REDDI pipeline improves balanced accuracy for classifying MCI, MS, Parkinson's, and ALS using MEG data.
Can a new computer tool help doctors spot brain diseases faster and more accurately?
This study developed a machine learning framework called REDDI that utilizes MEG resting-state data and Riemannian geometry for classifying …
A new computer tool helps doctors distinguish between hard-to-tell-apart brain diseases like Parkinson's and ALS with 13% better accuracy.
Home-based e-based exercise protocol feasibility study for patients with multiple sclerosis and comorbidities
Working Out From Home Could Slow Multiple Sclerosis Progression
This protocol describes a home-based e-based physical exercise program for patients with multiple sclerosis (pwMS) with and without comorbid…
A new trial tests if twice-weekly online resistance exercise from home can improve walking ability and reduce disease activity in people wit…
Rituximab exposure is associated with serum sickness in patients with multiple sclerosis, nephrotic syndrome, or immune thrombocytopenia.
Can taking Rituximab cause a severe allergic reaction that returns if you take it again?
This retrospective review analyzed 39 published case reports of patients with rituximab-induced serum sickness (RISS). The study describes c…
Taking Rituximab can trigger a delayed allergic reaction that returns in most patients if the drug is given again, so doctors must use extre…
Network meta-analysis of six exercise modalities in females with multiple sclerosis shows improvements in fatigue, quality of life, balance, depression, and mental health.
Which Workout Helps MS Most? The Winner Surprised Researchers
This network meta-analysis evaluated six distinct training programs or exercise modalities in females with multiple sclerosis compared to co…
Almost any regular movement helps women with MS, but yoga pulled ahead for fatigue and emotional well-being while classic aerobics won on ba…
Chiropractic thoracic spinal manipulation showed moderate effects on cytokines in a pilot RRMS trial.
Spinal tweak lowers inflammation in MS patients
This randomized, sham-controlled pilot study enrolled 21 participants with relapsing-remitting multiple sclerosis. Chiropractic thoracic spi…
A spinal tweak combined with muscle therapy lowered inflammation markers in people with multiple sclerosis, offering a new way to calm the i…
Respiratory muscle training improves respiratory muscle strength and pulmonary function in multiple sclerosis patients.
A Simple Breathing Exercise May Strengthen a Core MS Symptom
This systematic review and meta-analysis evaluated respiratory muscle training (RMT) in 542 individuals with multiple sclerosis compared to …
Strengthening the muscles used to breathe can directly improve respiratory function for people with multiple sclerosis, offering a new layer…
Cladribine tablets maintain stable patient-reported outcomes in highly active MS over 52 weeks
Your Fitness Tracker Could Now Help Manage Your Multiple Sclerosis
An interim analysis of a prospective observational study in 190 Italian patients with highly active MS found that cladribine tablets maintai…
Multiple sclerosis patients using cladribine tablets maintain physical function while wearables track symptoms continuously between doctor v…
Sex differences in disability and demographics observed in a Swiss Multiple Sclerosis Cohort
MS Hits Men and Women Differently. Here’s What That Means for You.
This cross-sectional analysis of 1,541 patients with relapsing-remitting or progressive multiple sclerosis examined sex differences in disab…
Multiple sclerosis starts earlier in women and disability builds differently in men, meaning treatment plans must account for these sex diff…
China's rehabilitation needs for neurological disorders increased significantly from 1990 to 2021.
A Silent Wave of Disability is Rising. Here’s Who’s Most at Risk.
This cross-sectional analysis of data from China between 1990 and 2021 examined rehabilitation needs for ten neurological conditions, includ…
China faces a rising wave of neurological disability driven by aging, with stroke, Alzheimer's, and Parkinson's creating urgent long-term ca…
FDG-PET reveals dysregulated glucose metabolism as a common feature across late-onset neurodegenerative diseases with unique patterns.
FDG-PET scans show common brain glucose changes across several late-onset neurodegenerative diseases
This meta-analysis of 5,412 individuals with age-associated neurodegenerative diseases (A2ND) and 3,549 controls utilized FDG-PET to quantif…
FDG-PET scans reveal that dysregulated brain glucose metabolism is a shared feature across late-onset neurodegenerative diseases like Alzhei…
Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury.
Could brainstem plastic changes trigger spasticity in stroke and spinal cord injury patients?
This systematic review examined pathophysiological similarities in spasticity among humans, primates, and rodents. Evidence remains limited …
Spasticity after stroke or spinal cord injury may stem from plastic changes in the brainstem, though evidence remains limited and controvers…
Luteolin shows neuroprotective potential in preclinical models for Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis.
Luteolin shows potential benefits in early studies for neurodegenerative diseases
This review of preclinical studies and preliminary clinical observations suggests luteolin may reduce neuroinflammation and improve function…
Luteolin may help slow brain decline in Alzheimer's and Parkinson's by calming inflammation and boosting antioxidant defenses in early studi…