Personalized nutrition and behavioral correction address feline obesity and associated comorbidities like diabetes and osteoarthritis.
Review finds personalized nutrition and exercise help manage cat obesity and related health issues
This systematic review evaluated determinants, diagnosis, pathophysiology, and management of obesity in domestic cats. Overweight and obesit…
Personalized nutrition and exercise plans help manage cat obesity, a common disorder that raises risks for diabetes and other serious health…
HFpEF probability scores rule out disease but show limitations in AF and obesity phenotypes.
HFpEF probability scores work well for typical cases but struggle with atrial fibrillation and obesity
This systematic review evaluated the performance of HFpEF probability scores (HFA-PEFF and H2FPEF) in patients with heart failure with prese…
Heart failure scores work well for typical cases but lose accuracy in patients with atrial fibrillation or obesity due to altered biological…
Elevated plasma phenylalanine associated with obesity, type 2 diabetes, and cancer risk.
High plasma phenylalanine linked to obesity, diabetes, and cancer risk
This systematic review examines epidemiological and mechanistic evidence regarding elevated plasma phenylalanine in metabolic disorders. The…
High blood phenylalanine is linked to obesity, type 2 diabetes, and cancer risk by blocking insulin signals and damaging mitochondria.
Meta-analysis finds distinct neural activation patterns to food and monetary rewards in overweight/obesity
Brain scans reveal how food and money rewards differ in people with overweight or obesity
A meta-analysis of 26 fMRI studies (1065 participants) found individuals with overweight/obesity show both overlapping and distinct neural a…
Researchers analyzed brain scan data from over 1,000 people to see how brains respond to food and money rewards. They found people with over…
Cognitive training add-on to behavioral weight-loss intervention shows moderate BMI reductions at 6 months
Cognitive training added to weight loss program shows modest benefits in small trial
A randomized trial in 148 adults with excess weight found that adding comprehensive cognitive training to standard behavioral weight-loss in…
Adding mental exercises to a weight loss program helped adults lose more weight and lower their BMI compared to standard care alone.
Calorie restriction plus exercise reduced IL-6 and knee pain more than diet alone in knee OA
Small study finds adding exercise to calorie restriction may reduce knee pain and inflammation
A 4-week RCT in 23 overweight/obese adults with knee osteoarthritis compared calorie restriction alone to restriction plus aerobic exercise.…
Adding exercise to a calorie-reduced diet lowered knee pain and a specific inflammation marker in overweight people with knee osteoarthritis…
GLP-1RAs reduce MACE risk in Asian and White adults with diabetes or overweight
Do heart benefits from diabetes drugs work equally well across different races?
A meta-analysis of 74,703 adults with type 2 diabetes or overweight/obesity found GLP-1RAs reduced MACE risk versus placebo. The reduction w…
Diabetes drugs protect hearts in Asian and White adults, but the benefit for Black adults remains unclear due to small study numbers.
Liraglutide reduces OSA severity in patients with COPD and obesity in exploratory analysis
Could a weight loss drug help people with COPD breathe easier at night?
A secondary exploratory analysis of a 40-week RCT in 40 patients with COPD and overweight/obesity found liraglutide (3.0 mg) significantly r…
A weight loss drug reduced breathing pauses and oxygen drops for people with COPD and sleep apnea, improving general health while day-time s…
Phase II RCT: Amiloride reduces arterial stiffness and blood pressure in adults with obesity and metabolic syndrome
Low-dose amiloride reduced arterial stiffness and blood pressure in adults with obesity
A phase II, single-center RCT of 137 adults with overweight/obesity and metabolic syndrome features found 24 weeks of low-dose amiloride (5 …
Low-dose amiloride reduced arterial stiffness and blood pressure in adults with obesity, offering a potential new tool to improve heart heal…
HIIT plus Spirulina supplementation alters inflammatory biomarkers in young men with obesity
Can exercise and algae supplements change inflammation in men with obesity?
A 12-week RCT in 64 young men with obesity found that combining HIIT with Spirulina supplementation increased IL-10 and ApoM while decreasin…
Combining high-intensity exercise with a daily blue-green algae supplement produced the strongest drop in inflammation markers among young m…
Phase 1b trial of oral GLP-1 agonist HDM1002 shows weight reduction in Chinese adults with overweight/obesity
Can a new pill help with weight loss? Early trial shows promise.
A phase 1b randomized controlled trial in Chinese adults with overweight/obesity without diabetes found greater weight reductions with oral …
A new oral weight-loss pill helped adults lose about 6 kilograms in just 28 days, showing early promise compared to a placebo.
Primary care clinicians report readiness for GLP-1 obesity care but note gaps in behavioral intervention competence.
Do your doctors feel ready to help you with obesity now that new treatments are available?
This early-phase survey assessed the competence, attitudes, and confidence of 276 primary care clinicians regarding obesity management. Resu…
Doctors feel ready to treat obesity with new drugs, yet admit their skills in lifestyle advice and ongoing support still fall short of what …