Hematocrit–albumin gap linked to sepsis risk in ICU adults in retrospective analysis
Does a simple blood number predict sepsis risk in ICU patients?
A retrospective cross-sectional analysis of 19,134 adults with first ICU admissions found that a higher hematocrit–albumin gap (HAG) was ass…
A simple blood number called the hematocrit–albumin gap predicts sepsis risk in ICU patients, with higher levels increasing infection odds b…
Seraph Microbind filter used in a 7-year-old with refractory septic shock and invasive Streptococcus pyogenes infection
New Filter May Save Children in Life-Threatening Shock
This single case report describes a previously healthy 7-year-old girl with refractory septic shock and invasive Streptococcus pyogenes infe…
This device offers a new rescue option for kids whose bodies shut down from infection.
Narrative review on sepsis and the microbiome, highlighting unresolved causality and variability
Could your sepsis treatment be missing a key clue about your unique biology?
This narrative review synthesizes current evidence on the microbiome in sepsis.
Sepsis treatment risks vary by biology because gut bacteria and genes drive inflammation, yet doctors currently lack tools to predict who wi…
Insulin administration associated with lower 28-day mortality in non-diabetic sepsis patients
Insulin Might Help Sepsis Patients Survive Longer
This retrospective cohort study of 11,289 non-diabetic patients with sepsis found insulin administration was associated with reduced 28-day …
Insulin therapy was linked to a 37% lower risk of death in non-diabetic sepsis patients, though it extended hospital stays.
7-Day Antibiotic Regimen Non-Inferior to 14-Day for Uncomplicated Neonatal Sepsis in RCT
Can shorter antibiotics cure newborn sepsis just as well as two weeks of treatment?
This randomized control assessor-blinded trial evaluated 140 neonates weighing ≥ 1000 g with culture-positive sepsis in a tertiary Neonatal …
A 7-day antibiotic course for newborn sepsis worked as well as 14 days, with babies leaving the hospital sooner and needing less breathing s…
CAR T-cell therapy linked to endocrine adverse events in FAERS analysis
CAR T-cell therapy may trigger rare but serious hormone problems like adrenal failure
A retrospective disproportionality analysis and literature review of 269 endocrine adverse event reports from the FAERS database (2017 to Q2…
CAR T-cell therapy can trigger rare but serious hormone problems like adrenal failure, and death risk rises when these issues occur with sev…
Corticosteroids reduce short-term and long-term mortality in adult sepsis patients according to a systematic review
What Doctors Give Sepsis Patients Is Finally Getting Clearer
This systematic review and network meta-analysis evaluated corticosteroids, specifically hydrocortisone and hydrocortisone plus fludrocortis…
Corticosteroids cut short-term and long-term sepsis death risk for ICU adults in large review, though doctors still need clearer guidance on…
Biomarkers and clinical factors show statistical associations with sepsis-induced coagulopathy in 37,459 patients
Your Blood May Signal a Deadly Clotting Crisis Before It Strikes
This systematic review and meta-analysis evaluated 37,459 patients to assess the association between various biomarkers and clinical factors…
Blood markers like glycocalyx degradation and low fibrinogen can predict deadly clotting in sepsis patients early, potentially saving lives …
AMR strategies in LMIC newborns reduce antibiotic use and mortality in meta-analysis
Strategies to reduce antibiotic resistance may lower infection risks in newborns in low-income countries
A systematic review and meta-analysis of 31 facility-based studies in LMICs found that strategies to reduce antimicrobial resistance, includ…
Strategies to curb antibiotic resistance in newborns in low-income countries lower infection risks and reduce overall mortality.
Thiamin supplementation associated with reduced mortality in septic shock patients
Thiamin Cuts Death Risk in Sepsis Shock
This meta-analysis of randomized controlled trials evaluated thiamin supplementation versus placebo or blank controls in patients with septi…
A common vitamin called thiamin lowers death risk and kidney failure needs for patients in septic shock, offering new hope for severe infect…
Protein nutritional support in critically ill adults shows heterogeneous mortality benefits and potential harm from very high early doses
Why ICU Patients Need More Protein, But Not Too Much
This narrative review evaluates protein supplementation strategies in critically ill adults, including those with sepsis or severe burns.
Doctors caring for patients in the ICU know protein matters for recovery, but a new review shows the right dose depends on the illness, the …
Retrospective cohort study examines MRSA prevalence and resistance patterns in nosocomial bloodstream infections among 96 patients in central China
Are hospital infections getting harder to treat, or is the data stable?
This retrospective cohort study analyzed 96 Staphylococcus aureus isolates from patients with nosocomial bloodstream infections at a tertiar…
Hospital bloodstream infections from tough MRSA bacteria stayed stable in frequency, but one patient's germ was resistant to the last-resort…