Repetitive transcranial magnetic stimulation shows promise for improving cognition and executive function in patients with mild cognitive impairment
Magnetic stimulation may boost thinking skills in mild cognitive impairment
A systematic review and meta-analysis of 532 patients with mild cognitive impairment found that repetitive transcranial magnetic stimulation…
A review of five studies found that repetitive magnetic stimulation improved thinking and memory in people with mild cognitive impairment, t…
AI-assisted PET radiomics improves Alzheimer's diagnosis over conventional methods in meta-analysis
AI helps PET scans spot early Alzheimer’s with new precision
A systematic review of 5,765 patients shows AI radiomics significantly boosts diagnostic accuracy for Alzheimer's versus mild cognitive impa…
AI-powered PET scans may better distinguish early Alzheimer’s from mild memory loss, but results for healthy people are less clear.
Systematic review and meta-analysis shows computerized cognitive training improves mild cognitive impairment
Daily Computer Brain Exercises Sharpen Thinking During Early Memory Loss
This systematic review and meta-analysis evaluated computerized cognitive training (CCT) in patients with mild cognitive impairment. The ana…
• Computer training noticeably boosts memory and focus for mild cognitive decline • Helps adults noticing early memory slips like forgetting…
Systematic review of 88 observational studies on missing data reporting in T2DM-MCI research
Missing Data in Diabetes Studies Could Skew Brain Health Results
This systematic review analyzed 88 observational studies related to Type 2 Diabetes Mellitus with Mild Cognitive Impairment. Only 22.7% of s…
A review of 88 studies on diabetes and mild cognitive impairment found that only 1 in 5 properly reported missing data, which could lead to …
Systematic review and meta-analysis of Zingiberaceae-derived interventions for memory-related outcomes in adults
Turmeric and Ginger May Boost Memory, New Research Shows
This systematic review and meta-analysis evaluated Zingiberaceae-derived interventions, including curcumin, turmeric, ginger, and related pr…
Forget the spice rack debate: turmeric and ginger may actually sharpen your memory, but only for certain types of thinking, according to a n…
Ashwagandha supplementation shows cognitive and physical benefits in adults
Your Brain and Muscles Could Get Stronger with This Common Herb
A meta-analysis of 20 studies found ashwagandha significantly improved memory, attention, and muscle strength in adults, with no effect on b…
• Ashwagandha significantly boosts memory and muscle strength in adults • Helps adults seeking natural cognitive and physical support daily …
Meta-analysis finds combined exercise and tDCS improves cognition in older adults
Combined exercise and brain stimulation may help older adults with memory
This meta-analysis of randomized controlled trials synthesized evidence on combined exercise and transcranial direct current stimulation for…
A review of trials suggests pairing exercise with brain stimulation can boost memory and thinking in older adults with cognitive issues.
Narrative review links soil contaminants and micronutrient depletion to hypertension, atherosclerosis, and neurodegenerative processes
The Hidden Link Between Dirty Soil and Your Heart and Brain
This narrative review synthesizes a plausible pathophysiologic framework linking soil contaminants and depleted essential micronutrients to …
The soil your food grows in may be quietly damaging your heart and brain, and experts say we have been overlooking this danger for too long.
Systematic review and meta-analysis reports 36.6% cognitive impairment prevalence in coronary heart disease patients
Older patients with heart disease and stroke history face higher risk of thinking problems
This systematic review and meta-analysis evaluates risk factors for cognitive impairment in patients with coronary heart disease. The pooled…
A large study found that nearly 37% of patients with heart disease have cognitive issues. Age, past strokes, and smoking all increase this r…
ICU CogHab cognitive rehabilitation feasibility study in ICU survivors with cognitive impairment
Feasibility study tests cognitive rehab for ICU survivors with cognitive impairment
This randomised controlled feasibility study evaluated a cognitive rehabilitation intervention in 83 ICU survivors with cognitive impairment…
A feasibility study found that cognitive rehabilitation can be introduced to ICU survivors, though recruitment and retention remain challeng…
Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults
Digital tools may boost brain health in older adults
This systematic review and meta-analysis evaluated digital technology interventions in older adults with cognitive impairment, depression, a…
Using digital technology like apps or online programs may improve thinking skills and mood in older adults, a new analysis suggests.
Narrative review discusses pharmacological and lifestyle interventions for type 2 diabetes and psychological health
New hope for diabetes patients struggling with anxiety and depression
This narrative review examines the relationship between type 2 diabetes and conditions such as anxiety, depression, and cognitive impairment…
Diabetes drugs that control blood sugar might also help improve mood and reduce anxiety for patients living with the condition.
Research across Cognitive Dysfunction
Related studies from across the Cognitive Dysfunction family.
Food insecurity linked to poorer diet and higher obesity risk in older adults
Food Insecurity Linked to Poorer Diet and Obesity in Older Adults
This narrative review synthesizes evidence linking food insecurity and financial hardship to poorer diet quality and higher odds of overweig…
Older adults facing food insecurity eat worse and are more likely to be obese, a review finds.
