Meta-analysis of nutrition education in adult dialysis patients shows improved knowledge and quality of life
Simple Diet Lessons Help Dialysis Patients Feel Better
This meta-analysis of trials in adult dialysis patients found that nutrition education interventions significantly improved knowledge and he…
Teaching patients about their food needs can improve how they feel and what they know.
Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
Kidney Damage May Start With Fat in the Wrong Places
This systematic review summarizes mechanisms and therapeutic strategies targeting renal ELD across kidney diseases, including diabetic and…
This research explains how fat in the wrong kidney cells causes harm, opening new paths for prevention and treatment.
Review summarizes therapeutic strategies targeting cGAS-STING-macrophage axis for renal fibrosis and chronic kidney disease
New Kidney Damage Pathway Discovered—And Scientists Are Already Blocking It
This narrative review examines emerging therapeutic strategies targeting the cGAS-STING-macrophage axis for renal fibrosis and chronic kidne…
This research reveals a new way to stop kidney damage before it leads to failure.
Updated PIRCHE-T2 model improves dnDSA risk stratification in kidney transplant recipients
New Tool Predicts Kidney Rejection Risk With More Accuracy
This observational cohort study in 1581 kidney transplant recipients from Zurich and Basel found that an updated PIRCHE-T2 model improved de…
A smarter computer model helps doctors choose safer kidney donors.
24-hour diastolic BP variability linked to renal decline in diabetic kidney disease
Why Your Blood Pressure Swings Matter More Than Numbers
This retrospective cohort study of 2143 patients with diabetic kidney disease found that each 1 mmHg increase in 24-hour diastolic blood pre…
Stability matters more than the number itself when protecting kidneys.
O. vulgatum consumption linked to rhabdomyolysis and acute kidney injury in 10 patients
This Common Herb May Cause Dangerous Muscle Breakdown
This retrospective case series of 10 patients at a Chinese hospital found that O.
A traditional herbal soup can cause severe muscle breakdown, but stopping use leads to full recovery.
FluxPro-DKD fusion model integration shows higher AUC for early-stage DKD detection in type 2 diabetes
New fusion model spots early kidney disease in diabetes better than standard care
This multicenter cohort study evaluated 364 participants with type 2 diabetes using the FluxPro-DKD fusion model versus a standard clinical …
A new digital model found early kidney disease in people with diabetes more accurately than standard clinical tools, offering hope for earli…
Single-centre observational study on hemodialysis duration and outcomes in end-stage renal disease
Shorter Dialysis Sessions May Offer Better Quality of Life for Older Patients
This observational study in 140 adults on hemodialysis compared less than 720 minutes per week to 720 minutes or more.
Shorter dialysis sessions may improve daily life for older patients without increasing their risk of death, offering a gentler approach to a…
Meta-analysis links chronic kidney disease to higher mortality after intracerebral hemorrhage
Kidney Disease Linked to Higher Stroke Death Risk
This meta-analysis of 5,000 patients with spontaneous intracerebral hemorrhage found that chronic kidney disease was associated with higher …
Kidney disease makes surviving a brain bleed much harder, raising the risk of death and disability for patients with this common condition.
Elevated TyG index linked to renal deterioration in CKD and hypertensive cohorts
Could a simple blood sugar marker signal kidney trouble years ahead?
This prospective cohort study of 4,476 community and 396 hospital-based CKD patients found an independent association between a higher basel…
A simple blood sugar marker called the TyG index predicts kidney trouble years ahead, especially when combined with high blood pressure.
Meta-analysis of 24 animal studies shows emodin reduces kidney injury markers in preclinical models
Animal studies suggest emodin may lower kidney injury markers, but human data is missing
This systematic review and meta-analysis evaluated 24 preclinical studies involving 408 animals (396 rodents, 12 canines) to assess emodin's…
Animal studies show emodin lowers kidney injury markers, but high doses or long-term use caused toxicity, meaning human safety is still unpr…
Gastrointestinal complications in cardiac surgery patients are linked to high mortality and multiorgan failure
A Hidden Danger After Heart Surgery That Doctors Can Now Predict
This retrospective case–control study examined 162 matched patients undergoing cardiac surgery.
A new risk score using age, smoking, kidney disease, and valve surgery can predict deadly gut complications after heart operations that kill…
Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
Sepsis may damage kidneys by letting gut bacteria toxins leak into the blood
This narrative review examines the role of gut microbiota dysbiosis in sepsis-associated acute kidney injury and acute kidney injury. The au…
A review suggests that sepsis changes gut bacteria, causing harmful toxins to leak and hurt kidneys in humans and animals.
Meta-analysis of sirolimus for cutaneous squamous cell carcinoma in kidney transplant recipients
Sirolimus lowers skin cancer risk in kidney transplant patients
This meta-analysis of four randomized trials in kidney transplant recipients with prior cutaneous squamous cell carcinoma found that switchi…
A review of studies shows switching to sirolimus can cut skin cancer rates, but it may cause more side effects.
Review of environmental exposures in agricultural communities with chronic kidney disease of unknown cause
New research hunts the hidden causes of kidney disease in farming communities
This publication is a review examining potential environmental exposures in agricultural communities in Central America and South Asia. The …
A new study hunts for the hidden causes of kidney disease in farming communities across Central America and South Asia.
