Umbrella review identifies risk factors and protective factors for male infertility and semen quality
New study lists many things that hurt male fertility and health
This umbrella review of 43 studies synthesizes evidence on risk factors for male infertility and abnormal semen parameters.
A new review shows that obesity, smoking, and certain illnesses can hurt sperm, but healthy habits might fix the problem.
Meta-analysis finds slight IQ difference in children with type 1 diabetes versus peers
Children with diabetes show slightly lower IQ scores than peers
This meta-analysis of 16 studies examined cognitive outcomes in children and adolescents with type 1 diabetes.
New research shows kids with type 1 diabetes may have slightly lower IQ scores but large groups show no reading or language gaps
Barriers and promoters to CGM and AID use in youth with T1D and public insurance
New plan helps families with public insurance get life-saving diabetes tech
This prospective, mixed-methods study examined barriers and promoters to continuous glucose monitoring (CGM) and artificial insulin delivery…
A new study reveals why families with public insurance struggle to get diabetes tech and offers a custom plan to fix it.
Beta-cell stress responses contribute to early Type 1 diabetes development and disease progression
Type 1 Diabetes May Start Inside the Cell, Not Just the Immune System
This perspective and review of human tissue, single cell transcriptomics, and longitudinal cohort studies indicates that beta-cell stress re…
This study shifts the focus of Type 1 diabetes from a pure immune problem to a two-part story where stressed cells play a key role.
FDA Approves Tzield (teplizumab) to Delay Onset of Stage 3 Type 1 Diabetes
FDA approves Tzield to delay type 1 diabetes in high-risk patients
The FDA approved Tzield (teplizumab) to delay the onset of Stage 3 type 1 diabetes in patients aged 1 year and older with Stage 2 disease.
The FDA approved Tzield (teplizumab) to delay the onset of stage 3 type 1 diabetes in people aged 1 and older with stage 2 disease.
Meta-analysis of sex differences in insulin therapy outcomes for adults with Type 1 and Type 2 diabetes
Women and Men Respond Differently to Insulin Therapy
This systematic review and meta-analysis evaluated sex differences in insulin therapy outcomes across 24 studies involving adults with Type …
Maria takes insulin every day for type 2 diabetes.
Meta-analysis of adjunctive SGLT2 inhibitors in type 1 diabetes shows mixed safety and efficacy signals
No More Bone Fear With New Diabetes Drug
This meta-analysis evaluated adjunctive SGLT2 inhibitor therapy in 6,731 patients with type 1 diabetes mellitus receiving insulin-based ther…
Many people with type 1 diabetes worry about their bones.
Systematic review and meta-analysis of integrative therapies for Type 1 Diabetes Mellitus
Yoga and Natural Therapies Help Control Type 1 Diabetes
This meta-analysis of 12 studies on integrative therapies for Type 1 Diabetes Mellitus found adjunctive benefits for glycemic control.
It’s 6 a.m. and 12-year-old Maya stirs awake.
Autoimmune Thyroiditis Prevalence Higher in Obese Women With PCOS in Retrospective Cohort Analysis
New PCOS Data Reveals Hidden Thyroid Risks
This retrospective cohort study evaluated 1,249 women with PCOS aged 18–44 years.
Women with PCOS should check their thyroid health regularly.
Machine learning model predicts in-hospital hypoglycemia in Chinese adults with type 1 diabetes
New AI Model Predicts Dangerous Blood Sugar Drops in Hospital
This retrospective cohort study of 1498 adult inpatients with type 1 diabetes in China developed a machine learning model to predict in-hosp…
This new tool could give doctors an early warning system to prevent dangerous blood sugar drops before they happen, making hospital stays sa…
Observational MRI study links impaired hypoglycemia awareness to blunted cerebral blood flow responses in type 1 diabetes
Type 1 Diabetes Rewires How the Brain Responds to Low Blood Sugar
This observational study used hyperinsulinemic clamp with arterial spin-labeling MRI to compare cerebral blood flow responses to hypoglycemi…
Type 1 diabetes changes how the brain handles low blood sugar, and those who can't feel the danger show the most severe disruption in brain …
Cadonilimab therapy in cervical cancer associated with new-onset type 1 diabetes and diabetic ketoacidosis in a case report
A Cancer Drug Triggered Sudden Diabetes in an 81-Year-Old
This systematic review includes a case report of an 81-year-old female with cervical squamous cell carcinoma who developed diabetic ketoacid…
A powerful cancer drug can switch off the body's insulin supply almost overnight, causing sudden, life-threatening diabetes in patients with…
Research across Diabetes
Related studies from across the Diabetes family.
