Research across Obstetric Labor Complications
Related studies from across the Obstetric Labor Complications family.
NICU noise levels frequently exceed recommended limits and primarily originate from alarms and respiratory devices
NICU noise levels often exceed safety limits for preterm infants
This systematic review of 113 studies identifies alarm systems and respiratory support as primary sources of high-level noise in NICUs. Whil…
Most neonatal intensive care units have noise levels much higher than recommended, especially from alarms and breathing equipment.
Interdisciplinary early developmental intervention programs may offer small benefits for selective attention and behavioral problems in preterm children
Early programs may help some preterm children but not all developmental areas
This systematic review and meta-analysis evaluated interdisciplinary early developmental intervention programs (EI) for children born preter…
A review of 2,315 infants suggests early developmental programs may help attention and behavior, but show little effect on language or schoo…
Meta-analysis shows early kangaroo care reduces mortality in very preterm infants compared to conventional care
Early skin-to-skin contact may lower death risk for very preterm babies
This systematic review and meta-analysis evaluated early kangaroo care versus conventional neonatal care in very preterm infants (≤32 weeks)…
A review of trials found that starting skin-to-skin care within 24 hours reduced death risk for very preterm infants, though effects on infe…
Individual patient data meta-analysis on preterm birth risk in asymptomatic pregnant individuals with prior spontaneous preterm birth
Women with prior preterm birth may need less treatment if risk is low
This individual patient data meta-analysis synthesized data from 1316 patients across 7 data sets to assess recurrent spontaneous preterm bi…
A new analysis shows doctors can better predict who needs extra care after a preterm birth while sparing others from unnecessary treatment
Preterm children aged 0–2 years show lower growth rates and IGF-1 levels compared to full-term peers
Preterm babies grow slower due to biology and environment factors
This cohort study followed preterm children aged 0–2 years and compared them to full-term children.
New research shows biology and environment slow preterm baby growth, giving doctors better tools to help them catch up.
Extended Caffeine Therapy Reduces Intermittent Hypoxia Burden in Very Preterm Infants in Randomized Trial
Giving Caffeine a Longer Ride
This randomized clinical trial enrolled 160 infants <30 weeks + 6 days gestational age to evaluate extended caffeine therapy versus placebo.
Extending caffeine treatment for premature babies until 43 weeks reduced dangerous oxygen drops and lowered inflammation markers.
Full milk feeds from birth show no difference in hospital stay but lower costs for preterm infants
Does feeding preterm babies full milk from birth shorten their hospital stay?
This randomized controlled trial in 2088 preterm infants born at 30+0 to 32+6 weeks' gestation compared full milk feeds from birth to gradua…
Starting full milk feeds from birth for preterm babies costs slightly less but does not shorten hospital stays compared to gradual feeding w…
Factors associated with time to discharge among preterm neonates in a Ugandan NICU retrospective cohort study
Why Some Preterm Babies Stay in the NICU Longer
This retrospective cohort study analyzed 847 preterm neonates admitted to a Ugandan NICU to identify predictors of discharge.
Better prenatal care and local support help preterm babies go home sooner, with 70% leaving the hospital within four weeks in rural Uganda.
Systematic review examines placental biology and social context in Black and African American women with pregnancy complications
The Organ That Records Stress, Racism, and Poverty — Before Birth
This systematic review investigates factors including placental biology, genetic variation, and socioeconomic exposures among Black and Afri…
The placenta records stress, racism, and poverty before birth, shaping higher complication rates for Black women through biology shaped by t…
Review of Treg-targeting strategies for pregnancy complications lacks reported outcomes or safety data
Review of Treg therapies for pregnancy complications shows mixed early results
This narrative review examines therapeutic strategies targeting regulatory T cells (Tregs) for conditions including recurrent implantation f…
New therapies targeting immune cells called Tregs show early promise for pregnancy complications like miscarriage and pre-eclampsia, but evi…
Gut microbiota signatures in preterm infants correlate with neurodevelopmental impairment risk at three months corrected age
Tiny Gut Clues May Predict Brain Risks in Preemies
This prospective, matched, longitudinal multi-omics study evaluated preterm infants to identify early biomarkers for neurodevelopmental impa…
A simple stool sample from a preterm baby may one day reveal who needs extra brain support long before any symptoms show up.
Self-reported racial discrimination associated with postpartum depression and low birth weight in pregnant women
Discrimination Linked to Baby's Low Weight and Mom's Mood
This systematic review and meta-analysis of 1,473,417 participants assessed associations between self-reported interpersonal racial discrimi…
Experiencing racism during pregnancy is a serious health risk that doctors must address to keep moms and babies safe.