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Radiology & Imaging
Cohort
CT-SMA improves trabecular estimation and OA diagnosis in knee osteoarthritis cohorts.
The Hidden Bone Problem
This cohort study evaluated a CT-based Subchondral Microstructural Analysis (CT-SMA) method utilizing distillation learning technology in a …
A new method lets routine knee CT scans reveal hidden bone damage that usually requires expensive, hard-to-get MRI appointments.
Frontiers
Apr 10, 2026
Diabetes & Endocrinology
RCT
Calorie restriction plus exercise reduced IL-6 and knee pain more than diet alone in knee OA
Small study finds adding exercise to calorie restriction may reduce knee pain and inflammation
A 4-week RCT in 23 overweight/obese adults with knee osteoarthritis compared calorie restriction alone to restriction plus aerobic exercise.…
Adding exercise to a calorie-reduced diet lowered knee pain and a specific inflammation marker in overweight people with knee osteoarthritis…
Apr 8, 2026
Radiology & Imaging
Cohort
Deep learning reconstruction improves 5.0 Tesla knee MRI quality and diagnostic agreement in 69-patient cohort
Deep learning algorithm improves knee MRI image quality in small study
A prospective cohort study of 69 patients undergoing knee arthroscopy and 5.0 Tesla MRI found that deep learning-based reconstruction (DLR) …
A computer program using deep learning improved knee MRI image clarity by up to 350% compared to standard scans in a small study.
Frontiers
Apr 3, 2026
Radiology & Imaging
RCT
IPFP preservation versus resection in TKA shows no significant difference in 12-month KOOS scores
Study finds no clear benefit to preserving or removing knee fat pad during joint replacement
This RCT in patients undergoing TKA for knee osteoarthritis found no statistically significant difference in 12-month KOOS score improvement…
Whether to keep or remove the fat pad under your kneecap during knee replacement surgery makes no difference to your recovery or pain relief…
NEJM Evid
Apr 2, 2026
Anesthesiology & Pain Medicine
RCT
Pain catastrophizing predicts tDCS response patterns in knee osteoarthritis pain
Why does brain stimulation help some knee pain patients but not others?
A secondary analysis of 60 participants with knee osteoarthritis from a randomized trial used machine learning to identify predictors of res…
Knee pain patients who fear their pain the most often fail to benefit from brain stimulation therapy, while those with lower initial pain le…
Apr 2, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Mobilization with movement reduces pain and disability in knee osteoarthritis meta-analysis
Mobilization therapy shows promise for reducing knee osteoarthritis pain and disability
A meta-analysis of 2 RCTs in individuals with knee osteoarthritis found mobilization with movement (MWM) significantly reduced pain (Hedges'…
A hands-on therapy called mobilization with movement significantly reduced pain and improved daily function for people with knee osteoarthri…
Apr 2, 2026
Geriatrics & Aging
RCT
Sarcopenic obesity prevalence is 28% in adults with advanced knee OA and severe obesity
Sarcopenic obesity found in 28% of adults with severe knee osteoarthritis and obesity
A cross-sectional baseline analysis of a pilot RCT (n=50) found sarcopenic obesity prevalence was 28% among adults with advanced knee OA and…
Nearly one-third of adults with severe knee arthritis and obesity have low muscle mass, leading to worse walking distance, function, and qua…
Apr 2, 2026