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Community-Acquired Pneumonia

Part of Pneumonia

Subtypes of Community-Acquired Pneumonia

Community-acquired bacterial pneumonia 1 Mycoplasma pneumoniae CAP 1

14 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Community-Acquired Pneumonia

12 trials tracked for Community-Acquired Pneumonia: 3 in phase 3 or 4 and 2 with published results. The most-cited published study has 142 citations.

12Trials tracked
3Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 3 3 Phase 2 1 Phase 1 2 Other / NA 6
  1. Phase 3 Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With Pneumonia Completed · 142 cited
  2. Phase 3 Study to Compare Lefamulin to Moxifloxacin for the Treatment of Adults With Pneumonia Completed · 108 cited
  3. Phase 3 Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial Pneumonia Completed
  4. Phase 2 A Phase 1b/2a Study of the Safety and Pharmacokinetics of Rhu-plasma Gelsolin in Hospitalized Subjects With CAP Completed
  5. Phase 1 Study to Evaluate the PK of PO Omadacycline in Adults With Community-Acquired Bacterial Pneumonia Completed
  6. Phase 1 Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia Completed
Show 6 more trials
  1. N/A Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries Completed
  2. N/A Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Pneumonia and Pneumococcal Vaccine Completed
  3. N/A Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions Completed
  4. N/A Evaluation of the Treatment With Klacid®SR in Patients With Lower Respiratory Tract Infection Completed
  5. N/A Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin Completed
  6. N/A Improving Pneumococcal Vaccination Rates in an Ambulatory Pre-surgical Testing Setting Completed

Showing the 12 most-cited and recently-updated of 12 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Pneumonia

Related studies from across the Pneumonia family.

Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia
Infectious Disease Meta-analysis
Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia Inhaled antibiotics help cure pneumonia and lower death risk in ICU patients
This systematic review and meta-analysis of adjunctive inhaled antibiotics for ventilator-associated pneumonia found significantly improved …
Adding inhaled antibiotics to standard care improved cure rates and reduced death in patients with ventilator-associated pneumonia.
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
Rheumatology Sys. Review
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia Non-invasive ventilation may help patients with Madelung's disease and respiratory failure
This case series describes non-invasive ventilation using a total face mask in two patients with Madelung's disease who experienced acute re…
A small case series suggests non-invasive ventilation can manage acute respiratory failure in patients with Madelung's disease, though more …
Systematic review maps 50 most-cited articles on pediatric respiratory infections
Pediatrics Sys. Review
Systematic review maps 50 most-cited articles on pediatric respiratory infections Most cited research on child respiratory infections comes from US, China, Canada
This systematic bibliometric review analyzed the 50 most-cited articles on pediatric respiratory infections. Key findings show a predominanc…
A review of 50 top-cited articles on pediatric respiratory infections shows most research comes from just three countries.
TCM injections plus conventional medicine show promise for viral pneumonia
Drug Pipeline Meta-analysis
TCM injections plus conventional medicine show promise for viral pneumonia Seven Chinese Medicine Injections Compared for Viral Pneumonia Recovery
A network meta-analysis of 8,678 patients found that specific TCM injections combined with conventional medicine improved outcomes like coug…
A large review of 8,678 patients found that adding a Chinese medicine injection called Reduning to standard care may help people with viral …
Systematic review and meta-analysis of pneumonia prevalence and antimicrobial resistance in Ghana
Infectious Disease Meta-analysis
Systematic review and meta-analysis of pneumonia prevalence and antimicrobial resistance in Ghana Ghana's pneumonia rate hits 22 percent with one region most at risk
This systematic review and meta-analysis synthesizes data on pneumonia prevalence and antimicrobial resistance patterns among participants i…
A new review finds 22 percent of Ghanaians have pneumonia, with children under 5 especially vulnerable and widespread resistance to common a…
Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology
Pulmonology & Critical Care Sys. Review
Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology Choosing the right ultrasound probe can improve lung diagnoses for dogs and cats
This evidence-based review examines transducer selection for lung ultrasound in dogs and cats with pulmonary pathology.
Veterinary lung ultrasound accuracy depends on probe choice. This review highlights how transducer selection affects diagnosis in emergency …
Meta-analysis shows integrated nursing interventions improve outcomes in paediatric severe pneumonia
Pediatrics Meta-analysis
Meta-analysis shows integrated nursing interventions improve outcomes in paediatric severe pneumonia Integrated nursing care improves severe pneumonia in children
This meta-analysis reviews six studies conducted in paediatric intensive care units involving paediatric patients with severe pneumonia.
A review of six studies finds that integrated nursing care helps children with severe pneumonia recover faster, with less fever and shorter …
Shorter antibiotic courses may match longer ones for canine pneumonia, but evidence is weak
Infectious Disease Meta-analysis
Shorter antibiotic courses may match longer ones for canine pneumonia, but evidence is weak Shorter antibiotic courses work just as well as longer ones for dog pneumonia
This systematic review and meta-analysis of 74 dogs found no significant difference in treatment success between shorter (10-14 days) and lo…
A new analysis suggests shorter antibiotic courses may treat dog pneumonia just as well as longer ones, though evidence for cats is missing.
Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
Pediatrics Cohort
Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity Testing for resistance genes may guide antibiotic choices
This retrospective cohort study of 150 children with Mycoplasma pneumoniae pneumonia evaluated resistance gene expression and antibiotic man…
New evidence suggests that checking for resistance genes in children with pneumonia could help doctors decide when to switch antibiotics.
Pulmonary barotrauma incidence and risk factors in non-HIV PCP patients
Pulmonology & Critical Care Cohort
Pulmonary barotrauma incidence and risk factors in non-HIV PCP patients Researchers find oxygen ratio predicts lung injury in pneumonia patients
This single-center retrospective cohort study of 334 non-HIV patients with Pneumocystis jirovecii pneumonia found that 12.0% developed pulmo…
A new model helps identify pneumonia patients at higher risk for severe lung complications using oxygen levels and blood markers.
Retrospective analysis of Systemic Inflammatory Response Index in elderly influenza A pneumonia
Rheumatology Cohort
Retrospective analysis of Systemic Inflammatory Response Index in elderly influenza A pneumonia New Blood Test Predicts Flu Severity in Older Adults
This retrospective analysis evaluated the Systemic Inflammatory Response Index in 160 patients aged 65 years or older with influenza A virus…
A new blood test using white blood cell counts may help doctors predict flu pneumonia severity in older adults before symptoms worsen.
Modified thin-slab volume rendering improves diagnostic performance for pneumonic-type lung cancer and inflammatory pneumonia
Oncology Cohort
Modified thin-slab volume rendering improves diagnostic performance for pneumonic-type lung cancer and inflammatory pneumonia New Imaging Trick Tells Cancer and Pneumonia Apart
This retrospective cohort study evaluated modified thin-slab volume rendering (tsVR) with densitometry-derived thresholds against convention…
Doctors can now tell aggressive lung cancer apart from pneumonia more accurately using a simple tweak to CT scans that highlights subtle dif…

Questions about Community-Acquired Pneumonia

What are the risks of co-infection in children with HMPV and severe community-acquired pneumonia?

Co-infection, especially with Mycoplasma pneumoniae, is a significant risk factor for severe CAP in children with HMPV, with studies showing higher rates of co-infection in severe cases.

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Are children with severe community-acquired pneumonia more likely to have Mycoplasma pneumoniae?

Yes, children with severe community-acquired pneumonia are more likely to have Mycoplasma pneumoniae, with studies showing higher detection rates in severe cases.

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Can machine learning predict mortality better than APACHE-II for severe community-acquired pneumonia?

Yes, machine learning models, particularly GBDT and XGBoost, have outperformed APACHE-II in predicting mortality for severe community-acquired pneumonia with respiratory failure.

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What is the severe community-acquired pneumonia rate for children with HMPV?

In a recent study of hospitalized children with HMPV, 28.0% had severe community-acquired pneumonia (CAP).

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How does the severity of community-acquired pneumonia affect the detection of Mycoplasma pneumoniae in children?

Severe community-acquired pneumonia in children is associated with higher detection rates of Mycoplasma pneumoniae compared to non-severe cases, likely due to higher bacterial load and immune response.

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Does amoxicillin work just as well as other antibiotics for community-acquired pneumonia?

Current evidence suggests amoxicillin is generally as effective as other antibiotics for community-acquired pneumonia, but the choice depends on local resistance patterns and patient factors.

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See all 6 questions about Community-Acquired Pneumonia →