Research across Obstetric Labor Complications
Related studies from across the Obstetric Labor Complications family.
Antenatal corticosteroids provide substantial neonatal benefits for threatened preterm birth despite uncertain long-term effects
Maternal Stress and Placental Hormones May Impact Child Development
This narrative review examines the impact of maternal psychological distress, placental glucocorticoid pathways, and antenatal corticosteroi…
Research explores how maternal stress and placental hormone pathways may influence the brain development and behavior of children born prema…
Multisensory interventions improve neurodevelopmental outcomes in preterm infants compared to standard or unisensory care
Multisensory Interventions Improve Neurodevelopmental Outcomes for Preterm Infants
This meta-analysis of 13 studies found that multisensory interventions significantly improved neurodevelopmental outcomes in preterm infants…
New research suggests that infants born prematurely may see better neurodevelopmental outcomes when receiving multisensory care in the NICU.
Early Full Enteral Feeding Cuts Preterm Hospital Stay
Early full feeding may shorten hospital stays for preterm infants
Meta-analysis of 2,777 preterm infants shows early full enteral feeding reduces hospital stay by 4.41 days, with low-certainty evidence.
Starting full enteral feeding immediately after birth may help stable preterm babies reach milestones faster and leave the hospital sooner.
Respiratory trajectories vary by gestational age in infants born before 26 weeks' gestation
New data tracks breathing progress for very premature infants
This post-hoc exploratory analysis of a randomized controlled trial involved 601 infants born before 26 weeks' gestation receiving surfactan…
A new look at clinical data helps doctors better predict and manage breathing needs for babies born before 26 weeks of pregnancy.
Preterm birth linked to higher pain intensity and heat pain thresholds in meta-analysis
Preterm birth may be linked to higher pain levels in adults
This meta-analysis of 731 participants found that individuals born preterm report higher pain intensity and have higher heat pain thresholds…
People born prematurely may experience different sensations of heat and pain as they grow into adulthood.
Topical emollient application improves skin integrity and topical oil reduces sepsis risk in preterm neonates
Topical Oil May Reduce Sepsis Risk in Preterm Infants
This meta-analysis of 5,586 preterm neonates found that topical emollients significantly improved skin integrity (SMD -1.11). While overall …
Applying topical oils may improve skin health and reduce sepsis risk in preterm babies, according to a review of over 5,000 infants.
NICU noise levels frequently exceed recommended limits and primarily originate from alarms and respiratory devices
NICU noise levels often exceed safety limits for preterm infants
This systematic review of 113 studies identifies alarm systems and respiratory support as primary sources of high-level noise in NICUs. Whil…
Most neonatal intensive care units have noise levels much higher than recommended, especially from alarms and breathing equipment.
Interdisciplinary early developmental intervention programs may offer small benefits for selective attention and behavioral problems in preterm children
Early programs may help some preterm children but not all developmental areas
This systematic review and meta-analysis evaluated interdisciplinary early developmental intervention programs (EI) for children born preter…
A review of 2,315 infants suggests early developmental programs may help attention and behavior, but show little effect on language or schoo…
Meta-analysis shows early kangaroo care reduces mortality in very preterm infants compared to conventional care
Early skin-to-skin contact may lower death risk for very preterm babies
This systematic review and meta-analysis evaluated early kangaroo care versus conventional neonatal care in very preterm infants (≤32 weeks)…
A review of trials found that starting skin-to-skin care within 24 hours reduced death risk for very preterm infants, though effects on infe…
Individual patient data meta-analysis on preterm birth risk in asymptomatic pregnant individuals with prior spontaneous preterm birth
Women with prior preterm birth may need less treatment if risk is low
This individual patient data meta-analysis synthesized data from 1316 patients across 7 data sets to assess recurrent spontaneous preterm bi…
A new analysis shows doctors can better predict who needs extra care after a preterm birth while sparing others from unnecessary treatment
Systematic review finds uncertain benefit of olfactory stimulation in preterm infants
Smells May Help Preterm Infants Feed and Breathe Better
This systematic review of 14 trials involving 1087 preterm infants assessed olfactory stimulation with various odors. Evidence was very low …
A review of 14 trials suggests that certain odors, like breast milk or vanilla, may slightly reduce apnea and shorten hospital stays in pret…
Preterm children aged 0–2 years show lower growth rates and IGF-1 levels compared to full-term peers
Preterm babies grow slower due to biology and environment factors
This cohort study followed preterm children aged 0–2 years and compared them to full-term children.
New research shows biology and environment slow preterm baby growth, giving doctors better tools to help them catch up.