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Cardiology
RCT
In CRT recipients with persistent AF, rhythm control improved LVEF compared to rate control strategies.
Does fixing your heart rhythm actually improve pump function in this specific group?
This randomized trial evaluated rhythm versus rate control strategies in 43 CRT recipients with long-standing persistent AF and low biventri…
Fixing irregular heartbeats boosted heart muscle strength in patients with devices, but daily life and exercise ability improved similarly w…
Apr 9, 2026
Cardiology
RCT
Catheter ablation reduces cardiovascular risk in atrial fibrillation with normal left atrial diameter but not in enlarged atria
Atrial fibrillation ablation benefits vary by heart size in large trial
This randomized controlled trial evaluated 1130 patients with atrial fibrillation who underwent baseline echocardiographic measurement of le…
Patients with normal-sized hearts gain the most life-saving benefit from atrial fibrillation ablation compared to those with enlarged hearts…
Apr 6, 2026
Cardiology
Meta-analysis
Elevated soluble ST2 predicts atrial fibrillation development and recurrence after catheter ablation in 14,582 participants.
High sST2 levels linked to higher risk of atrial fibrillation and recurrence
This systematic review and meta-analysis of 19 studies involving 14,582 participants examined the association between soluble ST2 (sST2) lev…
High blood levels of a protein called sST2 signal a greater risk of developing atrial fibrillation and its return after heart treatment.
Apr 6, 2026
Cardiology
RCT
Post-hoc analysis links lower systolic BP to higher cardiovascular risk in AF and stable CAD
Lower blood pressure linked to higher risk in AF patients with heart disease
A post-hoc analysis of the AFIRE trial (n=2135) found patients with atrial fibrillation and stable coronary artery disease who had baseline …
Patients with atrial fibrillation and low blood pressure face a 38% higher risk of heart attack, stroke, or death compared to those with hig…
Apr 6, 2026
Cardiology
Meta-analysis
DOACs show varied efficacy and safety profiles versus VKAs in atrial fibrillation patients with fall risk
Study compares blood thinners for atrial fibrillation patients with fall risk
A Bayesian network meta-analysis of 10 studies (5 RCTs, 5 observational) in AF patients with fall history/risk found apixaban ranked highest…
For atrial fibrillation patients at risk of falling, apixaban best prevents strokes while edoxaban best lowers major bleeding risks compared…
Apr 5, 2026
Cardiology
RCT
Left atrial appendage closure fails noninferiority test versus medical therapy in high-risk AF patients
Study finds device for stroke prevention in atrial fibrillation not as effective as medical therapy
A multicenter RCT in Germany randomized 912 high-risk AF patients to catheter-based left atrial appendage closure or physician-directed best…
A new German study found that a heart device to prevent strokes in atrial fibrillation was not as effective as standard blood-thinning medic…
Apr 4, 2026
Physical Medicine & Rehab
HIIT improves exercise capacity in cardiovascular rehabilitation for CAD, HF, and atrial fibrillation
Review suggests high-intensity interval training can help improve exercise capacity in heart patients
A rapid review and meta-analyses of cardiovascular rehabilitation programs for patients with coronary artery disease, heart failure, or atri…
High-intensity interval training may improve exercise capacity for heart patients with coronary artery disease or heart failure, according t…
medRxiv
Apr 3, 2026
Cardiology
Meta-analysis
Factor XIa inhibitors show higher stroke risk but lower bleeding risk versus DOACs in atrial fibrillation
New blood thinners cut bleeding risk but triple stroke risk in heart rhythm patients
A meta-analysis of 3 RCTs in 16,845 patients with atrial fibrillation found Factor XIa inhibitors were associated with a 3.32 times higher r…
New blood thinners for atrial fibrillation cut bleeding risk by 59% but triple the risk of stroke, raising concerns they may be too gentle t…
Apr 3, 2026
Cardiology
Meta-analysis
Catheter ablation for atrial fibrillation in cancer patients shows non-significant bleeding trend
Catheter ablation for atrial fibrillation shows similar outcomes in cancer and non-cancer patients
A meta-analysis of 69,819 patients from eight observational studies compared catheter ablation outcomes in atrial fibrillation patients with…
Catheter ablation for atrial fibrillation works similarly in cancer and non-cancer patients, with a trend toward more bleeding in cancer sur…
Apr 2, 2026
Cardiology
Meta-analysis
Machine learning shows moderate accuracy for predicting AF recurrence after catheter ablation in meta-analysis
Can AI predict if your irregular heartbeat will return after treatment?
A systematic review and meta-analysis of 17 studies found machine learning algorithms achieved a mean AUC of 0.81 for predicting atrial fibr…
Artificial intelligence can predict if an irregular heartbeat will return after treatment with an average accuracy score of 0.81, though res…
Apr 2, 2026
Cardiology
Cohort
Deep learning model predicts left atrial imaging from ECG, improves AF and HF risk stratification
Can a simple ECG reading predict your risk for heart rhythm problems?
An observational cohort study using UK Biobank data developed a deep learning model that predicts left atrial imaging indices from 12-lead E…
A routine 10-second heart test can now predict hidden risks for serious heart conditions better than current clinical scores.
medRxiv
Apr 2, 2026
Cardiology
Cohort
Higher prognostic nutritional index associated with lower MACE and mortality in AF and HFpEF patients
Study links better nutritional scores to lower heart risks in patients with two heart conditions
A retrospective cohort study of 734 patients with atrial fibrillation and HFpEF found that higher prognostic nutritional index (PNI) was ind…
Patients with better nutrition scores face a 63% lower risk of heart events and an 83% lower risk of death compared to those with poorer sco…
Frontiers
Apr 2, 2026