronary artery disease and acute coronary syndromes. The ana…
A large analysis shows low-dose colchicine lowers major heart events for coronary artery disease patients without increasing serious risks, …
Sirolimus and paclitaxel-coated balloons show similar outcomes for coronary in-stent restenosis
Sirolimus and paclitaxel balloons show similar results for heart disease
This GRADE-assessed systematic review and meta-analysis of 3,633 participants with coronary artery disease found no notable variations betwe…
Two drug-coated balloons for coronary artery disease work about equally well, a new analysis finds.
Polymer-free and biodegradable-polymer drug-eluting stents show comparable outcomes in PCI
New review shows polymer-free stents work like biodegradable ones for heart patients
A meta-analysis compared polymer-free drug-eluting stents (PF-DES) with biodegradable-polymer drug-eluting stents (BP-DES) in patients under…
A large study of over 11,000 patients found that polymer-free stents are just as safe as older biodegradable ones. Doctors saw no major diff…
Placlitaxel drug-coated balloons reduce MACE and revascularization versus limus-eluting stents in bifurcation lesions
Drug-coated balloons cut heart risks for side branch lesions better than stents
This meta-analysis reviews data from patients with side branch lesions in true coronary bifurcations undergoing percutaneous coronary interv…
A review of 898 patients shows drug-coated balloons significantly reduce heart risks compared to stents for specific coronary artery blockag…
Breast arterial calcification on mammography predicts higher cardiovascular event risk in women
Calcium on mammograms signals higher heart risk for women
This systematic review and meta-analysis evaluated breast arterial calcification (BAC) in women across approximately 25,000 participants in …
Calcium seen on mammograms links to higher heart attack risk in women. This large review found a strong connection between breast arterial c…
Mini review examines sudden cardiac death risks in marathon runners across different age groups
Marathon running links to higher heart risk in older men and full-distance participants
This mini review synthesizes evidence on sudden cardiac death (SCD) and coronary artery disease in marathon runners. The authors note that r…
A review of marathon runners shows heart risks vary by age, sex, and race distance, with most events happening near the finish.
Serum resistin levels rise progressively with worsening severity of coronary heart disease and acute myocardial infarction in this meta-analysis
High blood resistin levels linked to heart disease severity in large analysis
A network meta-analysis of 9,169 subjects reveals that serum resistin levels increase stepwise as coronary heart disease severity worsens. W…
A large network meta-analysis found that higher serum resistin levels are linked to worse coronary heart disease and acute heart attacks.
Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
Vaccination Before Infection Cuts Heart and Stroke Risks in COVID Patients
This systematic review and meta-analysis examined the association between pre-infection COVID-19 vaccination and cardiovascular outcomes in …
Pre-infection COVID-19 vaccination significantly lowers risks of heart attacks, strokes, and other cardiovascular events in infected individ…
Questions about Percutaneous Coronary Intervention
Can an AI model help doctors decide on my treatment plan for Percutaneous Coronary Intervention?
AI models are not yet proven to help doctors decide on PCI treatment plans; current research focuses on imaging and risk scores, not AI decision support.
Full answer →Does a higher dose of heparin during elective PCI reduce bleeding complications?
Current evidence does not show that a higher heparin dose reduces bleeding; lower doses may be safer, but definitive results from the HD-PCI trial are pending.
Full answer →Will stopping aspirin early after my Percutaneous Coronary Intervention cause a heart attack?
Stopping aspirin early after PCI may increase heart attack risk if no other antiplatelet is used, but switching to a P2Y12 inhibitor alone within 3 months does not significantly raise MI risk and reduces bleeding.
Full answer →Can using intravascular imaging reduce my risk of major adverse events after PCI?
Yes, using intravascular imaging (IVUS or OCT) to guide PCI significantly reduces the risk of major adverse cardiovascular events compared to angiography alone.
Full answer →Does having metabolic syndrome increase my risk of restenosis after Percutaneous Coronary Intervention?
Current evidence does not show a clear link between metabolic syndrome and higher restenosis risk after PCI, though related factors like insulin resistance may play a role.
Full answer →