Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
A Simple Body Measurement May Reveal Your Hidden Health Risk
This systematic review and meta-analysis of 93 observational studies from 13 countries evaluated the body roundness index (BRI) against conv…
A simple math formula using your height and waist size may help doctors catch silent health problems long before they turn serious.
Cross-Sectional Analysis of Protective Foot Sensation and Complications in 387 Type 2 Diabetes Patients
Smoking and kidney disease link to worse diabetes nerve damage in feet
This retrospective cross-sectional study evaluated 387 patients with Type 2 diabetes and Diabetic Peripheral Neuropathy at University Hospit…
Smoking and severe kidney disease greatly increase the risk of losing protective feeling in the feet, leading to dangerous complications for…
Atherogenic index of plasma shows non-linear association with mortality in diabetic AKI patients
Research finds blood marker linked to death in diabetic kidney injury
A retrospective cohort study of 1046 diabetic patients with acute kidney injury found that the atherogenic index of plasma (AIP) had a non-l…
Higher levels of a specific blood marker are linked to a greater risk of death in people with diabetes and acute kidney injury.
Total IgG Concentration Linked to Anemia in Hemodialysis Patients
Is low immunity linked to anemia in dialysis patients, or just age?
This cross-sectional study included 351 participants, comprising 179 dialysis patients and 172 healthy controls.
Dialysis patients with weaker overall immune defenses are more likely to have anemia, while protection from chickenpox offers little clue ab…
Cryopreserved venous allografts increased cold ischemia time in living-donor kidney transplant recipients
Does stretching a kidney vein during transplant add dangerous wait time for the organ?
This preliminary cohort study examined living-donor kidney transplant recipients and donors at two regional university hospitals.
Using cryopreserved veins to fix short donor kidney vessels adds nearly two hours to the organ's wait time before it reaches the recipient.
Minimum immunobiology packages may improve kidney transplant safety and equity in low- and middle-income settings
Sri Lanka Shows How Safer Kidney Transplants Are Possible Anywhere
This narrative review examined kidney transplantation practices in low- and middle-income settings, specifically Sri Lanka.
A new roadmap helps low-resource hospitals match wealthy countries' kidney transplant results using simple lab tools.
Physical exercise reduces all-cause mortality and improves outcomes in chronic kidney disease patients
Exercise linked to lower death risk and better health in chronic kidney disease patients
This systematic review and meta-analysis of 82 randomized controlled trials involving chronic kidney disease patients, including those on di…
Regular exercise lowers death risk and improves heart, lung, and blood health for people with chronic kidney disease.
Narrative review suggests coordinated care models may strengthen European primary health care systems
Poland's New Health Plan: A Major Shift for Chronic Care
This narrative review examines the Coordinated Care model within Primary Health Care systems in Europe, specifically Poland.
Poland launched a new coordinated care model in 2022 that connects patients with specialists and labs to manage chronic conditions like diab…
Multimodal AI applications in urologic oncology for prostate, bladder, and kidney cancers
Smarter Cancer Care: How AI Is Learning to See the Whole Picture
This narrative review examines multimodal artificial intelligence (AI) applications in urologic oncology for patients with prostate, bladder…
New AI tools combine scans, biopsies, and genes to give clearer answers for prostate, bladder, and kidney cancer patients, though most are s…
Meta-analysis identifies risk factors for diabetic kidney disease in Asian patients with type 2 diabetes
High Blood Pressure Is A Major Kidney Killer For Asian Diabetics
A meta-analysis of 24 studies including 12,047 Asian patients with type 2 diabetes found that SBP, hypertension, HbA1c, WHR, FBG, UA, Cr, ag…
High blood pressure is a top kidney killer for Asian diabetics, making blood pressure control just as critical as managing sugar levels to p…
NIID patients with kidney injury show higher immune markers compared to those without kidney injury
Kidney Pain in NIID Linked to Immune Fire
This retrospective cohort study analyzed 150 genetically confirmed Neuronal intranuclear inclusion disease (NIID) patients across nine terti…
Doctors can now spot kidney trouble in Neuronal Intranuclear Inclusion Disease (NIID) by looking for a specific type of immune fire rather t…
Proenkephalin A levels show no correlation with kidney or cardiac markers in hemodialysis patients
PENK Levels Don't Predict Kidney Function in Dialysis
A prospective cohort study of 100 adult patients with end-stage kidney disease undergoing maintenance hemodialysis found no significant corr…
A popular kidney marker called PENK fails to track function in patients already on dialysis, making it useless for monitoring their health.
Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
Sepsis may damage kidneys by letting gut bacteria toxins leak into the blood
This narrative review examines the role of gut microbiota dysbiosis in sepsis-associated acute kidney injury and acute kidney injury. The au…
A review suggests that sepsis changes gut bacteria, causing harmful toxins to leak and hurt kidneys in humans and animals.
Meta-analysis of sirolimus for cutaneous squamous cell carcinoma in kidney transplant recipients
Sirolimus lowers skin cancer risk in kidney transplant patients
This meta-analysis of four randomized trials in kidney transplant recipients with prior cutaneous squamous cell carcinoma found that switchi…
A review of studies shows switching to sirolimus can cut skin cancer rates, but it may cause more side effects.
Review of environmental exposures in agricultural communities with chronic kidney disease of unknown cause
New research hunts the hidden causes of kidney disease in farming communities
This publication is a review examining potential environmental exposures in agricultural communities in Central America and South Asia. The …
A new study hunts for the hidden causes of kidney disease in farming communities across Central America and South Asia.