Oral beraprost extends median survival in dogs with IRIS stage 2 chronic kidney disease compared to historical controls
Beraprost Adds Years to Dogs’ Lives with Early Kidney Disease
This prospective clinical study evaluated oral beraprost in dogs with naturally occurring IRIS stage 2 chronic kidney disease.
Dogs with early kidney disease who took a certain medication lived more than five times longer than those who didn’t — and vets are taking n…
Narrative review supports SGLT-2i use in cardiovascular-kidney-metabolic syndrome
New Treatment Shifts How We Fight Heart, Kidney, and Diabetes Damage
This narrative review summarizes evidence on SGLT-2 inhibitors for patients with stages 2–4 cardiovascular-kidney-metabolic syndrome.
Maria, 58, has type 2 diabetes and high blood pressure.
Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
A Simple Body Measurement May Reveal Your Hidden Health Risk
This systematic review and meta-analysis of 93 observational studies from 13 countries evaluated the body roundness index (BRI) against conv…
A simple math formula using your height and waist size may help doctors catch silent health problems long before they turn serious.
Higher cumulative inflammatory-metabolic index linked to increased risk of rapid kidney function decline in older adults
A Simple Blood Test May Now Predict Your Kidney Health Years Earlier
A cohort study of 6,888 middle-aged and older adults found that each one-unit increase in cumulative C-reactive protein-triglyceride glucose…
A simple blood test combining inflammation and sugar levels can predict rapid kidney decline years before serious damage occurs in adults.
Modified cardiometabolic index predicts mortality in adults with cardiovascular-kidney-metabolic syndrome better than traditional indices
New Score Predicts Heart and Kidney Risk Better Than Old Tests
This prospective cohort study of 5,189 adults with cardiovascular-kidney-metabolic syndrome assessed the modified cardiometabolic index (MCM…
A new health score predicts heart and kidney failure risk better than standard blood tests, revealing hidden dangers in millions of patients…
Biological age acceleration linked to faster progression from cardiovascular-kidney-metabolic disease to dementia
Your Body Might Be Older Than Your Birthday Says
A prospective cohort study of 433,911 UK Biobank participants found biological age acceleration was associated with increased risk of transi…
People whose biological age ran ahead of their calendar age moved faster through a chain of chronic diseases that ended in dementia or earli…
Higher BUN/Cr ratio linked to increased mortality in older patients with sepsis-associated AKI
A Simple Blood Test Ratio Could Predict Survival in Severe Infections
A retrospective cohort study of 764 patients aged ≥50 years with sepsis-associated AKI found each 1-unit increase in BUN/Cr ratio was associ…
A simple blood test ratio linked to kidney failure in severe infections now helps doctors predict which patients face higher survival risks.
CI-AKI in ACS patients undergoing PCI was associated with a 4.7-fold increased hazard of death within 90 days
Dye in Heart Attack Treatment Raises Death Risk
This prospective cohort study evaluated 192 patients with acute coronary syndrome treated with percutaneous coronary intervention.
A dye used to clear blocked heart arteries can damage kidneys and raise the risk of death within 90 days for patients with acute coronary sy…
UK retrospective cohort study of tolvaptan prescribing in ADPKD reveals significant variation in initiation and substantial national costs
UK Kidney Centers Miss Out on Life-Saving Drug for Millions
This retrospective cohort study analyzed tolvaptan prescribing patterns among 3,609 people with autosomal dominant polycystic kidney disease…
Over 12 million people with a genetic kidney disease worldwide are missing out on a life-saving drug because UK doctors aren't always prescr…
Questions about Chronic Kidney Disease
Does taking NSAIDs during pregnancy increase the risk of kidney disease in my child?
A large review of seven studies found that taking NSAIDs during pregnancy is linked to a higher risk of kidney disease in children, with the risk increasing when used in the second and third trimesters.
Full answer →Are there new guidelines for kidney cancer based on recent 2025 trials?
Yes, the 2025 EAU guidelines update kidney cancer care with new recommendations on stereotactic body radiotherapy, adjuvant therapy, and systemic treatments for clear-cell and hereditary RCC.
Full answer →How can artificial intelligence help patients with kidney cancer in surgery?
Artificial intelligence helps kidney cancer patients by improving tumor detection on scans, planning robotic surgeries, and predicting surgical outcomes to reduce complications.
Full answer →Are complication risks for kidney stone surgery higher in elderly patients?
Yes, elderly patients have higher risks of sepsis after PCNL, but overall complication rates are similar to younger patients for most kidney stone surgeries.
Full answer →Do complement pathways play a role in kidney diseases affecting my transplant?
Yes, complement pathways are involved in kidney transplant rejection, including antibody-mediated rejection, and may be targeted for therapy.
Full answer →What mechanisms link obesity to inflammation in chronic kidney disease?
Obesity fuels kidney inflammation through adipose tissue dysfunction, lipotoxicity, altered secretion of inflammatory factors, and gut-derived uremic toxins, creating a vicious cycle that worsens chronic kidney disease.
Full answer →Can layered data models help doctors find my risk for diabetic kidney disease earlier?
Yes, layered data models that combine clinical, lab, medication, and social data can help doctors detect diabetic kidney disease risk earlier than traditional methods alone.
Full answer →Can a machine learning model find hidden diabetic kidney disease while I am hospitalized?
Yes, a machine learning model using routine hospital data can detect hidden diabetic kidney disease, even when standard tests appear normal.
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