Once-weekly basal insulin improves HbA1c by 0.09% and time in range over daily regimens
Weekly insulin offers easier management for people with type 2 diabetes
This meta-analysis of 14 randomized controlled trials involving 8,487 subjects found that once-weekly basal insulin analogs provide superior…
A new review of clinical trials shows weekly insulin can manage blood sugar as well as daily shots while reducing the number of injections.
A 6 dimension and 42 item system provides early risk assessment for high-risk diabetic feet
Experts Develop New Risk Assessment System for Diabetic Feet
This expert consultation and guideline describes the development of an early risk assessment system for high-risk diabetic feet. The consens…
A new assessment system identifies risk factors like nerve damage and circulation to help manage and prevent complications in patients with …
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
Pharmacist-led telepharmacy may improve medication adherence and reduce blood pressure in patients with NCDs
Pharmacist Led Telepharmacy May Improve Medication Adherence For Chronic Illness
This systematic review analyzed 21 trials involving 5440 participants to evaluate pharmacist-led telepharmacy for managing non-communicable …
Remote pharmacist services through phone or video may help patients with high blood pressure and diabetes stick to their daily medication pl…
Resveratrol supplementation significantly reduces LDL-C but lacks consistent impact on glycemic indices in type 2 diabetes
Resveratrol fails to improve blood sugar in type 2 diabetes
This umbrella review and meta-analysis of 10 meta-analyses evaluated resveratrol for managing type 2 diabetes. While a significant reduction…
Resveratrol supplements did not lower blood sugar or improve cholesterol in type 2 diabetes, except for a small drop in LDL cholesterol.
Pancreatic cancer involves multilayered mechanisms from environment to immune escape
Review reveals complex causes of pancreatic cancer
This narrative review synthesizes the multilayered mechanisms of pancreatic cancer, including environmental exposure, genetic susceptibility…
Pancreatic cancer arises from a mix of genetics, lifestyle, and inflammation, review finds.
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
High prevalence of microvascular and macrovascular complications among adult Ugandans with diabetes
High rates of diabetes complications found in adult Ugandans
This meta-analysis examined the prevalence of various diabetic complications, including neuropathy and retinopathy, in a large cohort of adu…
More than half of Ugandan adults with diabetes suffer from nerve damage, highlighting a critical need for earlier screening and better care.
SGLT2 inhibitors associated with lower all-cause mortality in heart transplant recipients with type 2 diabetes
SGLT2 inhibitors associated with lower mortality in heart transplant patients
This meta-analysis examined the impact of SGLT2 inhibitor use on outcomes for heart transplant recipients with type 2 diabetes. The authors …
New analysis suggests SGLT2 inhibitors may lower death rates for heart transplant recipients with type 2 diabetes without increasing UTI ris…
Immunometabolic dysregulation drives hyperalgesia and hypoesthesia in diabetic peripheral neuropathy
New research explores how inflammation drives nerve damage in diabetes
This narrative review explores the pathophysiology of diabetic peripheral neuropathy, focusing on how hyperglycemia, lipotoxicity, and intes…
Chronic high blood sugar causes more than just high glucose; it triggers a cycle of inflammation and immune stress that damages nerves.
Single-incision sleeve plus bypass shows short-term safety and metabolic improvement in 3 patients with obesity and T2DM
SILSG-JJB Procedure Shows Promise for Weight Loss and Diabetes
This case report and review describes 3 female patients with severe obesity and type 2 diabetes who underwent single-incision laparoscopic s…
A new surgical approach may help people with severe obesity and Type 2 Diabetes achieve weight loss and better blood sugar levels.
Transcriptomic analysis identifies 337 high-confidence genes associated with Type 2 Diabetes in human pancreatic islets
Meta-analysis reveals 337 genes linked to type 2 diabetes in islets
This meta-analysis of transcriptomic data from human pancreatic islets identified 337 high-confidence T2D-associated genes. The study also d…
A meta-analysis of human pancreatic islets identified 337 high-confidence genes tied to type 2 diabetes, and a 10-gene panel perfectly disti…
Questions about Type 1 Diabetes
Does the FDA approved drug Tzield delay the onset of Stage 3 Type 1 diabetes?
Yes, the FDA-approved drug Tzield (teplizumab) delays the onset of Stage 3 type 1 diabetes in people with Stage 2 disease.
Full answer →Can semaglutide help reduce the total daily insulin dose for adults with Type 1 diabetes?
Yes, semaglutide can reduce total daily insulin dose in adults with type 1 diabetes and overweight or obesity, based on clinical trial and real-world data.
Full answer →