Younger US men show sharp loneliness increase, older men stable, systematic review finds
Loneliness Linked To Health Risks In Men Across The United States
This systematic review of 30 core studies on US men found no widespread epidemic of loneliness, but younger men (ages 18–29) show a sharp in…
A review of 30 studies finds loneliness in men is linked to depression, heart disease, and higher mortality, with younger men facing a sharp…
Review of ferroptosis role in postoperative cognitive dysfunction in older surgical patients
Aging and surgery may trigger brain cell death in older patients
This narrative review examines the potential role of ferroptosis in postoperative cognitive dysfunction among older surgical patients. The a…
A review suggests aging and surgery might trigger brain cell death in older patients, but scientists are not sure if this process causes the…
Preoperative psychological factors are associated with postoperative cognitive outcomes in older adults
Psychological factors linked to cognitive issues after surgery in older adults
This systematic review and meta-analysis examined preoperative psychological factors in older adults aged 60 years or older.
A large review links preoperative anxiety and stress to worse cognitive outcomes after surgery for older patients.
Meta-analysis finds 24% incidence of cognitive dysfunction after pediatric liver transplant
Nearly 1 in 4 kids face thinking problems after liver transplant
This meta-analysis of 7494 children after liver transplantation reports a pooled incidence of cognitive dysfunction of 24% (95% CI: 19.0%-30…
One in four children develops thinking problems after a liver transplant, with infants facing the highest risk.
Framingham cohort links longitudinal brain atrophy patterns to cognitive decline and AD biomarkers in community-based participants
Brain shrinkage patterns predict Alzheimer's risk in older adults
This community-based cohort study of 300 participants from the Framingham Heart Study analyzed longitudinal brain atrophy patterns using MRI…
A study of 300 older adults found specific brain shrinkage patterns that strongly predict Alzheimer's disease and worse thinking skills.
Living alone not linked to incident dementia but associated with higher institutionalization risk in a cohort of 2,269 individuals
Living Alone Does Not Raise Dementia Risk But Increases Care Needs
This French clinic-based cohort study followed 2,269 individuals with cognitive complaints or mild cognitive impairment for a median of 5 ye…
Living alone does not increase dementia risk, but it does raise the chance of needing nursing home care later.
Bibliometric review of anesthesia-associated postoperative cognitive dysfunction in elderly patients from 2000 to 2024
Why Your Brain Fog After Surgery Might Start in Your Gut
This bibliometric review analyzed 923 publications indexed in the Web of Science Core Collection and PubMed database regarding anesthesia-as…
Understanding how surgery and anesthesia trigger brain inflammation could lead to new ways to prevent memory loss after operations.
Phase 2 RCT of exercise plus ibuprofen for cancer-related cognitive impairment shows mixed cognitive outcomes
Exercise and Common Pain Reliever May Sharpen Thinking During Chemo
This phase 2 randomized controlled trial enrolled 86 patients with cancer receiving chemotherapy reporting cognitive problems.
You’re in the middle of chemotherapy. You love your family, your work, your life.
Menopausal hormone therapy initiation around menopause linked to increased Alzheimer's risk
Hormone Therapy and Dementia: The Truth About Timing
This systematic review and meta-analysis of 213,678 menopausal women found that initiating systemic menopausal hormone therapy (MHT) around …
Many women look to hormone therapy to ease the hot flashes and mood swings of menopause.
Narrative review covers cardiovascular conditions and cognitive decline without reported trial data
Your Heart and Brain Are Talking to Each Other
This narrative review addresses a broad scope of cardiovascular conditions, including stroke, heart failure, atrial fibrillation, and ischem…
Imagine your heart and brain as two best friends who never stop texting each other.
PDE5 inhibitors increased cerebral blood flow in white matter hyperintensity regions in adults with cerebral small vessel disease
An Old Drug Class May Protect the Brain From Silent Damage
This systematic review and meta-analysis evaluated phosphodiesterase-5 inhibitors (sildenafil or tadalafil) versus placebo in 236 adults wit…
Drugs already approved for other conditions may help restore blood flow in a part of the brain that quietly fuels strokes and dementia.
Questions about Mild Cognitive Impairment
Does losing the sense of smell mean mild cognitive impairment will become dementia?
Losing your sense of smell is a warning sign that mild cognitive impairment may progress to dementia, but it does not guarantee it will happen.
Full answer →Can brain shrinkage patterns predict when mild cognitive impairment turns into Alzheimer's disease?
Yes, specific brain shrinkage patterns, especially in the precuneus and fusiform gyrus, can help predict progression from mild cognitive impairment to Alzheimer's disease, but more research is needed.
Full answer →Is replacing plasma with young donor blood safe for people with mild cognitive impairment?
A small pilot study found that replacing plasma with young donor blood is feasible and appears safe in the short term for people with mild cognitive impairment, but larger, longer-term studies are needed.
Full answer →Does type 2 diabetes affect psychological health and cognitive impairment?
Yes, type 2 diabetes is linked to higher risks of depression, anxiety, and cognitive impairment, partly through the gut-brain axis and metabolic effects.
Full answer →