Oral beraprost extends median survival in dogs with IRIS stage 2 chronic kidney disease compared to historical controls
Beraprost Adds Years to Dogs’ Lives with Early Kidney Disease
This prospective clinical study evaluated oral beraprost in dogs with naturally occurring IRIS stage 2 chronic kidney disease.
Dogs with early kidney disease who took a certain medication lived more than five times longer than those who didn’t — and vets are taking n…
Narrative review supports SGLT-2i use in cardiovascular-kidney-metabolic syndrome
New Treatment Shifts How We Fight Heart, Kidney, and Diabetes Damage
This narrative review summarizes evidence on SGLT-2 inhibitors for patients with stages 2–4 cardiovascular-kidney-metabolic syndrome.
Maria, 58, has type 2 diabetes and high blood pressure.
Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
Kidney Damage May Start With Fat in the Wrong Places
This systematic review summarizes mechanisms and therapeutic strategies targeting renal ELD across kidney diseases, including diabetic and…
This research explains how fat in the wrong kidney cells causes harm, opening new paths for prevention and treatment.
Higher cumulative inflammatory-metabolic index linked to increased risk of rapid kidney function decline in older adults
A Simple Blood Test May Now Predict Your Kidney Health Years Earlier
A cohort study of 6,888 middle-aged and older adults found that each one-unit increase in cumulative C-reactive protein-triglyceride glucose…
A simple blood test combining inflammation and sugar levels can predict rapid kidney decline years before serious damage occurs in adults.
Modified cardiometabolic index predicts mortality in adults with cardiovascular-kidney-metabolic syndrome better than traditional indices
New Score Predicts Heart and Kidney Risk Better Than Old Tests
This prospective cohort study of 5,189 adults with cardiovascular-kidney-metabolic syndrome assessed the modified cardiometabolic index (MCM…
A new health score predicts heart and kidney failure risk better than standard blood tests, revealing hidden dangers in millions of patients…
Biological age acceleration linked to faster progression from cardiovascular-kidney-metabolic disease to dementia
Your Body Might Be Older Than Your Birthday Says
A prospective cohort study of 433,911 UK Biobank participants found biological age acceleration was associated with increased risk of transi…
People whose biological age ran ahead of their calendar age moved faster through a chain of chronic diseases that ended in dementia or earli…
Higher BUN/Cr ratio linked to increased mortality in older patients with sepsis-associated AKI
A Simple Blood Test Ratio Could Predict Survival in Severe Infections
A retrospective cohort study of 764 patients aged ≥50 years with sepsis-associated AKI found each 1-unit increase in BUN/Cr ratio was associ…
A simple blood test ratio linked to kidney failure in severe infections now helps doctors predict which patients face higher survival risks.
CI-AKI in ACS patients undergoing PCI was associated with a 4.7-fold increased hazard of death within 90 days
Dye in Heart Attack Treatment Raises Death Risk
This prospective cohort study evaluated 192 patients with acute coronary syndrome treated with percutaneous coronary intervention.
A dye used to clear blocked heart arteries can damage kidneys and raise the risk of death within 90 days for patients with acute coronary sy…
UK retrospective cohort study of tolvaptan prescribing in ADPKD reveals significant variation in initiation and substantial national costs
UK Kidney Centers Miss Out on Life-Saving Drug for Millions
This retrospective cohort study analyzed tolvaptan prescribing patterns among 3,609 people with autosomal dominant polycystic kidney disease…
Over 12 million people with a genetic kidney disease worldwide are missing out on a life-saving drug because UK doctors aren't always prescr…
Questions about Chronic Kidney Disease
Does taking NSAIDs during pregnancy increase the risk of kidney disease in my child?
A large review of seven studies found that taking NSAIDs during pregnancy is linked to a higher risk of kidney disease in children, with the risk increasing when used in the second and third trimesters.
Full answer →Are there new guidelines for kidney cancer based on recent 2025 trials?
Yes, the 2025 EAU guidelines update kidney cancer care with new recommendations on stereotactic body radiotherapy, adjuvant therapy, and systemic treatments for clear-cell and hereditary RCC.
Full answer →How can artificial intelligence help patients with kidney cancer in surgery?
Artificial intelligence helps kidney cancer patients by improving tumor detection on scans, planning robotic surgeries, and predicting surgical outcomes to reduce complications.
Full answer →Are complication risks for kidney stone surgery higher in elderly patients?
Yes, elderly patients have higher risks of sepsis after PCNL, but overall complication rates are similar to younger patients for most kidney stone surgeries.
Full answer →Do complement pathways play a role in kidney diseases affecting my transplant?
Yes, complement pathways are involved in kidney transplant rejection, including antibody-mediated rejection, and may be targeted for therapy.
Full answer →What mechanisms link obesity to inflammation in chronic kidney disease?
Obesity fuels kidney inflammation through adipose tissue dysfunction, lipotoxicity, altered secretion of inflammatory factors, and gut-derived uremic toxins, creating a vicious cycle that worsens chronic kidney disease.
Full answer →Can layered data models help doctors find my risk for diabetic kidney disease earlier?
Yes, layered data models that combine clinical, lab, medication, and social data can help doctors detect diabetic kidney disease risk earlier than traditional methods alone.
Full answer →Can a machine learning model find hidden diabetic kidney disease while I am hospitalized?
Yes, a machine learning model using routine hospital data can detect hidden diabetic kidney disease, even when standard tests appear normal.
Full answer →