GLP-1RAs reduce MACE risk in Asian and White adults with diabetes or overweight
Do heart benefits from diabetes drugs work equally well across different races?
A meta-analysis of 74,703 adults with type 2 diabetes or overweight/obesity found GLP-1RAs reduced MACE risk versus placebo. The reduction w…
Diabetes drugs protect hearts in Asian and White adults, but the benefit for Black adults remains unclear due to small study numbers.
Phase 1b trial of oral GLP-1 agonist HDM1002 shows weight reduction in Chinese adults with overweight/obesity
Can a new pill help with weight loss? Early trial shows promise.
A phase 1b randomized controlled trial in Chinese adults with overweight/obesity without diabetes found greater weight reductions with oral …
A new oral weight-loss pill helped adults lose about 6 kilograms in just 28 days, showing early promise compared to a placebo.
Prediabetes in youth with overweight/obesity associated with lower baseline cognition, stable over 2 years
Could prediabetes affect how young people with obesity think and learn?
A 2-year longitudinal observational study of 67 youth with overweight/obesity found those with prediabetes had lower IQ and poorer executive…
Youth with prediabetes show lower IQ and slower thinking skills compared to peers with normal blood sugar, and these cognitive differences s…
Horseshoe-like plantar hyperkeratosis associated with prediabetes in overweight adults
Could a specific foot skin change be a visible clue for prediabetes?
A cross-sectional cohort study of 191 adults with overweight or obesity found horseshoe-like plantar hyperkeratosis (HSLPH) was more frequen…
A horseshoe-shaped patch of thickened skin on the foot is a strong visual clue for prediabetes in adults with overweight or obesity.
FDA Approves FOUNDAYO (orforglipron) for chronic weight management in adults with obesity or overweight with comorbidities.
The FDA has approved a new daily pill called FOUNDAYO to help adults manage their weight.
The FDA has approved FOUNDAYO (orforglipron), an oral GLP-1 receptor agonist, for chronic weight management in adults with obesity or overwe…
FDA approves new daily pill FOUNDAYO for adults to manage weight alongside diet and exercise.
Tirzepatide improves patient-reported physical function in adults with overweight or obesity
Tirzepatide may improve physical function for adults with overweight or obesity
A meta-analysis of 4,531 participants found that once-weekly tirzepatide 10 or 15 mg significantly improved physical function scores compare…
Adults with overweight or obesity taking tirzepatide reported better physical function scores on two questionnaires compared to those taking…
Network meta-analysis compares exercise types for insulin resistance in youth with overweight or obesity
Which exercise works best for insulin resistance in kids with extra weight?
A network meta-analysis of 63 RCTs involving 3,286 children and adolescents with overweight or obesity compared exercise modalities. HIIT wa…
For kids with extra weight, short bursts of intense exercise best lower insulin levels, while mixing cardio and weights works best for dropp…
Phase 1 trial of once-weekly eloralintide shows weight reduction in obesity over 12 weeks
Can a new weekly injection help people lose weight? Early results show promise.
A Phase 1 randomised controlled trial in 100 participants with obesity or overweight found that once-weekly subcutaneous eloralintide result…
A new weekly shot helped people with obesity lose between 2.6% and 11.3% of their body weight in early safety testing, though larger studies…
Mediterranean lifestyle intervention reduces BMI, fat mass in preschool girls at risk of obesity
Could a Mediterranean lifestyle help preschool girls at risk of obesity? A new study suggests it might.
In a 12-month RCT of 206 preschoolers at risk of obesity, a Mediterranean lifestyle intervention (diet, physical activity) significantly red…
A Mediterranean lifestyle improved body fat and BMI for preschool girls at risk of obesity, but the same healthy habits did not help boys in…