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Neurology
Cohort
Normative MRI modelling identifies critical brain volume deviations associated with disability in multiple sclerosis.
Do brain scans show more warning signs of disability in multiple sclerosis than in healthy people?
This observational cohort study applied a normative model trained on 62,444 healthy MRI datasets to scans from 362 people with multiple scle…
Brain scans reveal that people with multiple sclerosis have more critical volume deviations than healthy individuals, directly linked to hig…
medRxiv
Apr 9, 2026
Neurology
Cohort
CSF proteomic signatures show potential for MS diagnosis and prognosis in cohort study
Could a spinal fluid test predict how multiple sclerosis will progress?
A multicentric cohort study of 120 patients with multiple sclerosis, clinically isolated syndrome, and healthy controls analyzed cerebrospin…
A spinal fluid test with ten proteins could predict multiple sclerosis progression, showing promise for forecasting disease activity up to f…
medRxiv
Apr 4, 2026
Neurology
RCT
Online behavioral intervention increases physical activity and improves depression in newly diagnosed multiple sclerosis
Can online coaching help people newly diagnosed with MS get moving and feel better?
A pilot randomized controlled trial in 50 people newly diagnosed with MS found that a 16-week COM-B-based online behavioral intervention sig…
Online coaching helped newly diagnosed MS patients add 11 minutes of daily activity, feel less depressed, and improve mental health quality …
Apr 3, 2026
Neurology
FDA Approval
FDA Approves Kesimpta (ofatumumab) for Relapsing Forms of Multiple Sclerosis in Adults
The FDA approved a new monthly self-injection drug for multiple sclerosis.
The FDA has approved Kesimpta, a CD20-directed cytolytic antibody, for the treatment of relapsing forms of multiple sclerosis in adults. The…
The FDA approved Kesimpta, a new monthly self-injection for adults with relapsing forms of multiple sclerosis.
FDA
Apr 3, 2026
Neurology
RCT
Neuromuscular electrostimulation plus swallowing therapy may benefit dysphagia in severely disabled MS patients
Can electrical stimulation help people with MS swallow more easily?
A randomized controlled trial in 101 people with MS and dysphagia found both traditional swallowing therapy plus neuromuscular electrostimul…
For people with advanced multiple sclerosis, adding gentle electrical stimulation to standard swallowing therapy led to significantly greate…
Apr 3, 2026
Neurology
Meta-analysis
Percutaneous balloon compression shows initial pain relief in multiple sclerosis-related trigeminal neuralgia
Balloon compression procedure shows initial pain relief for MS-related facial pain
A systematic review and meta-analysis of 12 studies involving 386 patients with MS-related trigeminal neuralgia found percutaneous balloon c…
A balloon compression procedure offers immediate pain relief for most people with severe facial pain caused by multiple sclerosis, though lo…
Apr 2, 2026