How many clinical trials are tracked for Cirrhosis?

82 trials are tracked, 2 with published results.

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Cirrhosis

Subtypes of Cirrhosis

Primary biliary cholangitis 8 Liver Fibrosis 7 Decompensated liver cirrhosis 6 Fibrosis 4 Compensated cirrhosis 3 Keloid 2 Acute decompensation of cirrhosis 1 Compensated MASH cirrhosis 1 Decompensated liver failure 1 End-stage liver disease 1

47 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Cirrhosis

82 trials tracked for Cirrhosis: 27 in phase 3 or 4 and 2 with published results. The most-cited published study has 45 citations.

82Trials tracked

27Phase 3 & 4

0Recruiting

2With published results

Phase distribution

Phase 4 12 Phase 3 15 Phase 2 22 Phase 1 3 Other / NA 30

Phase 4 The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy Completed · 45 cited
Phase 3 Implications of Fecal Microbiota Transplantation in Modulating the Effects of Liver Cirrhosis Completed · 15 cited
Phase 4 Study of Long-term Peg Intron vs. Colchicine in Non-responders. Completed
Phase 4 Study to Evaluate the Safety and Efficacy of Daclatasvir/Sofosbuvir/Ribavirin for 16 Versus 24 Weeks for HCV Genotype 3 Cirrhotics Completed
Phase 4 Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant Completed
Phase 4 Efficacy and Safety of Anticoagulant Therapy in Portal Vein Thrombosis Completed

Show 44 more trials

Phase 4 Ramelteon for Treatment of Insomnia in Cirrhosis Completed
Phase 4 PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors) Completed
Phase 4 Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis Completed
Phase 4 Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis Completed
Phase 4 Tolvaptan for Ascites in Cirrhotic Patients Completed
Phase 4 Steroid Free Immunosuppression in Liver Transplantation Completed
Phase 4 Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis Completed
Phase 3 A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus Infection Completed
Phase 3 Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study Completed
Phase 3 Is Adrenal Insufficiency Under-diagnosed in Hospitalized Cirrhosis Patients? Completed
Phase 3 A Trial to Improve Quality of Life in People With Cirrhosis Completed
Phase 3 Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment Completed
Phase 3 Effects of Pegylated Interferon Alfa-2b and Ribavirin After Orthotopic Liver Transplantation in Subjects With Chronic Hepatitis C Recurrence (P04590AM3)(COMPLETED) Completed
Phase 3 Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis Completed
Phase 3 Efficacy and Safety of Peginterferon Alfa-2b and Ribavirin Therapy in Subjects With Type C Compensated Liver Cirrhosis (Study P05116) Completed
Phase 3 A Trial to Investigate the Efficacy of OPC-41061 Administered at a Dose of 7.5 mg in Patients With Hepatic Edema Completed
Phase 3 PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus Ribavirin (Study P02370) Completed
Phase 3 A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema Completed
Phase 3 A Trial of OPC-41061 in Patients With Hepatic Edema - Investigation of the Safety of Treatment at 7.5 mg Beyond 7 Days and of the Effect of Dose Escalation to 15 mg Completed
Phase 3 Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis Completed
Phase 3 Peg-Intron for Prevention of Disease Progress in Chronic Hepatitis C Patients With Cirrhosis (Study P02569) Completed
Phase 2 A Study of Experimental Medication BMS-986263 in Adults With Advanced Hepatic Fibrosis After Cure of Hepatitis C Completed
Phase 2 Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients Completed
Phase 2 FMT in Cirrhosis and Hepatic Encephalopathy Completed
Phase 2 Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation Completed
Phase 2 A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy Completed
Phase 2 A Study of IDN-6556 in Subjects With Liver Cirrhosis Completed
Phase 2 A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV Completed
Phase 2 VE303 for Treatment of Hepatic Encephalopathy (HE) Completed
Phase 2 A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV Completed
Phase 2 A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK Completed
Phase 2 A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension Completed
Phase 2 A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients Completed
Phase 2 A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver Cirrhosis Completed
Phase 2 New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C Completed
Phase 2 Human Fetal Liver Cell Transplantation in Chronic Liver Failure Completed
Phase 2 Safety and Efficacy of Baclofen for Treatment of Muscle Spasms in Patients With Cirrhosis: A Pilot Study Completed
Phase 2 Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory Ascites Completed
Phase 2 A Dose-defining Study of OPC-41061 in Treatment of Hepatic Edema Completed
Phase 2 Erlotinib Hydrochloride in Preventing Liver Cancer in Patients With Cirrhosis of the Liver Completed
Phase 2 Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension Completed
Phase 2 MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy) Completed
Phase 2 [18F]FMISO PET/CT After Transcatheter Arterial Embolization in Imaging Tumors in Patients With Liver Cancer Completed
Phase 1 Open Label Single Dose Phase I Trial of BI 201335 to Study Pharmacokinetics and Safety in Patients With Compensated Liver Cirrhosis Completed

Showing the 50 most-cited and recently-updated of 82 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

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Questions about Cirrhosis

How common is depression among patients with liver cirrhosis?

Depression is very common in liver cirrhosis, affecting about 37% of patients globally, yet it often goes undiagnosed.

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Can the Patient Buddy App help reduce hospital readmissions for my cirrhosis?

Yes, the Patient Buddy App reduced avoidable hospital readmissions in cirrhosis patients by about half in a clinical trial, but discuss with your doctor if it's right for you.

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