Pretreatment sTNFR1 and infection predict transplant-associated thrombotic microangiopathy in severe aplastic anemia
A simple blood test may flag a deadly transplant complication before it starts
This prospective nested case–control study evaluated patients with severe aplastic anemia undergoing allogeneic hematopoietic stem cell tran…
A blood marker measured before transplant may flag a deadly complication in severe aplastic anemia patients.
Systematic review and meta-analysis shows dapagliflozin increases hemoglobin in chronic kidney disease patients
Common Diabetes Drug May Help Anemia in Kidney Disease
This systematic review and meta-analysis evaluated dapagliflozin in chronic kidney disease (CKD) patients with anemia.
This study suggests a common diabetes drug could treat anemia in kidney patients without the risks of current options.
Eltrombopag monotherapy assessed in moderate aplastic anemia and unilineage bone marrow failure disorders
Oral Drug May Reduce Need for Frequent Blood Transfusions
This Phase 2 trial evaluated eltrombopag by mouth once a day in 34 people at least 2 years of age with moderate aplastic anemia or unilineag…
A new oral medication offers hope for patients who rely on regular blood transfusions.
Cross-Sectional Analysis of Cardiac Structure and Function in 57 Adults With Sickle Cell Disease
Heart Risk Found in Young Sickle Cell Patients
This observational, cross-sectional study assessed echocardiographic profiles in 57 adults with confirmed Sickle Cell Disease at a tertiary …
Young adults with sickle cell disease often show early signs of heart strain, explaining why some feel tired or short of breath even when ot…
Hematocrit–albumin gap linked to sepsis risk in ICU adults in retrospective analysis
Does a simple blood number predict sepsis risk in ICU patients?
A retrospective cross-sectional analysis of 19,134 adults with first ICU admissions found that a higher hematocrit–albumin gap (HAG) was ass…
A simple blood number called the hematocrit–albumin gap predicts sepsis risk in ICU patients, with higher levels increasing infection odds b…
Scoping review identifies poor health outcomes in children under seven with care experience in high-income countries
Young Children in Care Face Hidden Health Risks
This scoping review synthesizes evidence from 36 articles regarding children under seven years in high-income countries with care experience…
Young children in foster or kinship care face hidden physical health risks like poor growth, dental problems, and low vaccination rates befo…
POCUS-guided assessments and serial exchange transfusions improved outcomes in a 20-year-old male with sickle cell disease and acute chest syndrome
Bedside Ultrasound Saves Sickle Cell Lives
This single case report describes a 20-year-old male with HbSS, acute chest syndrome, and acute pulmonary hypertension managed in the ICU.
A simple ultrasound at the bedside can tell doctors exactly when a sickle cell patient needs another blood transfusion to save their life.
Total IgG Concentration Linked to Anemia in Hemodialysis Patients
Is low immunity linked to anemia in dialysis patients, or just age?
This cross-sectional study included 351 participants, comprising 179 dialysis patients and 172 healthy controls.
Dialysis patients with weaker overall immune defenses are more likely to have anemia, while protection from chickenpox offers little clue ab…
Video capsule endoscopy in children shows diagnostic yield for Crohn's disease but requires endoscopic placement
Tiny Camera Spots Crohn's Damage That Scans Miss in Kids
A retrospective single-center study of 60 children undergoing 76 VCE examinations found VCE supported new Crohn's diagnosis in 46% of cases …
A tiny swallowed camera found gut inflammation missed by standard scans in children with Crohn's disease, changing treatment plans for more …
Renizgamglogene autotemcel infusion showed engraftment and hemoglobin increases in severe sickle cell disease patients
One Gene Edit Stopped Painful Sickle Cell Crises in Most Patients
This single-group, open-label, multicenter Phase 1-2 trial enrolled 28 patients with severe sickle cell disease aged 12 to 50 years.
A single infusion of CRISPR-edited stem cells eliminated painful sickle cell crises in 27 out of 28 patients by switching the body back to p…
Proteogenomic analysis in sickle cell disease identifies 560 pQTL and prioritizes five proteins for HbF investigation
Study maps genetic links to blood proteins in sickle cell disease patients
An observational proteogenomic analysis of 343 sickle cell disease (SCD) patients identified 560 protein quantitative trait loci (pQTL), inc…
A study of sickle cell disease patients identified 560 genetic links to blood proteins, including 58 new ones, with five proteins potentiall…
Delayed consultation and sickle cell disease associated with poor outcomes in pediatric osteomyelitis in Cameroon
Study in Cameroon finds delayed care linked to worse bone infection outcomes in children
A retrospective cross-sectional study of children with hematogenous osteomyelitis at five referral hospitals in Douala, Cameroon, found dela…
Children in Cameroon who waited over three months for care faced much higher risks of chronic infections, lasting problems, and long antibio…
Questions about Anemia
Does taking iron powders for five months help children with malaria-induced anaemia?
Taking iron powders for five months helps children with malaria-induced anaemia by raising haemoglobin levels, but it does not improve growth measurements like height or weight.
Full answer →Do erythropoiesis-stimulating agents help adults with heart failure and anaemia?
ESAs reduce total heart failure hospitalizations and improve hemoglobin and exercise tolerance, but do not lower first hospitalization or mortality risk.
Full answer →How common is anemia among pregnant women who participate in the WIC program?
Anemia among pregnant WIC participants increased from 10.1% in 2008 to 11.4% in 2018, with higher rates in Black women and later trimesters.
Full answer →