Research across Cancer
Related studies from across the Cancer family.
Questions about leukemia
Can perinatal factors increase the risk of childhood acute leukemia?
Research shows that high birth weight, maternal diabetes, hypertension, history of abortion, and cesarean sections are linked to a higher risk of childhood acute leukemia.
Full answer →How does a prehabilitation program help leukemia patients before chemotherapy starts?
A prehabilitation program combining exercise, nutrition, and psychological care helps leukemia patients before chemotherapy by improving walking distance, reducing fatigue, and lowering anxiety and depression.
Full answer →All leukemia Articles
- AZA or LDAC combined with venetoclax likely improves mortality, remission, and quality of life
- 7-day venetoclax with intensive chemotherapy achieves 90.3% composite complete remission in AML
- Novel strategies aim to separate GVHD from GVL effects in allo-HCT for AML
- Rate of drug concentration rise alters hemodynamic responses and mortality risk in coronary heart disease patients
- Fertility preservation in female leukemia patients carries risks of leukemic cell contamination and disease reintroduction
- Antibody-based therapies offer potential efficacy and durability options for relapsed refractory acute myeloid leukemia patients
- HMA-venetoclax yields 50% overall response rate in relapsed/refractory AML meta-analysis
- Xatmep receives FDA approval for pediatric acute lymphoblastic leukemia and polyarticular juvenile idiopathic arthritis
- Reduced-intensity ATRA plus arsenic with GO or low-dose anthracycline improves event-free survival in high-risk APL
- Review of glycolytic metabolism in acute myeloid leukemia cells notes research scope and limitations
- Narrative review suggests idiotype-directed CAAR-T therapy remains hypothetical for B-cell malignancies
- Scoping review examines imatinib gonadotoxicity in males with chronic myeloid leukemia or gastrointestinal stromal tumors
- Case report and review: azacytidine plus ruxolitinib in connective tissue disease with CMML and myelofibrosis
- Network Meta-Analysis Compares FLT3 Inhibitors in Acute Myeloid Leukemia
- Case report and review of TTMV::RARA-positive APL with spinal cord compression in a child
- Genetic variants in ABCB1 and ABCG2 raise imatinib trough levels in CML patients
- Combining pegylated interferon with nilotinib improves early molecular response in newly diagnosed chronic phase chronic myeloid leukaemia
- Meta-analysis finds fluoroquinolone prophylaxis reduces febrile neutropenia in pediatric ALL
- Systematic review and meta-analysis finds high prevalence of ocular manifestations in leukemia patients
- Lyophilized pegaspargase shows similar activity to liquid form in pediatric ALL
- Meta-analysis links perinatal factors to childhood acute leukemia risk
- Meta-analysis links maternal infection in pregnancy to childhood ALL risk
- Review of observational data on non-sedated MRI feasibility in newly diagnosed ALL patients ages 3 to 10 years
- CPX-351 improves survival in AML with myelodysplasia-related changes
- Case report describes myeloid sarcoma relapse in breast after nasal cavity presentation
- Zanubrutinib associated with higher 3-year PFS versus acalabrutinib-venetoclax in treatment-naive CLL
- CPX-351 first-line therapy shows 61% overall response in therapy-related AML or AML with myelodysplastic-related changes
- Case report on asciminib plus ponatinib or axitinib in CML relapse with B lymphoblastic blast crisis
- Narrative review on gamma delta T cell therapies for hematologic malignancies and immune cytopenias
- Donor-derived anti-CD33 CAR T-cell therapy showed 20% overall response in 15 adults with relapsed AML/MDS
- Meta-analysis identifies new genetic loci linked to acute myeloid leukemia risk in 4710 cases
- Meta-analysis links DNA repair gene polymorphisms to leukemia risk across 54 studies
- High prevalence and multidrug resistance of gram-negative bloodstream infections in children with acute myeloid leukemia
- Decitabine versus hydroxyurea in advanced chronic myelomonocytic leukemia shows survival differences linked to baseline counts
- FDA Approves Danziten (nilotinib) for Adult Patients with Newly Diagnosed or Resistant/Intolerant Ph+ CML
- FDA Approves Vanflyta (quizartinib) for Newly Diagnosed FLT3-ITD-Positive AML in Adults
- Review of observational data on vaccine antibody levels in children with acute lymphoblastic leukemia
- Review of ATRA and ATO induction therapy in acute promyelocytic leukemia with RNA sequencing insights
- Case report and literature review on concurrent t-AML and LNTB treated with chemoimmunotherapy
- Case report of ATRA and VAH regimen in refractory EVI1-positive AML
- Reiki reduced pain and improved quality of life in hospitalized children with leukemia aged 5-7
- Registry-based systematic review maps non-pharmacological cancer trials in Africa
- Narrative review explores immune monitoring for relapse prediction after AML stem cell transplant
- Prehabilitation program improves physical and psychological outcomes in leukemia patients before chemotherapy
- Pediatric ALL outcomes at Muhimbili National Hospital show 72% 12-month survival with no significant differences by demographic or care pathway factors
- Ibrutinib monotherapy showed durable progression-free survival in patients with TP53 aberrations or advanced age
- Itacitinib plus standard therapy in acute leukemia or myelofibrosis patients undergoing reduced-intensity conditioning donor stem cell transplantation
- Red blood cell parameters predict sepsis in children with ALL and chemotherapy-induced neutropenia
- Dasatinib Added to Intensive Chemotherapy Fails to Improve Survival in CBF-AML
- 6-MP mini-tablets show bioequivalence to reference tablets in fasted children with ALL
- Pivekimab sunirine shows activity in frontline and relapsed Blastic plasmacytoid dendritic cell neoplasm
- Ponatinib in CP-CML resistant to prior TKI or T315I mutation showed molecular response at Month 12
- In children with Ph+ ALL, TKI-based therapy reduced HSCT use while maintaining comparable outcomes versus Ph+ALL04
- Meta-analysis compares CAR T-cell constructs in 1540 relapsed/refractory B-ALL patients
- Phase II trial shows high remission and survival with frontline ATRA-ATO for newly diagnosed APL
- Systematic review shows increased fat mass and decreased fat-free mass in children with acute lymphoblastic leukemia during treatment
- Meta-analysis finds HMA plus venetoclax yields 66% CR/CRi rate in younger, fit AML patients
- Case report: CMML initially diagnosed as ITP in one patient, stabilized with decitabine
- Imatinib reduces TNF-α levels in CML patients; persistent levels correlate with poor response
- Case report: obinutuzumab and venetoclax associated with nephrotic syndrome resolution in two CLL patients
- Phase I/II trial tests IMRT with chemotherapy before transplant for relapsed/refractory ALL/AML
- Asciminib superior to IS-TKIs in newly diagnosed CML-CP: MMR 74.1% vs 52.0% at 96 weeks
- AI tool predicts acute leukemia subtypes with AUROC 0.94 for AML, 0.98 for promyelocytic, 0.84 for ALL in international cohort
- Phase II trial compares quizartinib vs placebo with chemotherapy in FLT3 wild-type AML