Imiquimod TLR7 stimulation shows sex-specific immune responses in HIV and non-HIV populations
Research shows immune reactions to imiquimod vary between men and women with HIV
This cohort study evaluated TLR7 stimulation with imiquimod in 1,326 individuals living with HIV and 43 people without HIV. Women living wit…
Women with HIV show different immune reactions to imiquimod than men, suggesting doctors may need to consider biological sex when developing…
Switching from EFV/TDF/3TC to B/F/TAF or DTG/3TC in virologically suppressed PLWH shows no significant between-group metabolic differences over 24 months.
Switching HIV drugs showed similar metabolic changes over two years in this real-world study.
This retrospective real-world study evaluated 326 virologically suppressed persons with HIV (PLWH) switching from efavirenz/tenofovir disopr…
Switching HIV drugs caused similar weight gain and metabolic shifts over two years, meaning lifestyle factors matter more than the specific …
Narrative review assesses AI/ML adherence prediction in chronic disease patients globally with noted limitations.
AI Can Now Predict Who Will Stop Taking Their Medication — Before They Do
This narrative review evaluates artificial intelligence and machine learning approaches for prospective adherence risk prediction in chronic…
AI tools can now predict which patients with chronic diseases like diabetes or HIV will stop taking their medication before it happens, allo…
Meta-analysis of antiretroviral therapy virologic suppression in HIV-positive pregnant and lactating women in Africa
New review shows HIV treatment success varies by age and adherence
This systematic review and meta-analysis evaluated virologic suppression among 304,883 HIV-positive pregnant and lactating women in Africa. …
In Africa, HIV treatment success for women varies by age and medicine adherence, with only 60.92% reaching the ideal undetectable viral load…
Systematic review finds intestinal microenvironment abnormalities are more severe in HIV immunological non-responders compared to responders.
HIV Treatment Leaves Some Patients Behind. Here's Why.
This systematic review evaluated intestinal immune and microbial differences between people living with HIV (PLWH) classified as immunologic…
Some HIV patients stay vulnerable to illness even after years of successful treatment because their damaged gut fails to rebuild immunity.
Nomogram using baseline SUA and CD4+ count predicts hyperuricemia risk in people living with HIV
What raises uric acid in HIV? New tool spots risk before symptoms start.
This retrospective single-center study in Hangzhou, China derived and internally validated a nomogram predicting time to hyperuricemia (HUA)…
A new tool predicts high uric acid risk in HIV patients using just two factors: starting uric acid levels and CD4+ T-cell counts.
Cochrane review: injectable lenacapavir cuts HIV infections versus oral PrEP at 52 weeks
One Shot Saves You From HIV For Six Months
This Cochrane systematic review and meta-analysis of two randomised controlled trials (8660 participants) compared six-monthly subcutaneous …
A single shot under the skin protects against HIV for six months, solving the daily pill problem for millions at risk.
Nevirapine plus lamivudine and zidovudine improved lymphocyte counts and reduced adverse effects versus efavirenz in HIV patients.
New HIV drug combo showed fewer side effects and better immune markers in small trial
This randomized controlled trial enrolled 100 patients with HIV/AIDS in a hospital setting. Participants received either lamivudine plus zid…
A new HIV drug combo boosted immune cells and caused fewer side effects than the standard alternative in a recent trial.
High-volume interval exercise linked to higher enjoyment in people with HIV versus healthy controls
High-intensity interval exercise boosted enjoyment in people living with HIV compared to healthy controls
A single-blind crossover study of 11 people living with HIV and 11 healthy controls found that high-volume high-intensity interval exercise …
People living with HIV reported higher enjoyment during high-volume intense workouts compared to healthy controls in a new study.
Pitavastatin showed no difference in health-related quality of life compared with placebo in people with HIV.
Why Heart Risk Factors Drag Down Daily Wellbeing for People With HIV
This randomized controlled trial evaluated pitavastatin versus placebo in 733 people with HIV aged 40 to 75 years on antiretroviral therapy …
Common heart risks like smoking and high BMI hurt daily physical wellbeing for people with HIV, while statins showed no visible improvement …
Mental health syndemics reduce ART adherence and impair viral suppression in people living with HIV.
When HIV and Depression Collide, Treatment Suffers
This systematic review and meta-analysis of 32 studies involving people living with HIV (PLWH) examined the impact of mental health-related …
When depression, trauma, and poverty pile onto HIV, people struggle more to take their meds and keep the virus in check.
Mindfulness-based cognitive therapy improved happiness and mood in women living with HIV compared to control.
Mindfulness Boosts Happiness for Women Living with HIV
This randomized controlled trial enrolled 92 women living with HIV in Ahvaz, Iran. Participants receiving mindfulness-based cognitive therap…
A mental workout called mindfulness therapy significantly lifted happiness and reduced depression for women living with HIV in Iran.