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Oncology
Meta-analysis
Meta-analysis finds no link between psychosocial factors and most cancer risks
Study links some psychosocial factors to higher lung cancer risk in large data review
This individual-participant data meta-analysis of 22 cohorts (N=421,799) found no association between psychosocial factors and overall cance…
Low social support, being single, or experiencing a loss are linked to higher lung cancer risk, but lifestyle factors like smoking may expla…
Apr 9, 2026
Urology
RCT
PET-guided radiation dose escalation linked to improved event-free survival in prostate cancer recurrence
Can more targeted radiation help men whose prostate cancer returns after surgery?
In this randomized trial of 140 men with biochemical progression after prostatectomy, radiation therapy dose escalation guided by either [F]…
Using advanced PET scans to guide stronger radiation helped 87% of men with returning prostate cancer stay event-free after two years.
Apr 9, 2026
Oncology
Higher county-level socio-behavioral risk associated with increased breast and prostate cancer mortality in U.S. counties.
County social factors linked to higher breast and prostate cancer death rates within racial groups
This cross-sectional review analyzed 3,141 U.S. counties stratified by race and ethnicity to examine associations between socio-behavioral d…
County-level social factors like education and housing link to higher breast and prostate cancer death rates within all racial groups studie…
medRxiv
Apr 9, 2026
Urology
RCT
Targeted plus perilesional biopsy noninferior to combined biopsy for prostate cancer detection
Could a simpler prostate biopsy find dangerous cancers just as well?
A single-center RCT in 380 biopsy-naïve patients with a single unilateral suspicious MRI lesion found targeted plus perilesional biopsy (TPL…
A simpler prostate biopsy found dangerous cancers just as well as the standard method while causing less pain and bleeding for men with susp…
Apr 6, 2026
Oncology
RCT
Lu-PSMA-617 reduces disease progression versus deferred ADT in oligometastatic HSPC in phase 2 trial
Can a targeted radiation drug delay prostate cancer progression without hormone therapy?
A phase 2 randomized controlled trial of 58 men with biochemically recurrent oligometastatic hormone-sensitive prostate cancer found Lu-PSMA…
A targeted radiation drug delayed prostate cancer progression by 20 months in early-stage patients without requiring hormone therapy first.
Apr 6, 2026
Urology
Meta-analysis
Prior HoLEP association with longer operative time and catheter duration in subsequent RARP
Does prior prostate surgery make your next operation harder or riskier?
This systematic review and meta-analysis of three retrospective studies compared men undergoing robot-assisted radical prostatectomy (RARP) …
Prior prostate surgery makes the next operation take longer and requires more rebuilding, but cancer removal and recovery remain just as eff…
Apr 6, 2026
Psychiatry
RCT
Animated video reduces pain and improves satisfaction during transperineal prostate biopsy in RCT
Animated video information reduced pain and improved satisfaction during prostate biopsy
In a randomized trial of 103 men undergoing transperineal prostate biopsy under local anesthesia, adding an animated video to standard infor…
Watching a short animated video before a prostate biopsy significantly reduced pain and improved satisfaction for men undergoing the procedu…
Apr 6, 2026
Urology
Phase II
Phase 2 trial of muscadine grape extract added to ADT for recurrent prostate cancer fatigue
Muscadine grape extract studied for fatigue in men with recurrent prostate cancer
A Phase 2 randomized controlled trial enrolled 106 men with recurrent prostate cancer on androgen deprivation therapy to test muscadine grap…
Men with recurrent prostate cancer taking hormone therapy may feel less extreme fatigue when adding a natural muscadine grape extract supple…
CT.gov
Apr 4, 2026
Genetics & Precision Medicine
Phase II
Qualitative study finds knowledge gaps and insurance concerns about prostate cancer genetic testing
What stops men from getting genetic testing for prostate cancer?
A qualitative and survey study of 20 men with prostate cancer, plus patients, carers, and healthcare providers, found generally low knowledg…
Fear of insurance discrimination and low knowledge about genetic testing are stopping many men from getting prostate cancer tests that could…
medRxiv
Apr 3, 2026
Diabetes & Endocrinology
Cohort
Chinese study develops nomogram for prostate cancer prediction in men with PSA 4-20 ng/mL
Study develops tool to predict prostate cancer risk using blood tests and imaging
A retrospective cohort study of 314 Chinese patients undergoing prostate biopsy developed a nomogram incorporating triglycerides, PI-RADS sc…
A new scoring tool combines blood tests and MRI scans to predict prostate cancer risk in men with moderately elevated PSA levels.
Frontiers
Apr 3, 2026
Urology
Sys. Review
Expert panel agrees on early detection and ARPI/ADT role for high-risk prostate cancer BCR
Experts agree on some approaches for high-risk prostate cancer recurrence but disagree on timing
An expert opinion review summarized panel discussions on managing high-risk biochemical recurrence in prostate cancer. The panel reached agr…
Experts agree on early detection and medication use for high-risk prostate cancer recurrence but disagree on the best timing for starting tr…
Frontiers
Apr 3, 2026
Urology
Cohort
Transperineal prostate biopsy shows lower infection risk with comparable cancer detection to transrectal approach
Study compares two prostate biopsy methods, finds similar cancer detection with fewer infections
A retrospective cohort study of 139 men with suspected prostate cancer at a Moroccan tertiary center found transperineal biopsy yielded long…
A safer prostate biopsy method through the skin detects cancer just as well as the standard rectal approach while causing far fewer infectio…
Frontiers
Apr 3, 2026