Serum N-myc and STAT interactor (NMI) levels predict 30-day mortality and septic shock in adult sepsis patients
New Blood Marker Spots Deadly Sepsis Early
This cohort study of 399 adult patients diagnosed with sepsis evaluated serum N-myc and STAT interactor (NMI) concentrations.
A newly studied blood protein can spot which sepsis patients are most at risk — long before their condition crashes.
Narrative review discusses natural bioactive compounds in sepsis with noted pharmacokinetic and safety limitations
Natural compounds may protect organs in sepsis, but delivery remains a major hurdle
This narrative review examines natural bioactive compounds, including flavonoids, terpenoids, alkaloids, and quinones, regarding their poten…
A review suggests natural chemicals could shield vital organs during sepsis, yet getting them into the body safely is the real challenge.
Elevated pre-sepsis vitamin B12 levels associated with increased 90-day mortality in adults with sepsis
High Vitamin B12 Before Sepsis Linked to Higher Death Risk
This retrospective cohort study analyzed 37,660 adults diagnosed with sepsis using the TriNetX database.
If your vitamin B12 level is high before you get sepsis, your risk of dying from it may be significantly higher.
Gut Microbiota Dysbiosis Linked to Sepsis in Infants and Young Children With Severe Pneumonia
Gut Bacteria May Predict Sepsis in Sick Babies
This prospective, 1:1 matched case-control study included 100 infants and young children (28 days–36 months) in the PICU.
A 6-month-old baby fights to breathe in a hospital bed.
Dataset describes continuous monitoring in premature VLBW infants across four US NICUs
Heart rate and oxygen data tracked in premature infants
This dataset description covers continuous heart rate and oxygen saturation monitoring in 3,829 premature very low birth weight infants acro…
A new dataset tracks continuous heart rate and oxygen levels in 3,829 premature infants to improve care.
Retrospective cohort study links pulse pressure levels to 28-day mortality in septic shock patients
New Blood Pressure Target Could Save Septic Shock Patients
This retrospective cohort study examined septic shock patients across two settings to assess pulse pressure levels during the first 24 h in …
A new study suggests a specific blood pressure range improves survival for people in septic shock.
Sterile-site yeast isolates linked to fungemia, sepsis, and mortality in a retrospective cohort study
Blood Infections From Yeast Are Changing—Here’s What Patients Need to Know
This retrospective cohort study analyzed 231 consecutive sterile-site yeast isolates from Nanjing Drum Tower Hospital between 2019 and 2023.
This study shows that not all yeast infections are the same, and your specific risk factors—like kidney injury or recent surgery—can dramati…
Meta-analysis of 34 Studies Shows Buffered Solutions Do Not Lower Mortality Compared to 0.9% Saline
Saline vs. Balanced Fluids: What ICU Patients Really Need
This systematic review and meta-analysis of 34 studies involving 37,859 participants evaluated buffered solutions versus 0.9% saline in crit…
A major review finds no survival benefit for balanced IV fluids over standard saline in ICU patients, though kidney effects remain unclear.
Prospective observational study of inflammatory mediators in adult ED patients with suspected infection
Blood protein patterns in sick ER patients hint at who might survive
This primary prospective, observational study in a single-centre Emergency Department measured longitudinal inflammatory mediators in 173 ad…
In ER patients with suspected infection, certain blood proteins changed over time and linked to survival, offering clues for future monitori…
Meta-analysis finds preadmission metformin use associated with reduced mortality in diabetic sepsis patients
Metformin Linked to Lower Sepsis Death Risk
This systematic review and meta-analysis of 14 studies (12,687 patients) examined preadmission metformin use in diabetic sepsis patients.
Diabetic patients taking metformin before sepsis face nearly 40% lower death risk, suggesting this common pill may quietly boost survival du…
Systematic review proposes S100A8/A9–NETosis feedback loop as core sepsis mechanism
Sepsis May Have a Hidden Engine Driving Death
This systematic review synthesizes evidence on sepsis, proposing the S100A8/A9–NETosis positive feedback loop as a core pathological mechani…
A dangerous cycle between immune cells and blood clots may be the hidden engine driving sepsis death, offering new ways to stop organ failur…
Pooled analysis review of rezafungin versus caspofungin for candidemia and invasive candidiasis
Weekly Drug Clears Blood Fungus Faster Than Daily Treatment
This review synthesizes a pooled analysis of two randomized trials evaluating rezafungin versus caspofungin in adults with candidemia or inv…
A new weekly medication clears blood infections just as well as daily shots, offering hope for shorter care.