Research across Obstetric Labor Complications
Related studies from across the Obstetric Labor Complications family.
Preterm birth linked to higher pain intensity and heat pain thresholds in meta-analysis
Preterm birth may be linked to higher pain levels in adults
This meta-analysis of 731 participants found that individuals born preterm report higher pain intensity and have higher heat pain thresholds…
People born prematurely may experience different sensations of heat and pain as they grow into adulthood.
Topical emollient application improves skin integrity and topical oil reduces sepsis risk in preterm neonates
Topical Oil May Reduce Sepsis Risk in Preterm Infants
This meta-analysis of 5,586 preterm neonates found that topical emollients significantly improved skin integrity (SMD -1.11). While overall …
Applying topical oils may improve skin health and reduce sepsis risk in preterm babies, according to a review of over 5,000 infants.
NICU noise levels frequently exceed recommended limits and primarily originate from alarms and respiratory devices
NICU noise levels often exceed safety limits for preterm infants
This systematic review of 113 studies identifies alarm systems and respiratory support as primary sources of high-level noise in NICUs. Whil…
Most neonatal intensive care units have noise levels much higher than recommended, especially from alarms and breathing equipment.
Interdisciplinary early developmental intervention programs may offer small benefits for selective attention and behavioral problems in preterm children
Early programs may help some preterm children but not all developmental areas
This systematic review and meta-analysis evaluated interdisciplinary early developmental intervention programs (EI) for children born preter…
A review of 2,315 infants suggests early developmental programs may help attention and behavior, but show little effect on language or schoo…
Meta-analysis shows early kangaroo care reduces mortality in very preterm infants compared to conventional care
Early skin-to-skin contact may lower death risk for very preterm babies
This systematic review and meta-analysis evaluated early kangaroo care versus conventional neonatal care in very preterm infants (≤32 weeks)…
A review of trials found that starting skin-to-skin care within 24 hours reduced death risk for very preterm infants, though effects on infe…
Individual patient data meta-analysis on preterm birth risk in asymptomatic pregnant individuals with prior spontaneous preterm birth
Women with prior preterm birth may need less treatment if risk is low
This individual patient data meta-analysis synthesized data from 1316 patients across 7 data sets to assess recurrent spontaneous preterm bi…
A new analysis shows doctors can better predict who needs extra care after a preterm birth while sparing others from unnecessary treatment
Systematic review finds uncertain benefit of olfactory stimulation in preterm infants
Smells May Help Preterm Infants Feed and Breathe Better
This systematic review of 14 trials involving 1087 preterm infants assessed olfactory stimulation with various odors. Evidence was very low …
A review of 14 trials suggests that certain odors, like breast milk or vanilla, may slightly reduce apnea and shorten hospital stays in pret…
Preterm children aged 0–2 years show lower growth rates and IGF-1 levels compared to full-term peers
Preterm babies grow slower due to biology and environment factors
This cohort study followed preterm children aged 0–2 years and compared them to full-term children.
New research shows biology and environment slow preterm baby growth, giving doctors better tools to help them catch up.
Continuous glucose monitoring in very preterm infants shows low ketones and higher lactate in first week
Study looks at glucose monitoring and metabolites in very preterm infants
This prespecified substudy of an RCT in 168 very low birth weight infants found consistently low ketone concentrations and higher lactate co…
Very preterm infants show high lactate levels that drop in a week, while ketones stay low with no clear link to blood sugar or insulin treat…
Closed-loop oxygen control shortens ventilation and oxygen duration in preterm infants in RCT
New Technology Helps Preterm Babies Spend Less Time on Ventilators
This randomized controlled trial in 69 preterm infants compared closed-loop automated oxygen control to manual control.
A smart oxygen system helped preterm babies breathe on their own sooner, cutting ventilator time and reducing lung disease risk.
Extended Caffeine Therapy Reduces Intermittent Hypoxia Burden in Very Preterm Infants in Randomized Trial
Giving Caffeine a Longer Ride
This randomized clinical trial enrolled 160 infants <30 weeks + 6 days gestational age to evaluate extended caffeine therapy versus placebo.
Extending caffeine treatment for premature babies until 43 weeks reduced dangerous oxygen drops and lowered inflammation markers.
Full milk feeds from birth show no difference in hospital stay but lower costs for preterm infants
Does feeding preterm babies full milk from birth shorten their hospital stay?
This randomized controlled trial in 2088 preterm infants born at 30+0 to 32+6 weeks' gestation compared full milk feeds from birth to gradua…
Starting full milk feeds from birth for preterm babies costs slightly less but does not shorten hospital stays compared to gradual feeding w…